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    Greenville County, SC Commercial Real Estate for Sale

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    Columbia, SC Greenville, SC Aiken, SC
    429 results
    Greenville Commercial Building For Sale
    $369,900
    0.34 Acres

    Greenville Commercial Building For Sale

    1 Elizabeth Drive, Greenville, SC 29615

    Commercial building with parking in high-traffic Greenville location.

    • Desirable location off Wade Hampton Boulevard in a high traffic area.
    • Zoned NC suitable for a variety of business and professional uses.
    • Approximately 1,600 SF one‑level brick building.
    • Total of 9 parking spaces.
    • Handicap access at rear of building.
    Updated: Apr 17
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    Charming Mountain Store Opportunity
    $650,000
    1.00 Acre

    Charming Mountain Store Opportunity

    4000 Geer Highway, Cleveland, SC 29635

    Turnkey cafe and general store in scenic Cleveland, SC.

    • Turnkey, fully operational café and general store.
    • High visibility location on a popular tourist route to Caesars Head and Table Rock.
    • Established business with a loyal customer base.
    • Full‑service kitchen and indoor seating.
    • Rustic, welcoming atmosphere capturing the spirit of the Blue Ridge Mountains.
    Updated: Apr 3
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    High-Visibility Highway Commercial Opportunity
    $350,000
    0.84 Acres

    High-Visibility Highway Commercial Opportunity

    Former auto repair shop on a high-traffic highway.

    2606 Geer Highway, Marietta, SC 29661
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    Commercial Property in Greenville, SC
    $390,000
    0.28 Acres

    Commercial Property in Greenville, SC

    Commercial property for sale in Greenville, South Carolina.

    1601 Rutherford Road, Greenville, SC 29609
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    High-Traffic Retail/Flex Greer, SC
    $1,600,000
    0.63 Acres

    High-Traffic Retail/Flex Greer, SC

    Adaptable commercial building with income potential in high-traffic location.

    14629 E Wade Hampton Boulevard, Greer, SC 29651
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    Downtown Fountain Inn Commercial Space
    $1,500,000
    0.59 Acres

    Downtown Fountain Inn Commercial Space

    Prime location with potential for various business uses.

    203 S Weston Street, Fountain Inn, SC 29644
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    Greenville Flex Industrial/Commercial Property
    $999,000
    0.69 Acres

    Greenville Flex Industrial/Commercial Property

    8,550 SF flex building on 0.69 acres near Donaldson Center.

    7 Akron Drive, Greenville, SC 29605
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    Established Preschool Property For Sale
    $750,000
    1.62 Acres

    Established Preschool Property For Sale

    Turnkey preschool property with fixtures and playground equipment included.

    615 Fairview Street, Fountain Inn, SC 29644
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    Professional Office Space in Simpsonville
    $425,000
    0.49 Acres

    Professional Office Space in Simpsonville

    Adaptable office space near downtown Simpsonville and Fairview Road.

    107 Hillcrest Avenue, Simpsonville, SC 29681
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    Versatile Commercial Property, Cleveland, SC
    $650,000
    1.89 Acres

    Versatile Commercial Property, Cleveland, SC

    Two well-maintained buildings on 1.89 acres with multiple end-use opportunities.

    4033 Geer Highway, Cleveland, SC 29635
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    Greenville Redevelopment Opportunity
    $449,609
    0.50 Acres

    Greenville Redevelopment Opportunity

    0.5-acre property in Greenville's evolving corridor, ideal for redevelopment.

    730 Wade Hampton Boulevard, Greenville, SC 29609
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    Renovated Office Building For Sale
    $599,000
    0.35 Acres

    Renovated Office Building For Sale

    Fully renovated office building with parking and road visibility.

    1320 Haywood Road, Greenville, SC 29615
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    Main Street Professional Office Space
    Contact for pricing
    0.10 Acres

    Main Street Professional Office Space

    Newly renovated office spaces overlooking Main Street, Greenville.

    200 N Main Street, Greenville, SC 29601
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    Prime Greenville Commercial Corner Lot
    $1,400,000
    0.72 Acres

    Prime Greenville Commercial Corner Lot

    High-visibility corner lot in vibrant Poinsett District near downtown.

    Poinsett Highway, Greenville, SC 29609
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    Downtown Greenville Acreage Opportunity
    $450,000
    0.52 Acres

    Downtown Greenville Acreage Opportunity

    Half-acre lot near Unity Park with limitless possibilities.

    315 S Hudson Street, Greenville, SC 29601
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    Greenville Office For Sale
    $895,000
    0.25 Acres

    Greenville Office For Sale

    Office property available for purchase in Greenville, South Carolina.

    204 Mills Avenue, Greenville, SC 29605
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    Charming Updated Office in Simpsonville
    Contact for pricing
    0.37 Acres

    Charming Updated Office in Simpsonville

    Prime location in Historic Downtown Simpsonville with rustic charm.

    312 S Main Street, Simpsonville, SC 29681
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    Greenville Office Space For Lease
    Contact for pricing
    0.10 Acres

    Greenville Office Space For Lease

    Centrally located office/studio space near downtown Greenville.

    1322 E Washington Street, Greenville, SC 29607
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    Unrestricted Land with Development Potential
    $595,000
    5.77 Acres

    Unrestricted Land with Development Potential

    Approximately 5.7 acres of unrestricted land bordering a creek.

    419 Wood Road, Taylors, SC 29687
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    Greer Commercial Corner Acreage
    $750,000
    3.51 Acres

    Greer Commercial Corner Acreage

    3.5 acre commercial site with high traffic frontage.

    13001 E Wade Hampton Boulevard, Greer, SC 29651
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    Prime Land Near Downtown Greenville
    $475,000
    0.38 Acres

    Prime Land Near Downtown Greenville

    Land opportunity minutes from downtown Greenville with endless possibilities.

    308 Sullivan Street, Greenville, SC 29605
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    Piedmont Corner Lot For Sale
    $399,000
    1.83 Acres

    Piedmont Corner Lot For Sale

    1.83 acre corner lot with development potential in Piedmont, SC.

    371 Bessie Road, Piedmont, SC 29673
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    Greenville Commercial Land on Wade Hampton
    $500,000
    0.85 Acres

    Greenville Commercial Land on Wade Hampton

    0.85-acre commercial lot near Downtown Greenville, zoned C-3.

    00 Wade Hampton Boulevard, Greenville, SC 29601
    View details
    Retail Opportunity in High-Traffic Area
    $990,000
    0.57 Acres

    Retail Opportunity in High-Traffic Area

    Prime retail space near popular shopping and dining establishments.

    2813 Wade Hampton Boulevard, Taylors, SC 29687
    View details

    Greenville County, SC Commercial Real Estate Investment Opportunities Market Analysis

    Explore 5000+ commercial real estate for sale in Greenville County, SC, showcased through 429 active listings on our real estate platform. These investment opportunities span a total of 11,756,246 square feet of properties for sale, with an estimated market value of $248,744,391.

    Sale prices for business properties in Greenville County, SC start at $200,000, averaging $1,739,471, and reaching up to $7,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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