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    South Carolina Healthcare Properties for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    16 listings
    Historic Downtown Simpsonville Office Space
    $5,084/Mo
    Historic Downtown Simpsonville Office Space

    312 S Main Street, Simpsonville, SC 29681

    Charming office space in historic downtown Simpsonville with ample parking.
    • Prime location in Historic Downtown Simpsonville with excellent visibility.
    • Elegantly finished reception area.
    • Five potential offices, including one suitable for a conference room.
    • Full kitchen and full bathroom.
    • Ample parking with approximately 12‑14 spaces.
    Updated: Feb 6
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    Office or Salon Space Available
    $1,300/Mo
    800 SF
    Office or Salon Space Available

    9898 Merry Ln., Murrells Inlet, SC 29576

    Rental space suitable for office or beauty salon in Murrells Inlet.
    • Space for rent.
    • Suitable for office rental.
    • Suitable for beauty salon.
    Updated: Feb 2
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    Premier Medical Office Space Available
    $20 SF/Yr
    7,039 SF
    Premier Medical Office Space Available

    Class A medical office space in Spartanburg's prime location.

    1650 Skylyn Drive, Spartanburg, SC 29307

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    New Retail/Office/Medical Space Available
    $35 SF/Yr
    8,450 SF
    New Retail/Office/Medical Space Available

    New retail, office, or medical spaces available in NE Columbia.

    565 Spears Creek Church Road, Elgin, SC 29045

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    Greer Retail/Office/Medical Space For Rent
    $14 SF/Yr
    2,100 SF
    Greer Retail/Office/Medical Space For Rent

    Flexible 2,100 SF space ideal for retail, office, or medical.

    1317 West Poinsett Street, Greer, SC

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    Highway 170 Retail/Office/Medical Space
    $36 SF/Yr
    3,970 SF
    Highway 170 Retail/Office/Medical Space

    Retail, office, or medical space for sale on Highway 170.

    Bluffton, SC 29909

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    Downtown Fort Mill Office Space
    $8 SF/Yr
    Downtown Fort Mill Office Space

    Private rooms available within established wellness center in Fort Mill.

    227 Main St, Fort Mill, SC 29715

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    Turnkey Healthcare Suite Available
    Contact for pricing
    Turnkey Healthcare Suite Available

    Ready-to-occupy medical suite with excellent visibility and accessibility.

    2709 Pelham Road, Greenville, SC 29615

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    Renovated Shopping Center in Forest Acres
    Contact for pricing
    15,630 SF
    Renovated Shopping Center in Forest Acres

    Premier shopping center with upscale tenants in a desirable location.

    2710 Gervais Street, Columbia, SC 29204

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    Renovated Office Suite in Mt. Pleasant
    Contact for pricing
    Renovated Office Suite in Mt. Pleasant

    Executive office suite available for sublease, renovated in 2024.

    1004 Anna Knapp Boulevard, Suite 3, Mount Pleasant, SC 29464

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    Medical Office Suite
    Contact for pricing
    1,880 SF
    Medical Office Suite

    Move-in ready OB-GYN medical space with strong visibility, signage, and ample parking for healthcare practices.

    3210 Landmark Drive, North Charleston, SC 29418

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    Pleasantburg Drive Office Building
    $15 SF/Yr
    1,800 SF
    Pleasantburg Drive Office Building

    1,800 SF office building for lease on 0.48 acres.

    1934 N Pleasantburg Dr, Greenville, SC

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    Retail Space in Surfside Beach
    Contact for pricing
    Retail Space in Surfside Beach

    Multi-tenant building for lease in the heart of Surfside Beach.

    Surfside Beach, SC 29575

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    Retail and Office Space Available
    $30 SF/Yr
    1,816 SF
    Retail and Office Space Available

    Retail and medical office spaces for lease in Rock Hill.

    2460 India Hook Rd, Rock Hill, SC

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    Medical Office Space For Rent
    $28 SF/Yr
    Medical Office Space For Rent

    Professional second-floor medical office space in Columbia, SC.

    710 Rabon Rd, Columbia, SC 29203

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    Mount Pleasant Commercial Space Available
    $40 SF/Yr
    Mount Pleasant Commercial Space Available

    Commercial spaces available for office, medical, retail, and restaurants.

    3236 N Hwy 17, Mount Pleasant, SC 29466

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    Based on your search, we've compiled 57 Potential Opportunities for your consideration. Besides 16 Active listings in South Carolina, we suggest exploring alternatives. Similar 41 Properties for Sales.

    Similar Spaces for Sale in South Carolina

    Consider Similar Space for Sale. We found 41 Spaces matching your search parameters.

    Medical Office Building with Exam Rooms
    $1,899,000
    3,988 SF
    Medical Office Building with Exam Rooms

    Brand-new medical office with 9 exam rooms, dedicated HVAC, and ample parking for patient-centered care.

    116 Professional Park Dr., Conway, SC 29526

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    Freestanding Commercial Site in Aiken
    $850,000
    9,012 SF
    Freestanding Commercial Site in Aiken

    Well-located commercial property with redevelopment potential in Aiken, SC.

    1110 Richland Avenue E, Aiken, SC 29801

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    Remodeled Medical Office Building
    $300,000
    2,165 SF
    Remodeled Medical Office Building

    Turnkey, fully rebuilt office suite with treatment-room style spaces, new HVAC, and updated plumbing and electrical.

    910 W Evans st, Florence, SC 29501

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    Renovated Commercial Building in Columbia
    $250,000
    1,138 SF
    Renovated Commercial Building in Columbia

    Multi-tenant property suitable for retail, medical, or aviation businesses.

    3201 Broad River Road, Columbia, SC 29210

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    Single-Story Office and Activity Center
    $995,000
    6,889 SF
    Single-Story Office and Activity Center

    Single-story office and activities building on 2.5 acres with multiple outbuildings and dedicated restroom facilities.

    725 Edgefield Road, Belvedere, SC 29841

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    Versatile Greenville Property with Parking
    $1,395,000
    4,000 SF
    Versatile Greenville Property with Parking

    Multipurpose property in Greenville with residential, office, and rental potential.

    906 Augusta Street, Greenville, SC 29605

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    Former Assisted Living Facility
    $1,850,000
    23,175 SF
    Former Assisted Living Facility

    Value-add investment opportunity with flexible reuse potential in Sumter, SC.

    1267 N Main Street, Sumter, SC 29153

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    Former Nursing Home on 5 Acres
    $150,000
    3,316 SF
    Former Nursing Home on 5 Acres

    Versatile property with flexible zoning on 5 picturesque acres.

    182 Roberts Street W, Salley, SC 29137

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    South Carolina Healthcare properties Leasing Opportunities Market Analysis

    Explore Healthcare properties leasing options in South Carolina with 16 listings featured on our commercial real estate exchange. The current inventory includes 26,100 square feet of properties with an estimated lease value of $178 SF/Yr.

    Estimated lease rates for Healthcare properties in South Carolina begin at $8 SF/Yr, with an average of $22 SF/Yr and extend to $36 SF/Yr.
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