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    South Carolina Office Buildings for Lease

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    Greenville, SC Columbia, SC Charleston, SC Myrtle Beach, SC North Charleston, SC Spartanburg, SC Rock Hill, SC Mount Pleasant, SC
    178 properties
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    Nine-Room Office Building
    Updated: Oct 8
    Nine-Room Office Building

    118 Park Avenue SE, Aiken, SC 29801

    $2,800/Mo
    2,522 sqft 0.02 AC lot
    2,522 square feet with nine rooms and two bathrooms
    Built in 1975; vinyl siding and wood‑frame construction
    Central air; forced‑air heating with electric and natural gas
    Off‑street parking
    Downtown Aiken, across from the Aiken Courthouse and next to TD Bank
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    Office Building Near City Center
    Updated: Sep 5
    Office Building Near City Center

    129 S Coit Street, Florence, SC 29501

    $1,400/Mo
    1,320 sqft
    1,320‑square‑foot office building
    Adjacent to City Center
    Built in 1959
    129 S Coit Street, Florence, SC 29501
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    Remodeled Brick Office Building
    Remodeled Brick Office Building

    1013 N Highway 301, Dillon, SC 29536

    $1,500/Mo
    1,874 sqft

    Flexible office layout with private rooms, reception space, a kitchen, and on-site parking.

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    Medical Office Space with Clinical Upfit
    Medical Office Space with Clinical Upfit

    2320 Cosgrove Avenue, North Charleston, SC 29405

    $24 SF/Yr
    4,935 sqft 0.31 AC lot

    Plumbing and medical connections remain throughout the building, alongside on-site parking.

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    Freestanding Brick Office Building
    Freestanding Brick Office Building

    1598 Columbia Highway, Aiken, SC 29801

    $1,800/Mo
    1,494 sqft 0.83 AC lot

    Five offices accompany a conference room, kitchen and break area, data room, and storage.

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    Freestanding Brick Office Building
    Freestanding Brick Office Building

    1598 Columbia Highway N, Aiken, SC 29801

    $1,800/Mo
    1,494 sqft

    Five private offices accompany a conference room, break area, data room, and accessible restroom.

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    Standalone Office Building
    Standalone Office Building

    607 19th Ave. N, Myrtle Beach, SC 29577

    $4,750/Mo
    2,230 sqft 0.22 AC lot

    Multi-office layout with conference space, reception, kitchen breakroom, private restrooms, and a security system.

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    Free-Standing Two-Story Office Building
    Free-Standing Two-Story Office Building

    1089 Augusta Rd, Warrenville, SC 29851

    $7,000/Mo
    9,000 sqft 2.50 AC lot

    Well-maintained two-story office building with security system, CAT6 infrastructure, and ample on-site parking.

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    Class A Office Building
    Class A Office Building

    601 21st Ave. N, Myrtle Beach, SC 29577

    $24,000/Mo
    12,000 sqft 1.04 AC lot

    12,000-square-foot office property with elevator access and tenants in place through March 2027.

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    Renovated Office Building
    Renovated Office Building

    812 W Whitner Street, Anderson, SC 29624

    $3,500/Mo
    0.76 AC lot

    A converted historic residence provides private offices, hardwood flooring, and substantial on-site parking.

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    Renovated Stand-Alone Office Building
    Renovated Stand-Alone Office Building

    725 East Martintown Road, North Augusta, SC 29841

    $16 SF/Yr
    2,822 sqft

    Flexible office layout with private rooms, meeting space, a breakroom, and dual-road access.

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    Office Building with Drive-Through
    Office Building with Drive-Through

    190 Crepe Myrtle Court, Aiken, SC 29803

    $9,984/Mo
    5,705 sqft 1.17 AC lot

    Flexible commercial building with multiple entrances, zoned HVAC, backup power, and a tenant-ready layout for office or retail use.

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    Renovated Office Building
    Renovated Office Building

    38 New Orleans Road, Hilton Head Island, SC 29928

    $18 SF/Yr
    0.41 AC lot

    The building offers multiple offices, central HVAC, public water, and public sewer.

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    Single-Story Freestanding Office Building
    Single-Story Freestanding Office Building

    1313A Miller Road, Greenville, SC 29607

    $16.50 SF/Yr
    4,000 sqft

    Functional single-story office layout with multiple private offices, open bullpen space, conference room, and on-site parking.

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    Single-Story Professional Office
    Single-Story Professional Office

    212 Newberry St NW, Aiken, SC 29801

    $4,800/Mo
    3,214 sqft

    Single-story office building with executive offices, conference rooms, and private on-site parking.

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    Freestanding Brick Office Building
    Freestanding Brick Office Building

    1598 Columbia Hwy, Aiken, SC 29801

    $1,800/Mo
    1,494 sqft

    Single-story office property with five offices, a conference room, and dedicated support areas.

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    Office Building with Major Road Visibility
    Office Building with Major Road Visibility

    4995 Lacross Rd, North Charleston, SC 29406

    $3,047/Mo
    6,158 sqft

    Office space in Rivergate Center I with strong major-road visibility and ample on-site parking for tenants and visitors.

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    Freestanding Office Building
    Freestanding Office Building

    607 19th Ave. N, Myrtle Beach, SC 29577

    $4,750/Mo
    2,230 sqft

    Six-office configuration with a conference room, reception area, kitchen breakroom, and two bathrooms.

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    Updated Office Building with Elevators
    Updated Office Building with Elevators

    900 Trail Ridge Road 2nd Floor, Aiken, SC 29803

    $11,000/Mo
    7,000 sqft

    Full-service occupancy includes electricity, taxes, insurance, and other operating costs.

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    Turn-Key ADA Accessible Professional Office
    Turn-Key ADA Accessible Professional Office

    106 Memorial Dr, Greer, SC 29650

    $2,200/Mo
    1,442 sqft 0.32 AC lot

    Newly remodeled office with reception, three private offices, lounge, kitchen, and 10 on-site parking spaces.

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    Class A Office Building with Retail
    Class A Office Building with Retail

    3 Research Drive, Greenville, SC 29607

    $1,208/Mo
    1,208 sqft

    Class A office building on the CU-ICAR campus with a LEED Silver certification, plus a ground-floor retail/office suite.

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    Two-Story Office Building with Parking
    Two-Story Office Building with Parking

    1089 Augusta Road, Warrenville, SC 29851

    $7,000/Mo
    18,372 sqft 2.50 AC lot

    Well-maintained 2-story office building with extensive on-site parking and an additional 1,200 SF outbuilding.

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    Two-Building Office Medical Park
    Two-Building Office Medical Park

    3600 Forest Dr, Columbia, SC 29204

    $22 SF/Yr
    150,000 sqft

    Two office and medical buildings offer extensive parking and planned upgrades to common areas and facades.

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    Freestanding Office Building in Myrtle Beach
    Freestanding Office Building in Myrtle Beach

    1051 Shine Ave., Myrtle Beach, SC 29577

    $10,632/Mo
    6,379 sqft

    Office building in The Market Common District for rent.

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    South Carolina Office buildings Market Trends and Statistics

    Explore Office buildings leasing options in South Carolina with 178 listings featured on our commercial real estate exchange. The current inventory includes 3,183,729 square feet of properties with an estimated lease value of $1,402.

    Estimated lease rates for Office buildings in South Carolina begin at $5.94 SF/Yr, with an average of $22.99 SF/Yr and extend to $74.38 SF/Yr.
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