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    Durham County, NC Office Buildings for Sale

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    Charlotte, NC Hayesville, NC Fayetteville, NC
    10 results
    Colonial Square Office/Medical Building
    $3,499,000
    21,532 SF

    Colonial Square Office/Medical Building

    4400 Ben Franklin Boulevard, Durham, NC 27704

    Multi-functional commercial building in Durham's Independence Park.

    • Significant income generation from leased area: $227,739 in 2024.
    • Large, multi‑functional commercial building with 21,532 total square feet.
    • Located in a sought‑after office/medical park in northern Durham County.
    • Flexible space suitable for various professional uses (medical, office, education, law).
    • Features include an elevator, ample storage, and a loading dock.
    Updated: Aug 7, 2025
    View details
    Imperial Center Office Building For Sale
    Contact for pricing
    105,410 SF

    Imperial Center Office Building For Sale

    4819 Emperor Blvd., Durham, NC 27703

    Four-story office building in Imperial Center Business Park with modern amenities.

    • Highly visible building signage available from I‑40.
    • Located in the award‑winning Imperial Center Business Park, minutes from I‑40, I‑540, and RDU International Airport.
    • Gold LEED Facility.
    • Newly renovated lobby and outdoor seating.
    • Walkable to the Sheraton Imperial hotel's convention center, restaurants, market café, and bar.
    Updated: Jan 27
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    Class A Office Building, Durham
    Contact for pricing
    111,689 SF

    Class A Office Building, Durham

    Four-story Class A office building in Imperial Center Business Park.

    4309 Emperor Blvd., Durham, NC 27703
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    Imperial Center Office Building For Sale
    Contact for pricing
    81,145 SF

    Imperial Center Office Building For Sale

    Three-story office building in Imperial Center Business Park with walkable amenities.

    4307 Emperor Boulevard, Durham, NC 27703
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    Imperial Center Office Building For Sale
    Contact for pricing
    75,563 SF

    Imperial Center Office Building For Sale

    Three-story office building in Imperial Center Business Park.

    1101 Slater Road, Durham, NC 27703
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    Landmark Class-A Office Tower
    Contact for pricing
    264,598 SF

    Landmark Class-A Office Tower

    Iconic 11-story office building with prime location and amenities.

    4820 Emperor Boulevard, Durham, NC 27703
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    Class A Office Campus Redevelopment
    Contact for pricing
    151,376 SF

    Class A Office Campus Redevelopment

    Two-building Class A office campus with modern indoor/outdoor workspaces.

    2222 & 2224 NC 54, Durham, NC 27713
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    Versatile Income-Producing Asset in Durham
    $5,500,000
    34,433 SF

    Versatile Income-Producing Asset in Durham

    Multi-tenant building in a growing submarket with redevelopment potential.

    1020 South Miami Blvd, Durham, NC, USA, Durham, NC 27703
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    Turnkey Commercial Buildings in Durham
    Contact for pricing

    Turnkey Commercial Buildings in Durham

    Freestanding commercial buildings perfect for owner-user office or redevelopment.

    2117 Guess Rd, Durham, NC 27705
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    Southpoint Professional Center Office Space
    $2,995,000
    8,986 SF

    Southpoint Professional Center Office Space

    Office space in Durham, close to Chapel Hill and RTP.

    249 E Nc Hwy 54- Suite 100, Durham, NC 27713
    View details
    Based on your search, we've compiled 415 Potential Opportunities for your consideration. Besides 10 Active listings in Durham County, NC, we suggest exploring several alternatives: similar 401 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Buildable Lot in Growing Corridor
    $247,500
    0.19 Acres

    Buildable Lot in Growing Corridor

    Buildable lot in Durham with development potential.

    1902 Angier Avenue, Durham, NC 27703
    View details
    Buildable Lot in Growing Durham
    $247,500
    0.19 Acres

    Buildable Lot in Growing Durham

    Buildable lot in Durham with development potential and convenient location.

    1900 Angier Avenue, Durham, NC 27703
    View details
    Chapel Hill Land For Sale
    Contact for pricing
    1,819 SF

    Chapel Hill Land For Sale

    Corner lot available in Chapel Hill, North Carolina.

