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    Durham County, NC Medical Office Space for Lease

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    Charlotte, NC Raleigh, NC Greensboro, NC
    6 results
    Prime Medical Office Space Available
    $18 SF/Yr
    2,312 SF

    Prime Medical Office Space Available

    2609 N Duke Street, Durham, NC 27704

    Versatile medical/office space in Durham's thriving North Duke corridor.

    • Prime medical/office space in a highly sought‑after location on Durham's North Duke Street corridor.
    • Excellent visibility and easy access to major roads and highways.
    • Dedicated parking with ample spaces for clients and staff.
    • Versatile space ideal for medical, dental, or general office use.
    • Includes reception area, private offices, conference rooms, and ADA‑compliant restrooms.
    Updated: Dec 4, 2024
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    Roxboro Road Professional Office Space
    $20 SF/Yr
    2,408 SF

    Roxboro Road Professional Office Space

    4210 N. Roxboro Street, Suite 140, Durham, NC 27704

    Office space ideal for professional services and medical offices.

    • Prime location in a high‑visibility area with excellent traffic counts (26,250 VPD).
    • Close proximity to I‑85 and Duke Regional Hospital.
    • Ample parking with a great parking ratio of 5.5/1,000.
    • ±2,408 SF office space suitable for professional services and medical offices.
    • Single‑story, end‑bay office condo with windows on three sides.
    Updated: Jan 27
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    Medical Office Space Sublease
    Contact for pricing
    1,504 SF

    Medical Office Space Sublease

    Medical office space available for sublease.

    5015 Southpark Dr, Durham, NC 27713
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    South Durham Medical Office Space
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    South Durham Medical Office Space

    Medical office space in South Durham with ample parking.

    415 W NC Hwy. 54, Durham, NC 27215
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    Move-in Ready Office Suite
    $21 SF/Yr
    1,000 SF

    Move-in Ready Office Suite

    First-floor office suite in a high-demand Durham location.

    1804 Martin Luther King Jr Pkwy, Durham, NC 27707
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    Medical Office Space For Lease
    Contact for pricing

    Medical Office Space For Lease

    Second generation medical office space available for lease.

    4020 N Roxboro St, Durham, NC 27704
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    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 6 Active listings in Durham County, NC, we suggest exploring alternatives. Similar 4 Properties for Sales.

    Similar Spaces for Sale in Durham County, NC

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF
    Colonial Square Office/Medical Building

    Multi-functional commercial building in Durham's Independence Park.

    4400 Ben Franklin Boulevard, Durham, NC 27704

    View details
    Medical Office & Wellness Center
    Contact for pricing
    25,317 SF
    Medical Office & Wellness Center

    Medical office and wellness center in high-traffic Durham location.

    3017 Pickett Rd, Durham, NC 27705

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    Durham Office Near Highway 85
    $750,000
    1,600 SF
    Durham Office Near Highway 85

    Office property close to Highway 85, Duke, and RTP.

    3219 Guess, Durham, NC 27705

    View details
    Renovated Medical Office Condos
    Contact for pricing
    41,588 SF
    Renovated Medical Office Condos

    Newly renovated medical office condos for sale in Durham, NC.

    4020 N Roxboro St, Durham, NC 27704

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Development Opportunity in Greenville
    Contact for pricing

    Prime Development Opportunity in Greenville

    1.27 acre interstate-visible land for ground lease or build-to-suit.

    39 Airpark Ct, Greenville, SC 29607
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    Prime Lexington Outlot Opportunity
    Contact for pricing

    Prime Lexington Outlot Opportunity

    Outlot for ground lease or build-to-suit in South Lexington.

    3330 Partner Place, Lexington, KY 40503
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    Beaumont Centre Outparcel Opportunity
    Contact for pricing

    Beaumont Centre Outparcel Opportunity

    Outparcel opportunity in established shopping center for ground lease.

    3199 Beaumont Centre Circle, Lexington, KY 40513
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    Prime Commercial Lot For Rent
    $7,500/Mo

    Prime Commercial Lot For Rent

    0.66 acre commercial lot with high visibility.

    Tift Avenue N, Tifton, GA 31794
    View details

    Durham County, NC Medical Office Space Leasing Opportunities Market Analysis

    Explore Medical Office Space leasing options in Durham County, NC with 6 listings featured on our commercial real estate exchange. The current inventory includes 5,720 square feet of properties with an estimated lease value of $60 SF/Yr.

    Estimated lease rates for Medical Office Space in Durham County, NC begin at $18 SF/Yr, with an average of $20 SF/Yr and extend to $21 SF/Yr.
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