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    Durham County, NC Medical Office Space for Lease

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    6 properties
    Private Office Suite Space
    Updated: Jun 29
    Private Office Suite Space

    3201 Yorktown Avenue, Durham, NC 27713

    $350/Mo
    907 sqft
    Built in 1988
    Private office rooms with shared common area
    24‑hour access
    WiFi and utilities included
    Convenient location near RTP, Downtown, and highways
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    Prime Medical Office Space Available
    Updated: Dec 4, 2024
    Prime Medical Office Space Available

    2609 N Duke Street, Durham, NC 27704

    $18/Mo
    2,312 sqft
    Prime medical/office space in a highly sought‑after location on Durham's North Duke Street corridor.
    Excellent visibility and easy access to major roads and highways.
    Dedicated parking with ample spaces for clients and staff.
    Versatile space ideal for medical, dental, or general office use.
    Includes reception area, private offices, conference rooms, and ADA‑compliant restrooms.
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    CG-Zoned Commercial Space
    CG-Zoned Commercial Space

    2810 Hillsborough Road, Durham, NC 27705

    $18 SF/Yr
    2,978 sqft

    High-visibility commercial suite on Hillsborough Road with Commercial General zoning for a broad range of uses.

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    Roxboro Road Professional Office Space
    Roxboro Road Professional Office Space

    4210 N. Roxboro Street, Suite 140, Durham, NC 27704

    $20.50 SF/Yr
    2,408 sqft

    Office space ideal for professional services and medical offices.

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    South Durham Medical Office Space
    South Durham Medical Office Space

    415 W NC Hwy. 54, Durham, NC 27215

    Contact for pricing

    Medical office space in South Durham with ample parking.

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    Medical Office Space For Lease
    Medical Office Space For Lease

    4020 N Roxboro St, Durham, NC 27704

    Contact for pricing

    Second generation medical office space available for lease.

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    Based on your search, we've compiled 16 Potential Opportunities for your consideration. Besides 6 Active listings in Durham County, NC, we suggest exploring alternatives. Similar 6 Properties for Sales.

    Similar Spaces for Sale in Durham County, NC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Colonial Square Office/Medical Building
    Colonial Square Office/Medical Building

    4400 Ben Franklin Boulevard, Durham, NC 27704

    $3,499,000
    21,532 sqft 2.10 AC lot

    Multi-functional commercial building in Durham's Independence Park.

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    Two-Story Office and Medical Building
    Two-Story Office and Medical Building

    4400 Ben Franklin Boulevard, Durham, NC 27704

    $3,499,000
    21,532 sqft

    Flexible office and medical facility with elevator, ample storage, and a loading dock, including existing leased area.

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    Two-Story Office Building
    Two-Story Office Building

    3621 Lyckan Parkway, Durham, NC 27707

    Contact for pricing
    12,000 sqft

    Two-story, partial-shell office building with infrastructure in place for customized office or medical build-outs.

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    Renovated Mixed-Use Restaurant and Offices
    Renovated Mixed-Use Restaurant and Offices

    2022 Chapel Hill Rd., Durham, NC 27707

    $1,700,000

    A 2017 renovated mixed-use building with full-service restaurant space, a rooftop dining patio, and second-floor office use.

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    Durham Office Near Highway 85
    Durham Office Near Highway 85

    3219 Guess, Durham, NC 27705

    $750,000
    1,600 sqft

    Office property close to Highway 85, Duke, and RTP.

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    Medical Office & Wellness Center
    Medical Office & Wellness Center

    3017 Pickett Rd, Durham, NC 27705

    Contact for pricing
    25,317 sqft

    Medical office and wellness center in high-traffic Durham location.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Prime Development Opportunity in Greenville

    39 Airpark Ct, Greenville, SC 29607

    Contact for pricing

    1.27 acre interstate-visible land for ground lease or build-to-suit.

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    Commercial Land Parcel with Utilities
    Commercial Land Parcel with Utilities

    2585 Maple Lane, Pittsburgh, PA 15241

    $50,000/Mo

    Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

    View details
    Prime Lexington Outlot Opportunity
    Prime Lexington Outlot Opportunity

    3330 Partner Place, Lexington, KY 40503

    Contact for pricing

    Outlot for ground lease or build-to-suit in South Lexington.

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    Prime Commercial Lot For Rent
    Prime Commercial Lot For Rent

    Tift Avenue N, Tifton, GA 31794

    $7,500/Mo

    0.66 acre commercial lot with high visibility.

    View details

    Durham County, NC Medical Office Space Market Trends and Statistics

    Explore Medical Office Space leasing options in Durham County, NC with 6 listings featured on our commercial real estate exchange. The current inventory includes 8,605 square feet of properties with an estimated lease value of $61.13 SF/Yr.

    Estimated lease rates for Medical Office Space in Durham County, NC begin at $4.63 SF/Yr, with an average of $15.28 SF/Yr and extend to $20.50 SF/Yr.
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