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    South Carolina Office Buildings for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    168 results
    Office Building with Private Offices
    $2,900/Mo
    3,100 SF
    Office Building with Private Offices

    720 S Coit St, Florence, SC 29501

    Functional office layout with hardwood floors, meeting room, kitchen, basement storage, and on-site parking for client-facing operations.
    • +/-3,600 SF office building for lease with a functional layout and multiple private offices
    • Dedicated meeting room plus receptionist area for client‑facing operations
    • Classic interior character with hardwood floors and carpet flooring; abundant natural light
    • Heat pump heating and central air conditioning
    • Full kitchen and basement with additional storage; covered rear area for extra storage or utility use
    Updated: May 6
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    Sound-Proof Executive Office Building
    $4,800/Mo
    3,214 SF
    Sound-Proof Executive Office Building

    212 Newberry Street NW, Aiken, SC 29801

    Single-story office with executive offices, conference rooms, and private paved parking for professional tenants.
    • Single‑story professional office building with approx. 3,198 gross leasable square feet (GLSF)
    • Downtown Aiken location with private asphalt paved on‑site parking lot
    • Layout includes five executive offices, two conference rooms, and lobby with restroom
    • Break room with restroom and shower plus file/copy area
    • Sound‑proof individual offices originally designed as an attorney’s office for professional uses
    Updated: Jun 1
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    Versatile Commercial Building in Warrenville
    $7,000/Mo
    9,000 SF
    Versatile Commercial Building in Warrenville

    Two-story commercial building with 9,000 SF available for lease.

    1089 Augusta Road, Warrenville, SC 29851

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    Free-Standing Brick Office Building
    $1,950/Mo
    1,494 SF
    Free-Standing Brick Office Building

    Charming office building near downtown Aiken and Interstate 20.

    1598 Columbia Highway, Aiken, SC 29801

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    Secure Aiken Office Building Available
    $11,000/Mo
    7,000 SF
    Secure Aiken Office Building Available

    Move-in ready office building near Aiken Bypass with ample parking.

    900 Trail Ridge Road, Aiken, SC 29803

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    Versatile Commercial Building For Lease
    $7,000/Mo
    9,000 SF
    Versatile Commercial Building For Lease

    Two-story commercial building with 9,000 SF available for lease.

    1089 Augusta Road, Warrenville, SC 29851

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    Free-Standing Brick Office Building
    $1,950/Mo
    1,494 SF
    Free-Standing Brick Office Building

    Charming office building near downtown Aiken and Interstate 20.

    1598 Columbia Highway N, Aiken, SC 29801

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    Professional Office Building in Myrtle Beach
    $5,000/Mo
    2,230 SF
    Professional Office Building in Myrtle Beach

    Well-maintained office building in the heart of Myrtle Beach.

    607 19th Ave. N, Myrtle Beach, SC 29577

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    Aiken Office Building For Lease
    $11,000/Mo
    7,000 SF
    Aiken Office Building For Lease

    Secure office building near Aiken Bypass, move-in ready condition.

    900 Trail Ridge Road, Aiken, SC 29803

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    Aiken Commercial Office Building
    $4,325/Mo
    2,595 SF
    Aiken Commercial Office Building

    Professional office space in a convenient, accessible Aiken location.

    160 Waterloo Street SW, Aiken, SC 29801

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    Main Street Office Space Available
    $3,400/Mo
    23,000 SF
    Main Street Office Space Available

    2800 SF Class A office space for rent.

    2315 N Main Street, Anderson, SC 29621

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    Class A Office Building
    $24,000 SF/Yr
    12,000 SF
    Class A Office Building

    Office building near amenities, tenants in place until 2027.

    601 21st Ave. N, Myrtle Beach, SC 29577

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    Well-Maintained Building on Silver Bluff
    $9,984/Mo
    5,705 SF
    Well-Maintained Building on Silver Bluff

    Flexible 5,705 SF building on 1.17 acres for rent.

    190 Crepe Myrtle Court, Aiken, SC 29803

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    New Retail Spaces in Development
    $6,082/Mo
    2,500 SF
    New Retail Spaces in Development

    New retail spaces for lease in Pawleys Island, SC.

    9601 Ocean Highway, Pawleys Island, SC 29585

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    Reimagined Class-A Office Space
    $25 SF/Yr
    7,521 SF
    Reimagined Class-A Office Space

    Newly renovated office space in prime downtown location.

    1710 Gervais St., Columbia, SC 29201

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    Mixed-Use Building with Storefronts
    $35 SF/Yr
    10,673 SF
    Mixed-Use Building with Storefronts

    Three-story historic building offers flexible space for retail, office, or hospitality with on-site parking and outdoor access.

    438 King St, Charleston, SC 29403

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    Ashley Riverview Center Office Space
    $27 SF/Yr
    10,092 SF
    Ashley Riverview Center Office Space

    Multi-tenant office building with Ashley River views and easy access.

    4401 Belle Oaks Dr, North Charleston, SC 29405

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    Class A Office Building
    $28 SF/Yr
    8,209 SF
    Class A Office Building

    New Class A office space available for lease in Myrtle Beach.

    1103 48th Avenue North, Myrtle Beach, SC 29577

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    Premier Greenville Office Complex
    $19 SF/Yr
    1,422 SF
    Premier Greenville Office Complex

    Variety of office spaces with extensive upgrades and easy access.

    37 Villa Rd, Greenville, SC 29615

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    Professional Office Space For Rent
    $895/Mo
    Professional Office Space For Rent

    Prime location office building with walkable access to local favorites.

    845 Lowcountry Blvd, Mount Pleasant, SC 29464

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    Two-Story Office Building For Rent
    $16 SF/Yr
    3,960 SF
    Two-Story Office Building For Rent

    Two-story office building with flexible layout in central Columbia.

    123 Lawand Dr, Columbia, SC 29210

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    Class A Office Space
    $37 SF/Yr
    5,153 SF
    Class A Office Space

    Class A office space in downtown Charleston for lease.

    40 Calhoun Street, Charleston, SC 29401

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    Class A Office Space
    $45 SF/Yr
    5,024 SF
    Class A Office Space

    Premier office space in Greenville's award-winning downtown.

    110 East Court Street, Greenville, SC 29601

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    Office Property Near Downtown Columbia
    $17 SF/Yr
    8,181 SF
    Office Property Near Downtown Columbia

    Office and flex spaces available near I-20 and I-26.

    720 Gracern Rd, Columbia, SC

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    South Carolina Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in South Carolina with 168 listings featured on our commercial real estate exchange. The current inventory includes 2,756,316 square feet of properties with an estimated lease value of $11,166,400.

    Estimated lease rates for Office buildings in South Carolina begin at $1.77 SF/Yr, with an average of $110,558 and extend to $8,250,000.
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