Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Mixed-Use
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Durham County, NC Mixed-use Properties for Sale

    List
    Map
    Charlotte, NC Hayesville, NC Fayetteville, NC
    6 results
    Durham Automotive/Retail Opportunity
    $750,000
    2,640 SF

    Durham Automotive/Retail Opportunity

    901 E Trinity Ave, Durham, NC 27704

    Vacant property in Durham with high visibility and strong potential.

    • Prime location on a high‑traffic corridor ensures excellent visibility and strong demand.
    • Tenant ready to sign a Double Net (NN) lease at $5,500/month for immediate cash flow.
    • Suitable for both investors and owner‑users, offering maximum flexibility.
    • Body‑shop‑ready facility, a scarce and desirable asset in Durham.
    • Strong potential cap rate with minimal landlord responsibilities under the NN lease.
    Updated: Nov 17, 2025
    View details
    Downtown Durham Multifamily Development Opportunity
    Contact for pricing
    8,721 SF

    Downtown Durham Multifamily Development Opportunity

    6 Grace Ln, Durham, NC 27701

    Entitled mixed-use site with 201 residential units and commercial space.

    • Rare, fully entitled multifamily development opportunity.
    • Site‑plan approved for a mixed‑use project comprising 201 residential units and 8,721 square feet of ground‑floor commercial space.
    • ±1.65‑acre site.
    • Located in the heart of Downtown Durham with immediate access to employment, dining, entertainment, and cultural amenities.
    • Located within a federally designated Opportunity Zone.
    Updated: Feb 9
    View details
    Downtown Durham Mixed-Use Property
    $1,400,000
    4,500 SF

    Downtown Durham Mixed-Use Property

    Mixed-use property in Downtown Durham with office and residential spaces.

    116 East Main Street, Durham, NC 27701
    View details
    Multi-Purpose Building on 2.24 Acres
    $799,900
    1.27 Acres

    Multi-Purpose Building on 2.24 Acres

    Well-maintained multi-purpose building on 2.24 acres with lease in place.

    315 Southerland St, Durham, NC 27703
    View details
    Retail and Office Development Site
    Contact for pricing

    Retail and Office Development Site

    Approved site for 33,000 SF retail and office development.

    5802 & 5904 S Miami Blvd |, Durham, NC 27560
    View details
    Downtown Durham Mixed-Use Property
    $1,400,000
    4,500 SF

    Downtown Durham Mixed-Use Property

    Mixed-use property in Downtown Durham with office and residential spaces.

    116 E Main, Durham, NC 27701
    View details
    Based on your search, we've compiled 132 Potential Opportunities for your consideration. Besides 6 Active listings in Durham County, NC, we suggest exploring several alternatives: similar 122 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Highway 751 Land Opportunity
    $2,500,000

    Highway 751 Land Opportunity

    Large 3.7+ acre property near I-40 and Southpoint.

    8202 N.C. Highway 751, Durham, NC 27713
    View details
    Residential Land Assemblage in Durham
    $3,400,000
    61.00 Acres

    Residential Land Assemblage in Durham

    61 acres of residential land in Northeast Durham, North Carolina.

    1720 Glenn School Road, Durham, NC 27704
    View details
    Prime Commercial Site in Durham
    $2,755,000
    5.79 Acres

    Prime Commercial Site in Durham

    Highly visible commercial land near Brier Creek and Research Triangle Park.

    2214 T W Alexander Drive, Durham, NC 27703
    View details
    Prime Commercial Site in Durham
    $2,755,000
    5.79 Acres

    Prime Commercial Site in Durham

    Highly visible commercial land near Brier Creek and Research Triangle Park.

    2214 T W Alexander Drive, Durham, NC 27703
    View details

    Explore Off-Market Properties in Durham County, NC

    Consider similar Off-Market properties in Durham County, NC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    1827 Alston Ave

    1827 Alston Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,686 SF
    Value Estimation by Request
    1827 Alston Ave, Durham, NC 27707-4305
    View details
    2623 Durham Chapel Hl Blvd

    2623 Durham Chapel Hl Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,000 SF
    Value Estimation
    $1,075,000
    2623 Durham Chapel Hl Blvd, Durham, NC 27707-2860
    View details
    202 Corcoran St

    202 Corcoran St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 132,302 SF
    Value Estimation
    $27,500,000
    202 Corcoran St, Durham, NC 27701-3392
    View details
    114 Nc Hwy 54

    114 Nc Hwy 54

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,098 SF
    Value Estimation
    $700,000
    114 Nc Hwy 54, Durham, NC 27713-2136
    View details
    2731 Durham Chapel Hl Blvd

    2731 Durham Chapel Hl Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,541 SF
    Value Estimation by Request
    2731 Durham Chapel Hl Blvd, Durham, NC 27707-2869
    View details
    1008 Chapel Hl St

    1008 Chapel Hl St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,807 SF
    Value Estimation
    $700,000
    1008 Chapel Hl St, Durham, NC 27701-3026
    View details
    2919 Fayetteville St

    2919 Fayetteville St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,841 SF
    Value Estimation
    $815,000
    2919 Fayetteville St, Durham, NC 27707-4175
    View details
    3009 Fayetteville St

    3009 Fayetteville St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,768 SF
    Value Estimation by Request
    3009 Fayetteville St, Durham, NC 27707-4135
    View details
    3311 Guess Rd

    3311 Guess Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,376 SF
    Value Estimation
    $1,260,000
    3311 Guess Rd, Durham, NC 27705-2105
    View details
    3222 Guess Rd

    3222 Guess Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 9,975 SF
    Value Estimation
    $1,970,000
    3222 Guess Rd, Durham, NC 27705-2647
    View details
    3421 Angier Ave

    3421 Angier Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,296 SF
    Value Estimation by Request
    3421 Angier Ave, Durham, NC 27703-5107
    View details
    1101 Miami Blvd

    1101 Miami Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,087 SF
    Value Estimation
    $1,470,000
    1101 Miami Blvd, Durham, NC 27703-2231
    View details
    3219 Old Chapel Hl Rd

    3219 Old Chapel Hl Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 7,954 SF
    Value Estimation
    $1,330,000
    3219 Old Chapel Hl Rd, Durham, NC 27707-6232
    View details
    1612 Geer St

    1612 Geer St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,900 SF
    Value Estimation by Request
    1612 Geer St, Durham, NC 27704-4720
    View details
    3341 Roxboro St

    3341 Roxboro St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,900 SF
    Value Estimation by Request
    3341 Roxboro St, Durham, NC 27704-3255
    View details
    5337 Roxboro Rd

    5337 Roxboro Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 15,221 SF
    Value Estimation
    $2,010,000
    5337 Roxboro Rd, Durham, NC 27712-2227
    View details
    4321 Medical Park Dr

    4321 Medical Park Dr

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 79,440 SF
    Value Estimation
    $10,645,000
    4321 Medical Park Dr, Durham, NC 27704-2199
    View details
    806 Main St

    806 Main St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 14,763 SF
    Value Estimation
    $1,920,000
    806 Main St, Durham, NC 27701-2023
    View details

    Durham County, NC Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 128 mixed-use properties for sale in Durham County, NC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 2,816,154 square feet of properties for sale, with an estimated market value of $77,350,000.

    Sale prices for multi use buildings in Durham County, NC start at $130,000, averaging $1,089,436, and reaching up to $13,620,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Mixed-use properties by market

    Browse Mixed-use properties for Sale Near Durham, NC

    Popular Categories

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!