La Jolla, CA Mixed-use Properties for Sale

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Coronado, CA National City, CA Lemon Grove, CA Chula Vista, CA La Mesa, CA Bonita, CA Spring Valley, CA Imperial Beach, CA

35 properties

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Updated: Mar 11

Three-Story Mixed-Use Building

2368 2nd AVE, San Diego, CA 92101

$2,669,000

3,800 sqft 0.13 AC lot

3‑story mixed‑use building with approximately 3,800 square feet
0.1251‑acre parcel at 2368 2nd AVE, San Diego, CA 92101
Independent access to each floor supports separate occupancy or leasing
Mixed‑use zoning accommodates commercial and residential configurations
Mills Act property with tax benefits for qualified owners

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Updated: Jun 2

Upgraded Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,890,000

3,750 sqft 0.13 AC lot

Five‑unit configuration with one professional office and four residential units
3,750 square feet on a 0.1285‑acre parcel
Two residential units rebuilt from the ground up in 2024
Corner location at 1st Ave and Maple St with dual street frontage
New electrical, plumbing, insulation, HVAC, meters, and property‑wide fire sprinklers

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Mixed-Use Storefront Property

3275 Euclid, San Diego, CA 92105

$900,000

0.11 AC lot

Corner-lot commercial property with storefront space and separate entrances.

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See what stands out in San Diego County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Updated Mixed-Use Office-Retail Building

3675 Voltaire St, San Diego, CA 92106

$4,500,000

11,060 sqft

Retail space at grade is paired with offices above in a flexible commercial layout.

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Live-Work Space with Two Offices

2487 Kettner Blvd, San Diego, CA 92101

$1,149,000

1,610 sqft 0.02 AC lot

Commercially zoned property with two kitchens, an upgraded full bath, and mixed-use flexibility for office or residential use.

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Remodeled Mixed-Use Property

825-829 Washington St., San Diego, CA 92103

$1,189,000

1,778 sqft 0.03 AC lot

Three-unit office and retail property with updated building systems and finishes.

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Bankers Hill Mixed-Use Opportunity

2368 2nd Ave, San Diego, CA 92101

$2,669,000

3,800 sqft

Three-story mixed-use property in Bankers Hill near Balboa Park.

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Mixed-Use Property with Alley Access

1434-44 Garnet Ave, San Diego, CA 92109

$1,995,000

1,622 sqft 0.14 AC lot

Retail/office space includes a detached studio and rear open area.

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Four-Story Mixed-Use Building

920 Kline Street, La Jolla, CA 92037

$5,800,000

20,000 sqft 1.50 AC lot

Mixed retail and office occupancy is supported by an updated elevator and private baths in many suites.

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Corner-Lot Mixed-Use Building

2754 Imperial Avenue, San Diego, CA 92102

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4,272 sqft 0.13 AC lot

Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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Mixed-Use Property with Residence

4741 Point Loma Ave, San Diego, CA 92106

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3,376 sqft

Three-part configuration combines commercial suites with a two-level upper residence.

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Signalized Corner Mixed-Use Property

1075 ROSECRANS ST SAN DIEGO CA 92106-3044, San Diego, CA 92106

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4,209 sqft 0.22 AC lot

CC 4-2 zoning supports retail, office, residential, and hospitality applications.

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Single-Tenant Mixed-Use Building

2317 Hotel Circle South, San Diego, CA 92108

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9,240 sqft 1.86 AC lot

Two-story retail and office asset with CO-2-2 zoning and on-site parking.

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Freestanding Mixed-Use Lab Building

9955 Mesa Rim Rd, San Diego, CA 92121

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15,853 sqft 5.45 AC lot

Renovation plans include facade and landscaping upgrades, with warehouse and laboratory infrastructure already in place.

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Renovated Mixed-Use Portfolio

3131-57 Adams Avenue, San Diego, CA 92116

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7,520 sqft 0.35 AC lot

Two adjacent properties combine apartments, retail suites, and updated residential interiors.

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Mixed-Use Building with Residential Units

4702-4714 University Ave, San Diego, CA 92105

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11,517 sqft 0.45 AC lot

Mixed-use improvements include four vacant one-bedroom, one-bath residential units.

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Mixed-Use Investment in La Playa

1051-65 Rosecrans Street, San Diego, CA 92106

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7,600 sqft

Mixed-use property in Point Loma with retail and residential units.

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Mixed-Use Development Opportunity

2135 University Avenue, San Diego, CA 92104

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880 sqft

Current automotive repair shop in San Diego’s Transit Priority Zone, with plans outlined for retail below and multifamily above.

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Three-Building Mixed-Use Property

2329 India Street, San Diego, CA 92101

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4,274 sqft

Mixed-use offering with three separate buildings and on-site parking stalls for operational flexibility.

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Corner Lot with Development Potential

3665 Imperial Ave, San Diego, CA 92113

$624,000

0.14 AC lot

High-traffic corner lot suitable for commercial or residential development.

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Mixed-Use Building with Loft

1733-37 Adams Ave, San Diego, CA 92116

$1,200,000

Existing café space includes a grease trap and an upper-level loft.

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Downtown San Diego Mixed-Use Building

640 Broadway, San Diego, CA 92101

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29,096 sqft 0.23 AC lot

Mixed-use building in downtown San Diego with redevelopment potential.

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Remodeled Mixed-Use Property

110 Maple, San Diego, CA 92103

$4,890,000

3,750 sqft

Corner asset combining professional office space with four updated residential units and a shared landscaped courtyard.

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Mixed-Use Property with Retail Space

6780 La Jolla Boulevard, San Diego, CA 92037

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5,176 sqft

Three commercial spaces and two residential units occupy this coastal property near Windansea Beach.

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La Jolla, CA Mixed-Use Properties Market Trends and Statistics

Explore 35 mixed-use properties for sale in La Jolla, CA, showcased through 35 active listings on our real estate platform. These investment opportunities span a total of 215,452 square feet of properties for sale, with an estimated market value of $41,775,000.

Sale prices for multi use buildings in La Jolla, CA start at $624,000, averaging $2,785,000, and reaching up to $5,800,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 44K

Population Growth (5Y) -1.1%

Median Household Income $141,822

College Educated 80.1%

Taxes & Financing

Tax Rate (average for all types) 1.15%

Property Tax per SF $9.03 per SF

Tax Rate vs County Average 0.02 pp below county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Diego County

New Delisted

Total CRE Inventory on Market (SF)

Property Size Breakdown

The majority of commercial real estate listings in La Jolla fall within the 50,000 to 100,000 square foot range.

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