Advertise
    North Carolina
    Office

    Durham County, NC Office Spaces for Lease

    Notify Me
    List
    Map
    Charlotte, NC Raleigh, NC Fayetteville, NC Greensboro, NC Asheville, NC Jacksonville, NC Wilmington, NC Durham, NC
    Found 64 office spaces for lease in Durham County, NC, averaging $36/sq ft/yr. Use lease type data to compare options faster.
    Sort:
    NC, Durham - 3511 Shannon Road
    View details
    Office Units with Shared Common Area
    Updated: Jun 29
    Office Units with Shared Common Area

    3201 Yorktown Avenue, Durham, NC 27713

    $350/Mo
    907 sqft 1.55 AC lot
    907 square feet of office space
    Private office rooms with shared common area
    24‑hour access
    Wi‑Fi and utilities included
    Located near the Research Triangle Park, Downtown Durham, and highways
    View details
    Medical Office Space with Reception Area
    Updated: Dec 4, 2024
    Medical Office Space with Reception Area

    2609 N Duke Street, Durham, NC 27704

    $18 SF/Yr
    2,312 sqft 0.01 AC lot
    2,312 square feet of medical office space
    Reception area, private offices, conference rooms, and exam rooms
    ADA‑compliant restrooms
    Dedicated parking for clients and staff
    Built in 1978
    View details
    First-Floor Office Units
    First-Floor Office Units

    1906 Carolina 54, Durham, NC 27713

    $45,045/Mo
    2,145 sqft 1.02 AC lot

    Eight private offices, conference space, and updated finishes support a range of professional office arrangements.

    View details
    Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!
    Serviced Office Space for Rent at NC, Durham - Spaces Mangum Street. Contact us today to book a tour!

    555 Mangum St, Unit 100, Durham, NC 27701

    16 available spaces from 11 to 2,612 sqft
    $129-$54,775/Mo per office

    Find fully flexible work and meeting space in NC, Durham - Spaces Mangum Street. Book a tour & get info

    View details
    Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!
    Serviced Office Space for Rent at RTP Imperial. Contact us today to book a tour!

    4819 Emperor Blvd, Unit 400, Durham, NC 27703

    16 available spaces from 11 to 1,965 sqft
    $129-$13,893/Mo per office

    Flexible workspace in RTP Imperial. Book a tour & get info

    View details
    First-Floor Office Unit
    First-Floor Office Unit

    3604 Shannon Road Ste 105, Durham, NC 27707

    $900/Mo
    2,115 sqft

    Furnished professional suite with six private offices, conference room, kitchenette, and two restrooms.

    View details
    Canterbury Hall Office Units
    Canterbury Hall Office Units

    4815 Emperor Blvd, Durham, NC 27703

    $27.50 SF/Yr
    2,682 sqft

    Office availability at Canterbury Hall supports a range of space requirements in Durham.

    View details
    Carlisle Place Office Units
    Carlisle Place Office Units

    4721 Emperor Blvd, Durham, NC 27703

    $29.50 SF/Yr
    3,666 sqft

    Lease opportunity for office users at a named commercial property in Durham.

    View details
    Private-Office Coworking Space
    Private-Office Coworking Space

    3201 Yorktown Avenue Ste 117, Durham, NC 27713

    $350/Mo per office
    907 sqft

    Flexible workspace combines enclosed offices with shared common areas and round-the-clock access.

    View details
    Oxford Place Office Units
    Oxford Place Office Units

    1005 Slater Rd, Durham, NC 27703

    $27.50 SF/Yr
    1,476 sqft

    Lease opportunity for office accommodations at Oxford Place in Durham, North Carolina.

    View details
    Chelsea Place Office Units
    Chelsea Place Office Units

    1007 Slater Rd, Durham, NC 27703

    $27.50 SF/Yr
    1,494 sqft

    Lease opportunities are available within a named office property in Durham.

