Simpsonville, SC Commercial real estate for sale

Updated: Sep 24

Storefront with Multipurpose Room

414 W Fernwood Road, Simpsonville, SC 29681

$950,000

0.38 AC lot

33' x 30' exercise or multipurpose room
0.38‑acre parcel
CVS Pharmacy directly across from the property
Brick construction with carpet flooring
Forced‑air electric heat and public water

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Updated: Jun 18

Commercial Land Near Retail Anchors

1212 W Georgia Road, Simpsonville, SC 29680

$1,500,000

4.53 AC lot

4.53+/- total acres across two adjoining commercial parcels
1.16‑acre lot includes an existing brick ranch
Adjacent 3.37+/- acre lot includes an outbuilding
Currently zoned B‑G within the City of Simpsonville
Approximately 460 feet from W. Georgia Rd and Standing Springs Rd

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Commercial Land with Road Frontage

W Georgia Road, Simpsonville, SC 29680

$1,295,000

4.00 AC lot

BG-zoned commercial land with substantial road exposure and nearby retail, healthcare, dining, and automotive services.

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Historic Creative Workspace

300 South St, Simpsonville, SC 29681

$1,750,000

8,082 sqft

Flexible commercial layout with open work areas, private rooms, offices, restrooms, a breakroom, and an outdoor patio.

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Waterfront Land with River Frontage

2869 W Georgia Road, Simpsonville, SC 29680

$499,000

3.30 AC lot

R-S-zoned tract with road frontage, river frontage, and public utilities nearby.

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B-G Zoned Commercial Land

1212 W Georgia Road, Simpsonville, SC 29680

$1,500,000

4.53 AC lot

B-G-zoned commercial land with existing improvements and electric service available.

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Innovation District Commercial Land

Harrison Bridge Road, Simpsonville, SC 29680

$873,910

2.81 AC lot

Commercial land with available utilities near the Harrison Bridge Road and Fairview Road intersection.

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Automotive Repair and Storage Facility

1010 NE Main Street, Simpsonville, SC 29681

$1,175,000

2,850 sqft 0.53 AC lot

Automotive repair shop with detached storage and 16 parking spaces on C-2 zoned frontage.

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Land in Fairview Rd Area

3990 Grandview Drive, Simpsonville, SC 29680

$700,000

1.17 AC lot

Two parcels of land in Simpsonville's Fairview Rd area.

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Land in Fairview Rd Area

3989 Grandview Drive, Simpsonville, SC 29680

$1,300,000

2.08 AC lot

Approximately 2.08 acres in Simpsonville's Fairview Rd area.

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Simpsonville Commercial Building For Sale

313 N Main Street, Simpsonville, SC 29681

$3,995,000

24,000 sqft

24,000 SF building in Simpsonville, SC, renovated in 2013.

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Wooded Land in Simpsonville, SC

626 New Harrison Bridge Road, Simpsonville, SC 29680

$1,000,000

32.40 AC lot

32-acre wooded land with water access for development projects.

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Retail Space in Shopping Center

659 Fairview Road, Simpsonville, SC 29680

Contact for pricing

4,486 sqft

Retail space within a shopping center with Business-General zoning and access via a signalized intersection.

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Medical Office Space with Existing Buildout

717 NE Main St, Simpsonville, SC 29681

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3,000 sqft

Existing chiropractic-office configuration supports continued professional use or conversion for legal and accounting services.

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Retail Building with Storage Shed

1010 NE Main Street, Simpsonville, SC 29681

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2,000 sqft 0.53 AC lot

C-2-zoned retail property with an accompanying storage shed.

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Second-Generation Medical Office

35 Ray E Talley Ct, Simpsonville, SC 29680

Contact for pricing

7,880 sqft

Well-maintained medical and office space in Simpsonville’s retail corridor near I-385 access.

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Land with League Road Frontage

00 Cooper Lake Road, Simpsonville, SC 29681

$850,000

9.84 AC lot

About 9.84 acres in two noncontiguous tracts with League Road frontage, level-to-gently sloping terrain, and recorded restrictions.

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Simpsonville Retail Space

615 NE Main Street, Simpsonville, SC 29680

$2,307,000

The property is located on NE Main Street in Simpsonville, South Carolina.

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Bojangles Corporate Guaranteed Investment

208 Harrison Bridge Road, Simpsonville, SC 29680

Contact for pricing

3,808 sqft

New 15-year NNN lease Bojangles in Simpsonville, SC.

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Fully Leased Retail Strip Center

15 Ray E Talley Ct, Simpsonville, SC 29681

Contact for pricing

6,300 sqft

Fully leased retail strip center anchored by Subway and Great Clips along Fairview Road.

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Business-Industrial Land Lot

3009 Kemet Way, Simpsonville, SC 29681

$350,000

1.06 AC lot

1.06-acre commercial lot with driveway access, public water availability, and Business-Industrial zoning in Simpsonville, SC.

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C-2 Commercial Land

108 Harrison Bridge Rd, Simpsonville, SC 29681

$2,900,000

Commercial land along Harrison Bridge Rd with C-2 zoning and visibility from I-385.

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Warehouse with Three-Phase Heavy Power

502 Palmetto Dr, Simpsonville, SC 29681

Contact for pricing

18,000 sqft

Warehouse with office space, multiple dock and drive-in doors, suspended gas heat, and heavy 480-volt three-phase power.

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Industrial Property with Rail Service

300 South Main Street, Simpsonville, SC 29681

Contact for pricing

22.00 AC lot

A multi-tenant industrial campus combines warehouse and office space with outdoor storage and rail-service capability.

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Simpsonville, SC Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Simpsonville, SC, showcased through 36 active listings on our real estate platform. These investment opportunities span a total of 84,031 square feet of properties for sale, with an estimated market value of $26,794,910.

Sale prices for business properties in Simpsonville, SC start at $350,000, averaging $1,410,258, and reaching up to $3,995,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Simpsonville, SC CRE market trends — vacancy, lease rates and price per SF, updated monthly

Neighborhood	Average Price
29680	$1.5M
29681	$1.5M

Neighborhood

Average Price

29680

$1.5M

29681

$1.5M