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    Durham County, NC Mixed-use Properties for Lease

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    Found 6 mixed-use properties for lease in Durham County, NC, averaging $25/sq ft/yr. Use lease type data to compare options faster.
    Erwin Road Mixed-Use Retail Space
    Updated: Sep 25, 2025
    Erwin Road Mixed-Use Retail Space

    2812 & 2816 Erwin Rd, Durham, NC 27705

    $25 SF/Yr
    2,550 sqft
    Walking distance to Duke University Hospital, Duke University, Durham VA Hospital, and Lenox Baker Children’s Hospital
    Class A mixed‑use development with luxury apartments, offices, and retail
    Ample surface and structured parking
    Convenient to US 15‑501 and NC 147/Durham Freeway
    Property adjoins a 141‑key AC Hotel by Marriott
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    One City Center Mixed-Use High-Rise
    Updated: Aug 23
    One City Center Mixed-Use High-Rise

    110 Corcoran St., Durham, NC 27701

    Contact for pricing
    27‑story mixed‑use high‑rise
    One City Center property name
    Located at 110 Corcoran St., Durham, NC 27701
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    Mixed-Use Development
    Mixed-Use Development

    5720 - 5850 Fayetteville Rd., Durham, NC 27713

    Contact for pricing

    Combines retail, office, and residential components within one development.

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    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Mixed-Use Development Opportunity in Durham
    Mixed-Use Development Opportunity in Durham

    3214 Hillsborough Road, Durham, NC 27705

    Contact for pricing

    Mixed-use development with retail, restaurants, and residential dwellings.

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    Downtown Durham Mixed-Use Asset
    Downtown Durham Mixed-Use Asset

    601 West Main Street, Durham, NC 27701

    Contact for pricing

    Mixed-use property in the heart of Downtown Durham.

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    Mixed-Use Redevelopment Opportunity
    Mixed-Use Redevelopment Opportunity

    University Dr & Shannon Rd, Durham, NC 27707, USA, Durham, NC 27707

    Contact for pricing

    Mixed-use redevelopment with main street setting.

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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 6 Active listings in Durham County, NC, we suggest exploring alternatives. Similar 6 Properties for Sales.

    Similar Spaces for Sale in Durham County, NC

    Consider Similar Space for Sale. We found 6 Spaces matching your search parameters.

    Commercial Flex Space
    Commercial Flex Space

    3421 Angier Ave, Durham, NC 27703

    Contact for pricing
    2,296 sqft 0.80 AC lot

    General Commercial zoning accompanies a versatile building configuration on an established commercial corridor.

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    NNN Property with Retail Space
    NNN Property with Retail Space

    1105 W Main Street Ste 100, Durham, NC 27701

    Contact for pricing
    5,985 sqft

    A 2019 condominium component with expansive glazing, city views, and solar-equipped parking canopies serving common areas.

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    Downtown Durham Mixed-Use Property
    Downtown Durham Mixed-Use Property

    114 E Main St, Durham, NC 27701

    Contact for pricing
    2,386 sqft

    Historic building with modern upgrades, suitable for multiple uses.

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    Retail and Office Development Site
    Retail and Office Development Site

    5802 & 5904 S Miami Blvd |, Durham, NC 27560

    Contact for pricing
    33 sqft

    Approved site for 33,000 SF retail and office development.

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    Mixed-Use Building with Large Lot
    Mixed-Use Building with Large Lot

    1109 E Main St, Durham, NC 27701

    Contact for pricing
    0.87 AC lot

    Multi-use commercial property with substantial interior space and an outdoor lot near downtown Durham’s retail, dining, and entertainment district.

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    Durham Mixed-Use Asset Near Duke
    Durham Mixed-Use Asset Near Duke

    2816 Erwin Rd, Durham, NC 27705

    Contact for pricing
    105,055 sqft

    Mixed-use asset near Duke University with multifamily, retail, office.

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    Durham County, NC Mixed-use properties Market Trends and Statistics

    Explore Mixed-use properties leasing options in Durham County, NC with 6 listings featured on our commercial real estate exchange. The current inventory includes 2,550 square feet of properties with an estimated lease value of $25.

    Estimated lease rates for Mixed-use properties in Durham County, NC average $25 SF/Yr.
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