    View details
    Office Units
    Office Units

    4000 Sancar Way, Durham, NC 27713

    $29.50 SF/Yr
    1,332 sqft

    Office space is available across a broad range of suite sizes.

    View details
    Serviced Offices with Business Support at RTP Meridian. Contact us today to book a tour!
    Serviced Offices with Business Support at RTP Meridian. Contact us today to book a tour!

    2530 Floors, Durham, NC 27713

    16 available spaces from 11 to 2,015 sqft
    $119-$11,946/Mo per office

    Flexible workspace in RTP Meridian. Book a tour & get info

    View details
    Renovated Historic Building in Durham
    Renovated Historic Building in Durham

    733 Foster St, Durham, NC 27701

    $26.95 SF/Yr
    11,000 sqft

    Turn-key, furnished office suites in walkable downtown location.

    View details
    Move-In Ready Office Building
    Move-In Ready Office Building

    313 Foster St, Durham, NC 27701

    Contact for pricing
    4,125 sqft

    Two-story office building with six offices, conference rooms, patio, and a rear loading dock plus three parking spaces.

    View details
    Retail-Office Suite with Dedicated Parking
    Retail-Office Suite with Dedicated Parking

    600 Foster St, Durham, NC 27701

    Contact for pricing
    2,285 sqft

    Short-term suite with flexible use options, finished concrete floors, high ceilings, natural light, and dedicated parking.

    View details
    Main-Level Office Space
    Main-Level Office Space

    500 W Morgan St, Durham, NC 27701

    Contact for pricing
    4,101 sqft

    Access-controlled workspace combines private offices, open bullpen seating, and shared conference amenities in downtown Durham.

    View details
    Furnished Office Units
    Furnished Office Units

    101 Corcoran Street, Durham, NC 27701

    Contact for pricing
    48,860 sqft

    Flexible office availability includes private work areas, meeting rooms, collaboration zones, and shared break-room space.

    View details
    Move-In Ready Pediatric Medical Suite
    Move-In Ready Pediatric Medical Suite

    3400 Croasdaile Dr, Durham, NC 27705

    $25 SF/Yr

    First-floor medical office suite with private restrooms and a specialized ABA-focused upfit for a move-in ready pediatric practice.

    View details
    Multi-Size Office Units
    Multi-Size Office Units

    4170 Sancar Way, Research Triangle Park, NC 27709

    Contact for pricing
    30,000 sqft

    Office space is available for lease within Research Triangle Park.

    View details
    Miami North Office Units
    Miami North Office Units

    4506 S Miami Blvd, Durham, NC 27703

    Contact for pricing
    1,641 sqft

    Office suites are available within a named Durham business park building.

    View details
    Park Forty Plaza Office Units
    Park Forty Plaza Office Units

    1000 Park Forty Plz, Durham, NC 27713

    Contact for pricing
    1,411 sqft

    Office availability accommodates a range of suite sizes for lease.

    View details
    Office Suite with Executive Offices
    Office Suite with Executive Offices

    3710 University Dr, Durham, NC 27707

    Contact for pricing
    1,335 sqft

    Suite 302 offers a simple layout with five executive offices and an entry and waiting area.

    View details
    Creative Space with Loft Features
    Creative Space with Loft Features

    111 E. Chapel Hill St., Durham, NC 27701

    Contact for pricing
    2,312 sqft

    Historic building offers exposed brick, polished concrete, and abundant south-facing natural light.

    View details

    Durham County, NC Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Durham County, NC with 64 listings featured on our commercial real estate exchange. The current inventory includes 1,289,523 square feet of properties with an estimated lease value of $729.64.

    Estimated lease rates for Office Spaces in Durham County, NC begin at $4.63 SF/Yr, with an average of $36.48 SF/Yr and extend to $252 SF/Yr.
    List
    Map

    Office Spaces by market

    Browse Office Spaces for Lease Near Durham, NC

    Popular Categories

    Why this one?
    Saved
    Reason not saved — we won't ask again

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!