    307 N Columbia Street, Chapel Hill, NC 27516
    View details
    Cary Parkway Land For Sale
    $1,375,000
    2.29 Acres

    Cary Parkway Land For Sale

    Land available along SW Cary Parkway suitable for various commercial uses.

    1016 Kilarney Ridge Loop, Cary, NC 27511
    View details

    Explore Off-Market Properties in Durham County, NC

    Consider similar Off-Market properties in Durham County, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3608 University Dr

    3608 University Dr

    OFFICE BUILDING • 13,698 SF
    Value Estimation
    $2,955,000
    3608 University Dr, Durham, NC 27707-6260
    View details
    2222 Nc Hwy 54

    2222 Nc Hwy 54

    OFFICE BUILDING • 154,972 SF
    Value Estimation
    $9,385,000
    2222 Nc Hwy 54, Durham, NC 27713-5222
    View details
    1912 Nc Hwy 54

    1912 Nc Hwy 54

    OFFICE BUILDING • 8,876 SF
    Value Estimation
    $1,160,000
    1912 Nc Hwy 54, Durham, NC 27713-2235
    View details
    2513 Nc Hwy 54

    2513 Nc Hwy 54

    OFFICE BUILDING • 4,032 SF
    Value Estimation by Request
    2513 Nc Hwy 54, Durham, NC 27713-2697
    View details
    3211 Shannon Rd

    3211 Shannon Rd

    OFFICE BUILDING • 140,522 SF
    Value Estimation
    $22,900,000
    3211 Shannon Rd, Durham, NC 27707-6322
    View details
    2733 Campus Walk Ave

    2733 Campus Walk Ave

    OFFICE BUILDING • 5,376 SF
    Value Estimation
    $1,295,000
    2733 Campus Walk Ave, Durham, NC 27705
    View details
    4117 Roxboro St

    4117 Roxboro St

    OFFICE BUILDING • 51,910 SF
    Value Estimation by Request
    4117 Roxboro St, Durham, NC 27704-2121
    View details
    4101 Roxboro St

    4101 Roxboro St

    OFFICE BUILDING • 55,920 SF
    Value Estimation by Request
    4101 Roxboro St, Durham, NC 27704-2121
    View details
    1011 Lamond Ave

    1011 Lamond Ave

    PROFESSIONAL BUILDING • 2,145 SF
    Value Estimation
    $1,180,000
    1011 Lamond Ave, Durham, NC 27701-2020
    View details
    612 Gary St

    612 Gary St

    OFFICE BUILDING • 2,080 SF
    Value Estimation by Request
    612 Gary St, Durham, NC 27703-2202
    View details
    1622 Nc Hwy 54

    1622 Nc Hwy 54

    PROFESSIONAL BUILDING • 6,876 SF
    Value Estimation
    $965,000
    1622 Nc Hwy 54, Durham, NC 27713-2100
    View details
    4000 Sancar Way

    4000 Sancar Way

    OFFICE BUILDING • 77,675 SF
    Value Estimation
    $5,425,000
    4000 Sancar Way, Durham, NC 27709-1103
    View details
    6101 Quadrangle Dr

    6101 Quadrangle Dr

    PROFESSIONAL BUILDING • 31,542 SF
    Value Estimation
    $12,100,000
    6101 Quadrangle Dr, Chapel Hill, NC 27517-8622
    View details
    5606 Nc Hwy 55

    5606 Nc Hwy 55

    PROFESSIONAL BUILDING • 4,310 SF
    Value Estimation
    $980,000
    5606 Nc Hwy 55, Durham, NC 27713-4475
    View details

    Durham County, NC Office Buildings Investment Opportunities Market Analysis

    Explore 411 office buildings for sale in Durham County, NC, showcased through 10 active listings on our real estate platform. These investment opportunities span a total of 11,859,223 square feet of properties for sale, with an estimated market value of $381,829,000.

    Sale prices for office properties in Durham County, NC start at $115,000, averaging $2,121,272, and reaching up to $68,240,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office buildings for Sale Near Durham, NC

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