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    Rancho Santa Margarita, CA

    Rancho Santa Margarita, CA Commercial Real Estate for Lease

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    19 properties
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    Flexible Workspace Solutions at Koll Center. Contact us today to book a tour!
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    Freestanding Building with Extensive Glass
    Updated: Nov 26, 2025
    Freestanding Building with Extensive Glass

    23142 Arroyo Vista, Rancho Santa Margarita, CA 92688

    $500/Mo
    5,810 sqft
    Prime South Orange County location
    Excellent access to the 241 FTC
    Freestanding single‑story building with an extensive glass line
    Close proximity to numerous retail amenities
    Year Built: 2002
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    Corner Flex Space with Street Frontage
    Updated: Aug 19
    Corner Flex Space with Street Frontage

    30012 Aventura, Rancho Santa Margarita, CA 92688

    Contact for pricing
    7,420 sqft
    7,420‑square‑foot flex space available for lease
    Corner location with major street frontage
    Business park setting
    Office area can be reduced
    Potential fenced yard area
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    Rancho Santa Margarita Retail Center
    Rancho Santa Margarita Retail Center

    29821-29941 Aventura, Rancho Santa Margarita, CA 92688

    Contact for pricing
    8,500 sqft

    Multi-tenant center near 241 Toll Road in Rancho Santa Margarita.

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    Office Unit for Sublease
    Office Unit for Sublease

    30052 Aventura, Rancho Santa Margarita, CA 92688

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    577 sqft

    Professional office accommodation offered within a building completed in 1998.

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    Retail Space
    Retail Space

    30465 Avenida De Las Flores, Rancho Santa Margarita, CA 92688

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    1,345 sqft

    Retail premises available for lease in Rancho Santa Margarita.

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    Rancho Santa Margarita Retail Space
    Rancho Santa Margarita Retail Space

    30602-30616 Santa Margarita Pky, Rancho Santa Margarita, CA 92688

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    1,104 sqft

    Retail space in shopping center with strong anchor tenants.

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    Rancho Santa Margarita Retail Center
    Rancho Santa Margarita Retail Center

    30451-30465 Avenida de las Flores, Rancho Santa Margarita, CA 92688

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    275,000 sqft

    275,000 SF power center with excellent visibility and access.

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    Fire-Sprinklered Warehouse with Air Conditioning
    Fire-Sprinklered Warehouse with Air Conditioning

    22412 Gilberto, Rancho Santa Margarita, CA 92688

    Contact for pricing
    5,758 sqft

    Fire-sprinklered warehouse space with 100% air conditioning, a single grade-level door, and high clear height.

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    Office Building with Mountain Views
    Office Building with Mountain Views

    22362 Gilberto, Rancho Santa Margarita, CA 92688

    Contact for pricing
    18,538 sqft

    Two-story office building in South Orange County available for rent.

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    Industrial Warehouse with Fenced Yard
    Industrial Warehouse with Fenced Yard

    29720 Avenida de las Banderas, Rancho Santa Margarita, CA 92688

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    10,030 sqft

    Industrial warehouse featuring a fenced yard and major street frontage.

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    Rancho Santa Margarita Flex Space
    Rancho Santa Margarita Flex Space

    30302 Esperanza, Rancho Santa Margarita, CA 92688

    Contact for pricing
    5,583 sqft

    Flex space with offices, kitchen, fenced yard, and ample power.

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    Industrial Building with Gated Yard
    Industrial Building with Gated Yard

    30412 Esperanza, Rancho Santa Margarita, CA 92688

    Contact for pricing
    20,500 sqft

    Freestanding industrial building featuring office space and a gated yard.

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    Medical Office Condo Suite
    Medical Office Condo Suite

    30212 Tomas, Rancho Santa Margarita, CA 92688

    Contact for pricing
    1,620 sqft

    Condo medical office suite featuring six offices, a break room, and a conference room.

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    High-Image Flex Building For Rent
    High-Image Flex Building For Rent

    30191 Avenida De Las Banderas, Rancho Santa Margarita, CA 92688

    Contact for pricing
    23,849 sqft

    R&D/flex building in South Orange County business park.

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    Freestanding R&D Building For Lease
    Freestanding R&D Building For Lease

    22391 Gilberto, Rancho Santa Margarita, CA 92688

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    18,112 sqft

    Two-story R&D building with secured yard in South Orange County.

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    Warehouse with Ground-Level Loading
    Warehouse with Ground-Level Loading

    23141 Arroyo Vista, Rancho Santa Margarita, CA 92688

    Contact for pricing
    15,786 sqft

    First-floor warehouse space offers two 12x14 loading doors, fire sprinklers, and 22' clearance.

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    Restaurant Spaces in Rancho Santa Margarita
    Restaurant Spaces in Rancho Santa Margarita

    31431-31541 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

    Contact for pricing

    Restaurant spaces for lease in Rancho Santa Margarita shopping center.

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    Modern Flex Space Available
    Modern Flex Space Available

    22521 Avenida Empresa, Rancho Santa Margarita, CA 92688

    Contact for pricing

    Flex project in prime location with modern units.

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    Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 19 Active listings in Rancho Santa Margarita, CA, we suggest exploring alternatives. Similar 17 Properties for Sales.

    Similar Spaces for Sale in Rancho Santa Margarita, CA

    Consider Similar Space for Sale. We found 17 Spaces matching your search parameters.

    Corner Flex Space with Office
    Corner Flex Space with Office

    30394 Esperanza, Rancho Santa Margarita, CA 92688

    $2,750,000
    5,490 sqft

    Combines warehouse functionality with a dedicated office component.

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    Freestanding Medical Office Building For Sale
    Freestanding Medical Office Building For Sale

    29803 Santa Margarita Parkway, Rancho Santa Margarita, CA 92688

    $3,645,600
    6,076 sqft

    Single-story medical office building with Santa Barbara style architecture.

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    Flex Space with Warehouse Clearance
    Flex Space with Warehouse Clearance

    30012 Aventura, Rancho Santa Margarita, CA 92688

    Contact for pricing
    3,865 sqft 0.55 AC lot

    Business park property combining office, warehouse, and a possible fenced yard area.

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    Owner-User Medical Office Building
    Owner-User Medical Office Building

    22331 El Paseo, Rancho Santa Margarita, CA 92688

    $10,978,000
    22,000 sqft 1.67 AC lot

    22,000-SF owner-user building on a corner lot with permitted medical, retail, and office uses.

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    Rancho Santa Margarita Industrial Property
    Rancho Santa Margarita Industrial Property

    22412 Gilberto, Rancho Santa Margarita, CA 92688

    $6,417,915
    16,085 sqft

    Industrial property available for sale in Rancho Santa Margarita.

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    Rancho Santa Margarita, CA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Rancho Santa Margarita, CA with 19 listings featured on our commercial real estate exchange. The current inventory includes 421,517 square feet of properties with an estimated lease value of $16,655.

    Estimated lease rates for Commercial real estate in Rancho Santa Margarita, CA begin at $129/Mo, with an average of $5,551/Mo and extend to $16,026/Mo.
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    Most Searched ZIP Codes in Rancho Santa Margarita, CA

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