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    South Carolina Healthcare Properties for Lease

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    Columbia, SC Greenville, SC Charleston, SC
    17 results
    Lady's Island Versatile Office Space
    $3,600/Mo

    Lady's Island Versatile Office Space

    27 Kemmerlin Lane, Beaufort, SC 29907

    Well-conditioned office space ideal for medical, wellness, or traditional office.

    • Versatile 1,500 SF office space suitable for medical, wellness, salon, or traditional office use.
    • 7 treatment rooms with plumbing stubbed and capped.
    • Located in Kemmerlin Business Park with noteworthy businesses and organizations.
    • Newly renovated lobby, two ADA restrooms, and kitchenette.
    • Front and rear covered patios and ~15 shared parking spaces.
    Updated: Feb 24
    View details
    Retail Center Renovation in Little River
    $1,913/Mo
    1,148 SF

    Retail Center Renovation in Little River

    4390 Spa Dr., Little River, SC 29566

    Retail and office spaces available in renovated Little River center.

    • Comprehensive renovation planned for completion in 2027, modernizing the property into a coastal‑inspired retail destination.
    • Flexible demising options allow for tenant spaces ranging from 1,100 SF to over 4,000 SF, accommodating diverse business needs.
    • Designed for a variety of uses including retail, medical, wellness, office, and food‑and‑beverage, broadening potential tenant base.
    • Modern coastal architectural design with enhanced storefront visibility, covered walkways, and a central focal point to attract customers.
    • Approximately 27,000 SF of space across multiple connected structures, including a main building with a second‑floor opportunity.
    Updated: Jan 21
    View details
    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF

    Premier Medical Office Space Available

    Class A medical office space in Spartanburg's prime location.

    1650 Skylyn Drive, Spartanburg, SC 29307
    View details
    New Retail/Office/Medical Space Available
    $35 SF/Yr
    8,450 SF

    New Retail/Office/Medical Space Available

    New retail, office, or medical spaces available in NE Columbia.

    565 Spears Creek Church Road, Elgin, SC 29045
    View details
    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr
    3,970 SF

    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    Bluffton, SC 29909
    View details
    Greer Retail/Office/Medical Space For Rent
    $14 SF/Yr
    2,100 SF

    Greer Retail/Office/Medical Space For Rent

    Flexible 2,100 SF space ideal for retail, office, or medical.

    1317 West Poinsett Street, Greer, SC
    View details
    Turnkey Healthcare Suite Available
    Contact for pricing

    Turnkey Healthcare Suite Available

    Ready-to-occupy medical suite with excellent visibility and accessibility.

    2709 Pelham Road, Greenville, SC 29615
    View details
    Renovated Shopping Center in Forest Acres
    Contact for pricing
    15,630 SF

    Renovated Shopping Center in Forest Acres

    Premier shopping center with upscale tenants in a desirable location.

    2710 Gervais Street, Columbia, SC 29204
    View details
    Renovated Office Suite in Mt. Pleasant
    Contact for pricing

    Renovated Office Suite in Mt. Pleasant

    Executive office suite available for sublease, renovated in 2024.

    1004 Anna Knapp Boulevard, Suite 3, Mount Pleasant, SC 29464
    View details
    Medical Space Available For Lease
    $19 SF/Yr
    2,500 SF

    Medical Space Available For Lease

    2500 SF medical space for lease in North Charleston.

    9263 Medical Plaza Drive, North Charleston, SC 29406
    View details
    Medical Office Space For Rent
    $28 SF/Yr
    3,649 SF

    Medical Office Space For Rent

    New construction medical office space with connection to hospital.

    986 Wellness Way, Fort Mill, SC
    View details
    Pleasantburg Drive Office Building
    $15 SF/Yr
    1,800 SF

    Pleasantburg Drive Office Building

    1,800 SF office building for lease on 0.48 acres.

    1934 N Pleasantburg Dr, Greenville, SC
    View details
    Retail Space in Surfside Beach
    Contact for pricing

    Retail Space in Surfside Beach

    Multi-tenant building for lease in the heart of Surfside Beach.

    Surfside Beach, SC 29575
    View details
    Retail and Office Space Available
    $30 SF/Yr
    1,816 SF

    Retail and Office Space Available

    Retail and medical office spaces for lease in Rock Hill.

    2460 India Hook Rd, Rock Hill, SC
    View details
    Medical Office Space For Rent
    Contact for pricing

    Medical Office Space For Rent

    Professional second-floor medical office space in Columbia, SC.

    710 Rabon Rd, Columbia, SC 29203
    View details
    New Retail/Office/Medical Space
    Contact for pricing

    New Retail/Office/Medical Space

    Newly constructed space on rapidly growing Spears Creek Church Road.

    565 Spears Creek Church Rd, Elgin, SC 29045
    View details
    Mount Pleasant Commercial Space Available
    Contact for pricing

    Mount Pleasant Commercial Space Available

    Commercial spaces available for office, medical, retail, and restaurants.

    3236 N Hwy 17, Mount Pleasant, SC 29466
    View details
    Based on your search, we've compiled 60 Potential Opportunities for your consideration. Besides 17 Active listings in South Carolina, we suggest exploring alternatives. Similar 43 Properties for Sales.

    Explore Similar Spaces for Sale in South Carolina

    Consider Similar Space for Sale. We found 43 Spaces matching your search parameters.

    Freestanding Commercial Site in Aiken
    $850,000
    9,012 SF

    Freestanding Commercial Site in Aiken

    Well-located commercial property with redevelopment potential in Aiken, SC.

    1110 Richland Avenue E, Aiken, SC 29801
    View details
    Belvedere Office/Activities Center For Sale
    $995,000
    6,889 SF

    Belvedere Office/Activities Center For Sale

    Single-story office building on 2.5 acres, suitable for various uses.

    725 Edgefield Road, Belvedere, SC 29841
    View details
    Charming Updated Office in Simpsonville
    Contact for pricing
    0.37 Acres

    Charming Updated Office in Simpsonville

    Prime location in Historic Downtown Simpsonville with rustic charm.

    312 S Main Street, Simpsonville, SC 29681
    View details
    Versatile Commercial Space in Gray Court
    $157,500
    0.10 Acres

    Versatile Commercial Space in Gray Court

    1000 sq ft commercial space suitable for various businesses.

    419 W Main Street, Gray Court, SC 29645
    View details
    Fountain Center Commercial Units
    $99,900

    Fountain Center Commercial Units

    Two adjacent commercial units in Fountain Center, Hilton Head Island.

    55 New Orleans Road, Hilton Head Island, SC 29928
    View details
    Murrells Inlet Senior Housing Opportunity
    $9,000,000
    34,479 SF

    Murrells Inlet Senior Housing Opportunity

    39-unit senior independent living community in Murrells Inlet, SC.

    11949 Grandhaven Dr., Murrells Inlet, SC 29576
    View details
    Turnkey Assisted Living Facility
    $1,400,000
    8,692 SF

    Turnkey Assisted Living Facility

    Fully occupied assisted living facility with 33 beds in Sumter.

    23 Kendrick Street, Sumter, SC 29150
    View details

    South Carolina Healthcare properties Leasing Opportunities Market Analysis

    Explore Healthcare properties leasing options in South Carolina with 17 listings featured on our commercial real estate exchange. The current inventory includes 8,508,836,160 square feet of properties with an estimated lease value of $279 SF/Yr.

    Estimated lease rates for Healthcare properties in South Carolina begin at $2 SF/Yr, with an average of $18 SF/Yr and extend to $30 SF/Yr.
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