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    South Carolina Office Buildings for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    170 results
    Adaptable Office Space in Florence
    $4,200/Mo
    3,600 SF

    Adaptable Office Space in Florence

    720 S Coit St, Florence, SC 29501

    Well-located office building for lease in a desirable professional location.

    • Prime location directly across from Timrod Park and minutes from downtown Florence.
    • Functional layout with multiple private offices, meeting room, and reception area.
    • Ample on‑site parking for employees and visitors.
    • Classic architectural character, hardwood floors, and abundant natural light.
    • Full kitchen and basement storage.
    Updated: Apr 1
    View details
    Versatile Commercial Building in Warrenville
    $7,000/Mo
    9,000 SF

    Versatile Commercial Building in Warrenville

    1089 Augusta Road, Warrenville, SC 29851

    Two-story commercial building with 9,000 SF available for lease.

    • Over 18,000 SF free‑standing commercial building with approximately 9,000 SF immediately available, suitable for diverse uses.
    • Ample on‑site parking with over 50 spaces.
    • Excellent visibility on a corridor with 5,600 vehicles per day.
    • Includes existing security system with surveillance cameras and coded keypad entry, plus CAT6 IT infrastructure.
    • Convenient location: 10 minutes from downtown Aiken and 20 minutes from North Augusta, across from Warren Mill Lofts.
    Updated: Apr 16
    View details
    Versatile Commercial Building in Warrenville
    $7,000/Mo
    9,000 SF

    Versatile Commercial Building in Warrenville

    Two-story commercial building with 9,000 SF available for lease.

    1089 Augusta Road, Warrenville, SC 29851
    View details
    Free-Standing Brick Office Building
    $1,950/Mo
    1,494 SF

    Free-Standing Brick Office Building

    Brick office building near downtown Aiken and Interstate 20.

    1598 Columbia Highway, Aiken, SC 29801
    View details
    Aiken Commercial Office Building
    $4,325/Mo
    2,595 SF

    Aiken Commercial Office Building

    Professional office space in a convenient, accessible Aiken location.

    160 Waterloo Street SW, Aiken, SC 29801
    View details
    Free-Standing Brick Office Building
    $1,950/Mo
    1,494 SF

    Free-Standing Brick Office Building

    Charming office building near downtown Aiken and Interstate 20.

    1598 Columbia Highway N, Aiken, SC 29801
    View details
    Professional Office Building in Myrtle Beach
    $5,000/Mo
    2,230 SF

    Professional Office Building in Myrtle Beach

    Well-maintained office building in the heart of Myrtle Beach.

    607 19th Ave. N, Myrtle Beach, SC 29577
    View details
    Secure Aiken Office Building For Rent
    $11,000/Mo
    7,000 SF

    Secure Aiken Office Building For Rent

    Move-in ready office building near Aiken Bypass with ample parking.

    900 Trail Ridge Road, Aiken, SC 29803
    View details
    Charming Historic Office Building Rental
    $4,200/Mo
    3,000 SF

    Charming Historic Office Building Rental

    Office building for rent across from Timrod Park.

    720 S Coit St., Florence, SC 29501
    View details
    Class A Office Building
    $24,000 SF/Yr
    12,000 SF

    Class A Office Building

    Class A office building near amenities, tenants in place.

    601 21st Ave. N, Myrtle Beach, SC 29577
    View details
    Medical/Professional Office Near Conway Hospital
    $6,251/Mo
    5,246 SF

    Medical/Professional Office Near Conway Hospital

    Medical/professional office building near Conway Medical Center with customizable space.

    8028 Myrtle Trace Dr., Conway, SC 29526
    View details
    Remodeled Office Building For Rent
    $1,800/Mo
    1,874 SF

    Remodeled Office Building For Rent

    Remodeled office building with high traffic count in Dillon, SC.

    1013 N Highway 301, Dillon, SC 29536
    View details
    New Custom-Built Office Suites
    $1,500/Mo

    New Custom-Built Office Suites

    Pre-leasing custom office suites with private entrances, available Q2 2026.

    101, Ladys Island, SC 29907
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    Aiken Office Building For Lease
    $11,000/Mo
    7,000 SF

    Aiken Office Building For Lease

    Secure office building near Aiken Bypass, move-in ready condition.

    900 Trail Ridge Road unit: 2Nd Floor, Aiken, SC 29803
    View details
    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF

    Reimagined Class-A Office Space

    Newly renovated office space in prime downtown location.

    1710 Gervais St., Columbia, SC 29201
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    Class A Office Building
    $28 SF/Yr
    8,209 SF

    Class A Office Building

    New Class A office space available for lease in Myrtle Beach.

    1103 48th Avenue North, Myrtle Beach, SC 29577
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    Class A Office Space
    $615/Mo

    Class A Office Space

    Class A office suites for lease in North Myrtle Beach.

    1016 2nd Avenue North, North Myrtle Beach, SC 29582
    View details
    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF

    Two-Story Office Building For Rent

    Two-story office building with flexible layout in central Columbia.

    123 Lawand Dr, Columbia, SC 29210
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    Modern Office Space Available
    $500/Mo

    Modern Office Space Available

    Updated office space with 9 offices, conference room, and breakroom.

    521 N Mcduffie St, Anderson, SC 29621
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    Class A Office Space Available
    $550/Mo

    Class A Office Space Available

    Class A office building in Myrtle Beach's business district.

    2411 N. Oak Street, Myrtle Beach, SC 29577
    View details
    Class A Office Space
    $45 SF/Yr
    5,024 SF

    Class A Office Space

    Premier office space in Greenville's award-winning downtown.

    110 East Court Street, Greenville, SC 29601
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    Class A Medical Office Building
    $28 SF/Yr
    14,084 SF

    Class A Medical Office Building

    Renovated medical/office building with ample parking in Mt. Pleasant.

    1200 Innovation Way, Mount Pleasant, SC 29466
    View details
    Class A Office Space Available
    $34 SF/Yr
    8,452 SF

    Class A Office Space Available

    Four-story, 102,024 SF Class A office building for lease.

    4401 Leeds Avenue, North Charleston, SC 29405
    View details
    Class A Office Space
    $43 SF/Yr
    9,675 SF

    Class A Office Space

    Multi-tenant office building in Charleston's Historic District.

    100 Calhoun Street, Charleston, SC 29401
    View details

    South Carolina Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in South Carolina with 170 listings featured on our commercial real estate exchange. The current inventory includes 47,325,030,190 square feet of properties with an estimated lease value of $1,109 /Mo.

    Estimated lease rates for Office buildings in South Carolina begin at $5 SF/Yr, with an average of $22 SF/Yr and extend to $45 SF/Yr.
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