Medical Premises

Rancho Santa Margarita, CA Medical Office Space for Sale

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Mission Viejo, CA Trabuco Canyon, CA Lake Forest, CA Silverado, CA Ladera Ranch, CA Irvine, CA Laguna Woods, CA Laguna Hills, CA
Upgraded Office Condo For Sale
Updated: Nov 26, 2025
Upgraded Office Condo For Sale

30372 Esperanza, Rancho Santa Margarita, CA 92688

$1,585,500
3,020 sqft
Approved for medical use
Features 7 private offices
Conference room available
Easy access to the 241 Foothill Transportation Corridor
Includes a reception area
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This listing looks promising.

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30372 Esperanza, Rancho Santa Margarita, CA 92688

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Medical Office Condo Suite
Updated: Jun 10
Medical Office Condo Suite

30212 Tomas, Rancho Santa Margarita, CA 92688

Contact for pricing
2,360 sqft
Office condo with 6 private offices
Includes a conference room
Features a private balcony
Medical use possible
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Freestanding Office Building with Patio
Freestanding Office Building with Patio

29883 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

$8,279,700

Freestanding office/medical building featuring a private patio and extensive glass with polished concrete interiors.

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Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 3 Active listings in Rancho Santa Margarita, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Freestanding Medical Building For Sale
Freestanding Medical Building For Sale

11 Mareblu, Aliso Viejo, CA 92656

$13,850,000
11,524 sqft

Freestanding medical building remodeled in 2020 and 2024.

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Furnished Second-Floor Office Condo
Furnished Second-Floor Office Condo

23232 PERALTA DR, Laguna Hills, CA 92653

Contact for pricing
1,234 sqft

Turnkey second-floor office condo includes three private offices and a reception/work area with furnishings included.

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Multi-Tenant Office Building
Multi-Tenant Office Building

135 Columbia, Aliso Viejo, CA 92656

$9,800,000
24,552 sqft

Elevator-served office building with a modern, high-finish lobby and natural light throughout common areas.

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Laguna Hills Office Condo
Laguna Hills Office Condo

23232 Peralta Drive 117, Laguna Hills, CA 92653

$49,900
574 sqft 0.01 AC lot

Office condo for sale or lease in Laguna Hills.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Murrieta Land Near Medical Center
Murrieta Land Near Medical Center

28330 Joan Dunn Lane, Murrieta, CA 92563

Contact for pricing
1,952 sqft 2.65 AC lot

2.65-acre vacant land parcel near Loma Linda University Medical Center.

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Commercial Development Land Parcel
Commercial Development Land Parcel

42079 Roick, Temecula, CA 92590

$1,249,000
1.23 AC lot

1.23-acre commercial-zoned land with plans for significant development in Temecula.

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Service Commercial Development Land
Service Commercial Development Land

31528 Yucaipa Boulevard, Yucaipa, CA 92399

$550,000

Zoned Service Commercial and positioned for convenient I-10 East access in Yucaipa for multiple retail or office concepts.

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Commercial Land Parcel with Road Frontage
Commercial Land Parcel with Road Frontage

Bear Valley Road, Victorville, CA 92392

$595,000
9.77 AC lot

9.77-acre commercial parcel with long Bear Valley Road frontage for commercial development under zoning C.

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Off-Market Properties in Rancho Santa Margarita, CA

Consider similar Off-Market properties in Rancho Santa Margarita, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

29821-29941 Aventura
Neighborhood centers

29821-29941 Aventura, Rancho Santa Margarita, CA 92688

Value Estimation by Request
87,331 sqft
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30212 Tomas
Medical Office Space

30212 Tomas, Rancho Santa Margarita, CA 92688

Value Estimation by Request
1,365 sqft
View details

Rancho Santa Margarita, CA Medical Office Space Market Trends and Statistics

Explore 5 medical office space for sale in Rancho Santa Margarita, CA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 5,380 square feet of properties for sale, with an estimated market value of $9,865,200.

Sale prices for medical spaces in Rancho Santa Margarita, CA start at $1,585,500, averaging $4,932,600, and reaching up to $8,279,700 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 8
Office buildings 6
Medical Office Space 5
Coworking space 1

Demographics Overview

Population 44K
Population Growth (5Y) -2.8%
Median Household Income $142,015
College Educated 64.8%

High-Yield Neighborhoods for Investment

Identify Rancho Santa Margarita submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
92688 $4.9M

Taxes & Financing

Tax Rate (average for all types) 0.92%
Property Tax per SF $8.34 per SF
Tax Rate vs County Average 0.17 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Orange County

New Delisted

Total CRE Inventory on Market (SF)

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