San Ysidro, CA Medical Office Space for Sale

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Updated: Apr 4

San Ysidro Mixed-Use Investment Opportunity

165 W San Ysidro Blvd, San Ysidro, CA 92173

$4,099,000

7,989 sqft 0.32 AC lot

Prime location: Just 1.5 miles from the world's busiest land border crossing.
New construction (2021) offers 7 units with 7,989 SF of rentable space.
Mixed‑use zoning (CC‑3‑4) provides flexible options for restaurants, medical offices, or professional services.
Benefit from 20 on‑site parking spaces.
Equipped with grease interceptors and elevator service.

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This listing looks promising.

Here's a quick look at some key insights for

165 W San Ysidro Blvd, San Ysidro, CA 92173

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Est. Cap Rate

4.7%
NOI ÷ price
Est. NOI

$193K
Annual
Mortgage

$2.4M
Apr 2025
Last Sold

Nov 2012
$950K
Property Type

Retail Stores
Built 2021

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Updated: Jul 6

Mixed-Use Corner Commercial Property

3275 Euclid, San Diego, CA 92105

$900,000

0.11 AC lot

Zoned CUPD‑CU‑1‑1 within San Diego’s Central Urbanized Planned District for a mixed‑use concept
1,380 SF property on a 4,802 SF corner lot along a high‑traffic transit corridor
Dual‑address identity: 3275 Euclid Ave & 4769 Thorn St, with separate entrances for business operations and residential/private access
Located in the protected Islenair Historic District (buyer to verify historic guidelines with the City of San Diego)
Commercial storefront on the property with street visibility for storefront signage

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Mixed-Use Property in Opportunity Zone

4170 Fairmount Ave, San Diego, CA 92105

$999,000

1,404 sqft

Mixed-use property with high foot traffic in City Heights.

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Ground-Floor Office Condo Suite

3740 Park Boulevard Cu1, San Diego, CA 92103

$2,100,000

2,360 sqft

Modern ground-floor office condo built in 2007 with private offices, reception, open work areas, and multiple entrances.

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La Jolla Multifamily/Medical Building

6628 La Jolla Blvd., San Diego, CA 92037

$2,800,000

Multifamily property with RM-7 zoning, suitable for medical building.

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Medical Office Condominium Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

$1,469,182

2,366 sqft 3.05 AC lot

Well-maintained four-story medical office building with upgraded interiors and common areas, positioned for healthcare operators.

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Mixed-Use Office and Retail Building

4116 W Point Loma Blvd, San Diego, CA 92110

$2,800,000

In-place office and retail property with a medical lease set to expire in January 2027.

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La Jolla Medical Office Building

San Diego, CA

$8,500,000

7,077 sqft 0.31 AC lot

Multi-tenant medical office building in La Jolla's commercial district.

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Prime Hillcrest Retail Opportunity

535 Robinson Ave, San Diego, CA

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21,785 sqft 0.55 AC lot

High-density residential zoning in a vibrant urban core.

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Medical/Office Building For Sale

8933 Activity Rd, San Diego, CA

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36,731 sqft 1.84 AC lot

Mixed-use building suitable for owner-user or multiple tenants.

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Office/Medical Condominium Project in San Diego

5080-90 Shoreham Pl, San Diego, CA 92122

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6,549 sqft

Two-story office/medical condominium project in Governor Park, San Diego.

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Medical Office Suites For Sale

11717 Bernardo Plaza Ct, San Diego, CA 92128

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7,200 sqft

Modern, renovated medical office suites in Rancho Bernardo.

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San Diego Medical/Office Condo

5330 Carroll Canyon Rd, San Diego, CA 92121

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4,314 sqft

Spacious condo ideal for medical or office use.

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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 13 Active listings in San Ysidro, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Turnkey Medical Office Condo

890 EASTLAKE PKWY, Chula Vista, CA 91914

$750,000

Built-out pediatrics and family practice suite with exam rooms, reception, secure storage, and on-site parking.

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Turnkey Medical Office Condo

890 EASTLAKE PKWY 203, Chula Vista, CA 91914

$750,000

Medical office condo for sale, operating as pediatrics and family practice.

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Medical Office Corner Suite

15525 Pomerado Road, Suite C-5, Poway, CA 92064

$500,000

861 sqft

Second-floor corner suite with natural lighting and elevator service, adjacent to imaging and surgery center space.

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Renovated Medical/Professional Building For Sale

15644 Pomerado Rd, Poway, CA 92064

$855,000

1,368 sqft

Renovated medical/professional building near Pomerado Hospital with high visibility.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land Parcel

42079 Roick, Temecula, CA 92590

$1,249,000

1.23 AC lot

Commercially zoned land in Temecula provides a straightforward platform for future development plans.

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Murrieta Land Near Medical Center

28330 Joan Dunn Lane, Murrieta, CA 92563

$1,690,700

1,952 sqft 2.65 AC lot

2.65-acre vacant land parcel near Loma Linda University Medical Center.

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High-Frontage General Commercial Land

70265 Hwy 111, Rancho Mirage, CA 92270

$3,600,000

Finished highway frontage along a major corridor offers flexible options under C-G zoning for a variety of commercial uses.

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Commercial Land Parcel, C-G Zoned

70265 Hwy 111, Rancho Mirage, CA 92270

$3,600,000

4.72 AC lot

C-G zoned commercial land offering development flexibility near Hwy 111 in Rancho Mirage.

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San Ysidro, CA Medical Office Space Market Trends and Statistics

Explore 13 medical office space for sale in San Ysidro, CA, showcased through 13 active listings on our real estate platform. These investment opportunities span a total of 21,196 square feet of properties for sale, with an estimated market value of $17,167,182.

Sale prices for medical spaces in San Ysidro, CA start at $999,000, averaging $3,433,436, and reaching up to $8,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 27K

Population Growth (5Y) -16.8%

Median Household Income $65,865

College Educated 7.2%

High-Yield Neighborhoods for Investment

Identify San Ysidro submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood	Average Price
92173	$4.1M

Taxes & Financing

Tax Rate (average for all types) 0.94%

Property Tax per SF $14.23 per SF

Tax Rate vs County Average 0.24 pp below county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Diego County

New Delisted

Total CRE Inventory on Market (SF)

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