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    Durham County, NC Medical Offices for Lease

    8 results
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    Prime Medical Office Space Available
    Pending
    $18 SF/Yr
    2,312 SF

    Prime Medical Office Space Available

    2609 N Duke St Unit Bldg 300, Durham, NC 27704

    Versatile medical/office space in Durham's thriving North Duke corridor.

    • Prime medical/office space in a highly sought‑after location on Durham's North Duke Street corridor.
    • Excellent visibility and easy access to major roads and highways.
    • Dedicated parking with ample spaces for clients and staff.
    • Versatile space ideal for medical, dental, or general office use.
    • Includes reception area, private offices, conference rooms, and ADA‑compliant restrooms.
    Updated: Jul 30, 2025
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    Durham Medical Office Condos for Lease
    Contact for pricing
    41,558 SF

    Durham Medical Office Condos for Lease

    4020 Roxboro St, Durham, NC 27704

    Modern medical suites, North Durham, NC

    • Three suites available for lease.
    • Ample parking with a 6:1000 ratio.
    • Building and monument signage opportunities available.
    • Features a new HVAC system and newly paved parking lot.
    • Renovated common areas including corridors and restrooms.
    Updated: Dec 11, 2024
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    Durham Medical Office Suite for Lease/Sale
    Contact for pricing
    3,037 SF

    Durham Medical Office Suite for Lease/Sale

    Prime Durham medical office space available.

    249 Nc Highway 54, Durham, NC 27713
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    Madison Centre Executive Suites
    $26 SF/Yr
    9,992 SF

    Madison Centre Executive Suites

    Durham Office Space, 1,000 SF Available

    1804 Martin Luther King Jr Pkwy, Durham, NC 27707
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    Durham Medical/Office Building for Lease
    $23 SF/Yr
    4,769 SF

    Durham Medical/Office Building for Lease

    Freestanding 4,769 SF building suitable for medical or office use.

    110 E Carver St, Durham, NC 27704
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    Office/Medical Building Near Southpoint Mall
    $26 SF/Yr
    18,395 SF

    Office/Medical Building Near Southpoint Mall

    Single-story office/medical building near Southpoint Mall available for lease.

    5501 Fortunes Ridge Dr, Durham, NC 27713
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    Medical Office Space in Durham
    $23 SF/Yr
    5,986 SF

    Medical Office Space in Durham

    Dental specialist office space for lease near Duke University/Hospital.

    1212 Broad St, Durham, NC 27705
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    Class A Office Space
    $23 SF/Yr
    79,440 SF

    Class A Office Space

    Class A office space for lease in North Durham.

    4321 Medical Park Dr, Durham, NC 27704
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    Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 8 Active listings in Durham County, NC, we suggest exploring alternatives. Similar 7 Properties for Sales.

    Explore Similar Spaces for Sale in Durham County, NC

    Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF

    Colonial Square Office/Medical Building

    Multi-functional commercial building in Durham's Independence Park.

    4400 Ben Franklin Blvd, Durham, NC 27704
    View details
    Durham Office Near Highway 85
    $750,000
    1,600 SF

    Durham Office Near Highway 85

    Office property close to Highway 85, Duke, and RTP.

    3219 Guess Rd, Durham, NC 27705
    View details
    Southpoint Medical Office Investment
    $2,995,000
    8,986 SF

    Southpoint Medical Office Investment

    Durham, NC Medical Office Building - High Occupancy

    249 Nc Hwy 54- –, Durham, NC 27713
    View details
    Durham Medical Office Condo
    $850,000
    3,037 SF

    Durham Medical Office Condo

    Prime Medical Space, 3,037 SF, $850K

    249 Nc Highway 54, Durham, NC 27713
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    Durham Medical Office Condos
    Contact for pricing
    41,588 SF

    Durham Medical Office Condos

    Three Class A condos, 2024 renovation

    4020 Roxboro St, Durham, NC 27704
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    Morrisville Office Building - Class A
    Contact for pricing
    35,350 SF

    Morrisville Office Building - Class A

    35,350 SF Office, Prime Location, Vacant

    703 Slater Rd, Morrisville, NC 27560
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    Hayti District Office Complex
    $8,000,000
    9,000 SF

    Hayti District Office Complex

    Prime Durham location, 9,000 sq ft, vacant.

    601 Fayetteville St, Durham, NC 27701
    View details

    Durham County, NC Medical offices Leasing Opportunities Market Analysis

    Explore Medical offices leasing options in Durham County, NC with 15 listings featured on our commercial real estate exchange. The current inventory includes 5,266,142,640 square feet of properties with an estimated lease value of $139 SF/Yr.

    Estimated lease rates for Medical offices in Durham County, NC begin at $18 SF/Yr, with an average of $23 SF/Yr and extend to $26 SF/Yr.
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    Medical offices by market

    Browse Medical offices for Lease Near Durham, NC

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