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    Durham County, NC Medical Office Space for Sale

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    Road-Front Office Live-Work Unit
    Updated: Apr 30, 2025
    Road-Front Office Live-Work Unit

    3219 Guess Road Unit 3219, Durham, NC 27705

    $750,000
    1,600 sqft 0.50 AC lot
    Office unit on a half‑acre lot with road frontage on busy Guess Road in Durham
    Convenient access to Hwy 85, Duke, RTP, and major shopping centers
    Central air conditioning
    Heating: 3 (type not specified)
    35x20 lot dimensions with asphalt and a clear lot
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    This listing looks promising.

    Here's a quick look at some key insights for

    3219 Guess Road Unit 3219, Durham, NC 27705

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    • Est. Cap Rate

      3.3%
      NOI ÷ price

    • Est. NOI

      $25K
      Annual

    • Price @ 7% Cap

      $353K
      Suggested

    • Property Type

      Single Family Residence
      Built 1937
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    Two-Story Office Building
    Updated: Jun 19
    Two-Story Office Building

    3621 Lyckan Parkway, Durham, NC 27707

    Contact for pricing
    12,000 sqft
    12,000 SF, two‑story office building in Durham, North Carolina (Year built: 2004).
    Offered in partial shell condition with key infrastructure already in place for interior build‑outs.
    Interior can be customized for office or medical uses, including medical conversion suitability.
    Supports a range of professional uses such as primary care, specialty medical, dental, and professional service firms.
    Ample parking and layout intended for medical conversion.
    View details
    Medical Office & Wellness Center
    Medical Office & Wellness Center

    3017 Pickett Rd, Durham, NC 27705

    Contact for pricing
    25,317 sqft

    Medical office and wellness center in high-traffic Durham location.

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    Durham Office Near Highway 85
    Durham Office Near Highway 85

    3219 Guess, Durham, NC 27705

    $750,000
    1,600 sqft

    Office property close to Highway 85, Duke, and RTP.

    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Two-Story Standalone Office Condo
    Two-Story Standalone Office Condo

    2741 Campus Walk Ave, Durham, NC 27705

    Contact for pricing
    3,652 sqft

    Brand-new cold dark shell office condo with ample natural light and space up to 1,826 SF per floor.

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    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 5 Active listings in Durham County, NC, we suggest exploring several alternatives: similar 9 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Zoned Highway Business
    Commercial Land Zoned Highway Business

    1495 Concord Church Road, Creedmoor, NC 27522

    $369,900
    1.05 AC lot

    1.0462-acre vacant lot with HB zoning, public utilities, and about 275 feet of road frontage on E. Lyon Station Road.

    View details
    High Growth Area Land Opportunity
    High Growth Area Land Opportunity

    1200 Granite Falls, Rolesville, NC 27587

    $1,390,000

    Land suitable for medical offices, daycare, senior living, multi-family.

    View details
    Office & Institutional Zoning Lot
    Office & Institutional Zoning Lot

    College Street, Oxford, NC 27565

    $150,000
    0.65 AC lot

    Cleared commercial lot with O&I zoning and 95 feet of road frontage on College St (Hwy 15).

    View details
    Corner Commercial Land
    Corner Commercial Land

    629 W Academy Street, Fuquay Varina NC 27526, Fuquay Varina, NC 27526

    $950,000
    1.44 AC lot

    1.44-acre corner site zoned NC-CZD with all utilities on-site, positioned at Judd Parkway and NC Hwy 42.

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    Off-Market Properties in Durham County, NC

    Consider similar Off-Market properties in Durham County, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3026 Old Chapel Hill Rd
    Medical Office Space

    3026 Old Chapel Hill Rd, Durham, NC 27707

    Value Estimation by Request
    3,935 sqft
    View details
    703 Slater Rd
    Medical Office Space

    703 Slater Rd, Morrisville, NC 27560

    Value Estimation by Request
    35,350 sqft 2.89 AC lot
    View details
    5306-102 Hwy
    Medical Office Space

    5306-102 Hwy, Durham, NC 27713

    Value Estimation by Request
    2,028 sqft
    View details
    249 Nc Hwy 54- –
    Medical Office Space

    249 Nc Hwy 54- –, Durham, NC 27713

    Value Estimation by Request
    8,986 sqft
    View details
    5915 Farrington Rd
    Medical Office Space

    5915 Farrington Rd, Chapel Hill, NC 27517

    Value Estimation by Request
    5,622 sqft 1.39 AC lot
    View details
    249 Nc Highway 54
    Medical Office Space

    249 Nc Highway 54, Durham, NC 27713

    Value Estimation by Request
    3,037 sqft
    View details
    1804 Martin Luther King Jr Pkwy
    Medical Office Space

    1804 Martin Luther King Jr Pkwy, Durham, NC 27707

    Value Estimation by Request
    9,992 sqft 2.53 AC lot
    View details
    4210 Roxboro St
    Medical Office Space

    4210 Roxboro St, Durham, NC 27704

    Value Estimation by Request
    2,408 sqft
    View details
    249 Nc Highway 54
    Medical Office Space

    249 Nc Highway 54, Durham, NC 27713

    Value Estimation by Request
    3,037 sqft
    View details

    Durham County, NC Medical Office Space Market Trends and Statistics

    Explore 14 medical office space for sale in Durham County, NC, showcased through 5 active listings on our real estate platform. These investment opportunities span a total of 44,169 square feet of properties for sale, with an estimated market value of $1,500,000.

    Sale prices for medical spaces in Durham County, NC average $750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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