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3925 N Duke St, Unit 121 Durham, NC 27704

Sponsored
For Lease
$3,000 /Mo ($15 SF/Yr)

COMMERCIAL - Durham, NC

Type:Office
Property size:
2,400 SF
Lot size:
1.51 Acres
Days on Market:
2
Last Refresh:
Feb 19 at 10:06 pm

Property Features for 3925 N Duke St

General Information

Property type
Commercial Lease
Property subtype
Office
Standard status
Active
Zoning
GC
Rooms
Basement
APN
127501
Size
2,400 SF
Lot size
1.51 Acres

Utilities

Cooling system
Central Air

Building Details

Year built
1986
Building materials
Brick

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Listing Contact
Kelly Sauls

Encore Properties (919) 868-0008

Listing agent Kelly Sauls (919) 868-0008

Listing date Feb 18, 2026

MLS# 10147143

Copyright © 2026 Doorify MLS. All rights reserved. All information provided by the listing agent/broker is deemed reliable but is not guaranteed and should be independently verified.

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Property Insight Report

Overview

Versatile Office/Medical Space Available

This 2400 sq ft office/medical suite, located at 3925 N Duke St, Suite 121 in Durham, NC, will be available in March. The space is situated in a convenient and visible location, minutes from downtown and Duke Regional Hospital. Previously a dental practice and most recently a salon, the suite is designed for flexibility and can support various professional and service-based businesses. The layout includes five private offices arranged around an open main workspace, a spacious reception area, and a separate staff/filing room. The suite also features one bathroom and modern, low-maintenance LVP flooring throughout. The property, situated on a 1.51-acre lot, is zoned GC. This space is suitable for medical or dental practices, beauty and wellness studios, professional offices, or other service-oriented businesses seeking a central, accessible Durham location with built-in flexibility.
Property Profile Insight Report Location Intelligence

Current Use by Public Records

Dr. Ernest E. ... Dental Office Self-Perceptions, LLC Wellness Program Endivo Hair Gallery Spa & Massage Center CAPS4U Crisis Center New Life Provision ... Church

Suggested Use

Real Estate Agency Law Firm Restaurant Spa & Massage Center Dental Office Hair Salon Nail Salon Building Supply Auto Repair Shop Gym & Fitness Center

Zoning and permitted uses should be independently verified with local authorities.

Similar Places Nearby

Durham Animal Hospital

Location Insight

  • Map
  • Local Demand
City
Durham
County
Durham
State
North Carolina
Longitude
-78.904577
Latitude
36.054884

FAQs

What type of property is this?
Medical office - 2400 sq ft office/medical suite in prime Durham location.
Where is this medical office located?
The property is located at 3925 N Duke St, Unit 121 Durham, NC.
What is the lease rate?
The lease rate is $15 SF/Yr.
What are key features of this property?
This property features: - Prime Durham location, minutes from downtown and Duke Regional Hospital.; - Versatile 2400 sq ft space suitable for office, medical, or service-based businesses.; - Five private offices plus open central workspace.
More about this property
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