Medical Premises

Rancho Santa Margarita, CA Medical Office Space for Sale

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Mission Viejo, CA Coto De Caza, CA Trabuco Canyon, CA Lake Forest, CA Silverado, CA Ladera Ranch, CA Irvine, CA Laguna Woods, CA
Freestanding Medical Office Building For Sale
Updated: Nov 26, 2025
Freestanding Medical Office Building For Sale

29803 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

$3,645,600
6,076 sqft
Freestanding, single‑story medical office building.
Divisible to 4,777 & 1,299 SF.
Ample parking with a 4:1000 parking ratio.
Enjoy a campus setting with Santa Barbara style architecture.
Walking distance to numerous retail amenities.
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Freestanding Office Building with Patio
Updated: Jul 29
Freestanding Office Building with Patio

29883 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

$8,279,700
Freestanding office/medical building with private patio
Extensive glass storefront and interior glazing
Polished concrete flooring with exposed ceilings
Upgraded finishes throughout
EV car chargers on site
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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 2 Active listings in Rancho Santa Margarita, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Freestanding Medical Building For Sale
Freestanding Medical Building For Sale

11 Mareblu, Aliso Viejo, CA 92656

$13,850,000
11,524 sqft

Freestanding medical building remodeled in 2020 and 2024.

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Second-Floor Medical Office Condo
Second-Floor Medical Office Condo

21068 Bake Pkwy, Lake Forest, CA 92630

Contact for pricing
6,392 sqft

Condominium office space supports medical and professional office use in a second-floor setting.

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Medical Office Condo with Loading Door
Medical Office Condo with Loading Door

20902 Bake Pkwy, Lake Forest, CA 92630

Contact for pricing
2,564 sqft

Medical office condominium with flex-oriented physical features and dedicated loading access.

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Multi-Tenant Office Building
Multi-Tenant Office Building

135 Columbia, Aliso Viejo, CA 92656

$9,800,000
24,552 sqft

Elevator-served office building with a modern, high-finish lobby and natural light throughout common areas.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Murrieta Land Near Medical Center
Murrieta Land Near Medical Center

28330 Joan Dunn, Murrieta, CA 92563

$1,400,000
1,952 sqft 2.65 AC lot

2.65-acre vacant land parcel near Loma Linda University Medical Center.

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Commercial Land Development Site
Commercial Land Development Site

42079 Roick, Temecula, CA 92590

$1,199,000
1.23 AC lot

Commercial-zoned parcel in Temecula with plans associated with future commercial development.

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Off-Market Properties in Rancho Santa Margarita, CA

Consider similar Off-Market properties in Rancho Santa Margarita, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

29821-29941 Aventura
Neighborhood centers

29821-29941 Aventura, Rancho Santa Margarita, CA 92688

Estimated value:
No data
87,331 sqft
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30212 Tomas
Medical Office Space

30212 Tomas, Rancho Santa Margarita, CA 92688

Estimated value:
No data
1,365 sqft
View details

Rancho Santa Margarita, CA Medical Office Space Market Trends and Statistics

Explore 4 medical office space for sale in Rancho Santa Margarita, CA on our real estate platform. These investment opportunities span a total of 6,076 square feet of properties for sale, with an estimated market value of $11,925,300.

Sale prices for medical spaces in Rancho Santa Margarita, CA start at $3,645,600, averaging $5,962,650, and reaching up to $8,279,700 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office Units 8
Medical Office Space 3
Office buildings 3
Coworking space 1

Demographics Overview

Population 44K
Population Growth (5Y) -2.8%
Median Household Income $142,015
College Educated 64.8%

High-Yield Neighborhoods for Investment

Identify Rancho Santa Margarita submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
92688 $6M

Taxes & Financing

Tax Rate (average for all types) 0.92%
Property Tax per SF $8.34 per SF
Tax Rate vs County Average 0.17 pp below county avg
Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in Orange County

New Delisted

Total CRE Inventory on Market (SF)

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