Medical Space

Durham, NC Medical Office Space for Lease

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Chapel Hill, NC Raleigh, NC Cary, NC
7 properties
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Private Office Suite Space
Updated: Jun 29
Private Office Suite Space

3201 Yorktown Avenue, Durham, NC 27713

$350/Mo
907 sqft · $4 SF/Yr
Built in 1988
Private office rooms with shared common area
24‑hour access
WiFi and utilities included
Convenient location near RTP, Downtown, and highways
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CG-Zoned Commercial Space
Updated: May 18
CG-Zoned Commercial Space

2810 Hillsborough Road, Durham, NC 27705

$18 SF/Yr
2,978 sqft · $4,467/Mo
$18/SF/yr lease rate plus TICAM for a 2,978 SF CG‑zoned commercial suite
2,810 Hillsborough Rd sits on a 0.24‑acre parcel on Hillsborough Road in Durham
Commercial General (CG) zoning supports a broad range of uses including retail, office, food & beverage, medical, and financial services
Located on a high‑traffic corridor connecting Downtown Durham to Duke University
Over 181,000 residents within a 5‑mile radius, with population growth projected above 6% through 2030
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Roxboro Road Professional Office Space
Roxboro Road Professional Office Space

4210 N. Roxboro Street, Suite 140, Durham, NC 27704

$20 SF/Yr
2,408 sqft · $4,113/Mo

Office space ideal for professional services and medical offices.

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Prime Medical Office Space Available
Prime Medical Office Space Available

2609 N Duke Street, Durham, NC 27704

$18 SF/Yr
2,312 sqft · $3,468/Mo

Versatile medical/office space in Durham's thriving North Duke corridor.

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South Durham Medical Office Space
South Durham Medical Office Space

415 W NC Hwy. 54, Durham, NC 27215

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Medical office space in South Durham with ample parking.

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Medical Office Space Sublease
Medical Office Space Sublease

5015 Southpark Dr, Durham, NC 27713

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1,504 sqft

Medical office space available for sublease.

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Medical Office Space For Lease
Medical Office Space For Lease

4020 N Roxboro St, Durham, NC 27704

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Second generation medical office space available for lease.

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Based on your search, we've compiled 21 Potential Opportunities for your consideration. Besides 7 Active listings in Durham, NC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 6 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Blue Ridge Road Office Space
Blue Ridge Road Office Space

3126 Blue Ridge Road, Raleigh, NC 27612

Contact for pricing
5,432 sqft

Medical or general office space for lease near UNC Rex.

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Medical Outpatient and R&D Building
Medical Outpatient and R&D Building

4225 Macon Pond Road, Raleigh, NC 27607

Contact for pricing
62,246 sqft

State-of-the-art Class A medical and R&D space available.

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Retail, Medical, or Office Space
Retail, Medical, or Office Space

1200 Gathering Park Cir, Cary, NC 27519

$28 SF/Yr

First floor end unit suitable for retail, medical, or office.

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Class A Medical Office Building
Class A Medical Office Building

7560 Carpenter Fire Station Rd, Cary, NC 27519

$30 SF/Yr
36,000 sqft · $90,000/Mo

Three-story medical office building with variety of medical tenants.

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Similar Spaces for Sale in Durham, NC

Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

Colonial Square Office/Medical Building
Colonial Square Office/Medical Building

4400 Ben Franklin Boulevard, Durham, NC 27704

$3,499,000
21,532 sqft · 2.10 AC lot

Multi-functional commercial building in Durham's Independence Park.

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Renovated Mixed-Use Restaurant and Offices
Renovated Mixed-Use Restaurant and Offices

2022 Chapel Hill Rd., Durham, NC 27707

$1,700,000

A 2017 renovated mixed-use building with full-service restaurant space, a rooftop dining patio, and second-floor office use.

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Two-Story Office and Medical Building
Two-Story Office and Medical Building

4400 Ben Franklin Boulevard, Durham, NC 27704

$3,499,000
21,532 sqft

Flexible office and medical facility with elevator, ample storage, and a loading dock, including existing leased area.

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Two-Story Office Building
Two-Story Office Building

3621 Lyckan Parkway, Durham, NC 27707

Contact for pricing
12,000 sqft

Two-story, partial-shell office building with infrastructure in place for customized office or medical build-outs.

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Durham Office Near Highway 85
Durham Office Near Highway 85

3219 Guess, Durham, NC 27705

$750,000
1,600 sqft

Office property close to Highway 85, Duke, and RTP.

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Medical Office & Wellness Center
Medical Office & Wellness Center

3017 Pickett Rd, Durham, NC 27705

Contact for pricing
25,317 sqft

Medical office and wellness center in high-traffic Durham location.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Development Opportunity in Greenville
Prime Development Opportunity in Greenville

39 Airpark Ct, Greenville, SC 29607

Contact for pricing

1.27 acre interstate-visible land for ground lease or build-to-suit.

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Commercial Land Parcel with Utilities
Commercial Land Parcel with Utilities

2585 Maple Lane, Pittsburgh, PA 15241

$50,000 SF/Yr

Level, fully serviced commercial parcel with approvals in place and signage permitted up to 20 sq ft.

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Prime Lexington Outlot Opportunity
Prime Lexington Outlot Opportunity

3330 Partner Place, Lexington, KY 40503

Contact for pricing

Outlot for ground lease or build-to-suit in South Lexington.

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Beaumont Centre Outparcel Opportunity
Beaumont Centre Outparcel Opportunity

3199 Beaumont Centre Circle, Lexington, KY 40513

Contact for pricing

Outparcel opportunity in established shopping center for ground lease.

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Durham, NC Medical Office Space Market Trends and Statistics

Explore Medical Office Space leasing options in Durham, NC with 7 listings featured on our commercial real estate exchange. The current inventory includes 8,605 square feet of properties with an estimated lease value of $61 SF/Yr.

Estimated lease rates for Medical Office Space in Durham, NC begin at $4 SF/Yr, with an average of $15 SF/Yr and extend to $20 SF/Yr.
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