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Lee County, FL Live-work Space for Sale

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Prime Sanibel Commercial Landmark
$2,895,000
0.49 Acres

Prime Sanibel Commercial Landmark

1446 & 1444 Periwinkle Way, Sanibel, FL 33957

Versatile property on Periwinkle Way with retail, residential, and income potential.

  • Prime Periwinkle Way frontage with 150 feet in a high‑traffic commercial corridor.
  • Versatile property featuring a retail building (2,358 sq ft), a residence (2,390 sq ft, 4 bed/2 bath), and a workshop with apartment.
  • Significant income potential through rental of the apartment and/or commercial space.
  • Flexible usage options: retail, office, wellness center, or mixed commercial/residential.
  • Established landmark site with a history of success as the Island Trading Post.
Updated: Aug 22, 2025
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Live-Work Space with Garage
$649,000

Live-Work Space with Garage

18950 S Tamiami Trl 100, Fort Myers, FL 33908

Second-floor live-work space featuring a garage with lifts.

  • Garage with 2 lifts and epoxy floors
  • 14'x16' garage door for easy access
  • Office/bedroom provides flexible space
  • Walk‑in closet offers ample storage
  • Second floor with kitchenette
Updated: Apr 15
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Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 2 Active listings in Lee County, FL, we suggest exploring several alternatives: plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cape Coral Development Opportunity
$10,000,000
8,300 SF

Cape Coral Development Opportunity

Entitled land parcel with approved mixed-use development plans.

430 SW 47th Terrace, Cape Coral, FL 33914
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Historic Matlacha Bay Frontage Property
$574,000

Historic Matlacha Bay Frontage Property

Commercial land in Matlacha's Historic District with bay frontage.

4195 Pine Island Road, Cape Coral, FL 33991
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Port Charlotte Vacant Land Opportunity
$427,000
7.30 Acres

Port Charlotte Vacant Land Opportunity

7.3 acres of agricultural land near I-75 and US-41.

3400 Rowland Drive, Port Charlotte, FL 33980
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Lakewood Ranch Development Opportunity
$1,350,000

Lakewood Ranch Development Opportunity

1.2-acre mixed-use site in high-demand Lakewood Ranch Business Park.

10305 Technology Terrace, Bradenton, FL 34211
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Lee County, FL Live-Work Space Investment Opportunities Market Analysis

Explore 2 live-work space for sale in Lee County, FL on our real estate platform. These investment opportunities span a total of 21,423 square feet of properties for sale, with an estimated market value of $2,895,000.

Sale prices for live-work properties in Lee County, FL start at $2,895,000, averaging $2,895,000, and reaching up to $2,895,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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