Guadalupe County, TX Commercial Real Estate for Lease

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Two-Story Office Building
Two-Story Office Building

109 N River Street, Seguin, TX 78155

$4,888/Mo
4,250 sqft

Two-story masonry office building with multiple entryways, large display windows, and parking for patrons.

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Office Building with Large Conference Room
Office Building with Large Conference Room

3040 W Interstate 10 Expressway, Seguin, TX 78155

$3,800/Mo
2,442 sqft

Office building visible on IH 10 with eight offices and a very large conference room.

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Versatile Flex Space in Seguin
Versatile Flex Space in Seguin

1012 Schriewer, Seguin, TX 78155

$4,500/Mo
16,555 sqft 2.61 AC lot

16,555 sq ft flex building on 2.61 acres.

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Commercial Space Near Downtown Seguin
Commercial Space Near Downtown Seguin

200-637 W Court St, Seguin, TX 78155

$2,000/Mo
3,000 sqft

Commercial space for lease near downtown Seguin, Texas.

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Office Suite with Private Office and Restroom
Office Suite with Private Office and Restroom

217 S River St 200, Seguin, TX 78155

$850/Mo

Luxury office suites offer a private office and restroom, with updated interiors and abundant natural light.

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Seguin Industrial Warehouse Space
Seguin Industrial Warehouse Space

299 Navarro Drive #1, Seguin, TX 78155

$1,875/Mo
1,500 sqft

1500 sqft industrial warehouse with modern office space for lease.

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Updated Medical Office Condominium
Updated Medical Office Condominium

515 N King St 108, Seguin, TX 78155

$2,285/Mo

Turnkey, freshly updated office condo available July 1, 2026, positioned for medical or other professional use near the hospital.

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Updated Professional Office Condominium
Updated Professional Office Condominium

108-515 N King St, Seguin, TX 78155

$2,285/Mo

Updated office condo available July 1, 2026, suited for medical or other professional office users.

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Downtown Loft Office Workspace
Downtown Loft Office Workspace

A-103 W Walnut St, Seguin, TX 78155

$1,500/Mo
1,254 sqft

Upstairs open-concept loft with soaring ceilings, large windows, and central HVAC for work or live-work use.

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Renovated Office Suite with Reception
Renovated Office Suite with Reception

128 S Moss St, Seguin, TX 78155

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1,400 sqft

Renovated 1,400 SF office suite with a reception area, four private offices, and a coffee nook.

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Turnkey Restaurant with Patio and Parking
Turnkey Restaurant with Patio and Parking

983 N Highway 123, Seguin, TX 78155

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7,960 sqft 1.49 AC lot

Turnkey restaurant opportunity with patio, fully equipped kitchen, and strong visibility across a high school campus.

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Commercial Building with Drive-Up Parking
Commercial Building with Drive-Up Parking

410 E Gonzales St, Seguin, TX 78155

$2,800/Mo

Functional commercial building with drive-up parking available for rent.

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Freestanding Industrial Warehouse
Freestanding Industrial Warehouse

1141 Guadalupe Drive, Cibolo, TX 78108

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8,750 sqft 0.67 AC lot

Freestanding industrial warehouse with dock-high and grade-level loading, small office build-out, and fenced yard on 0.67 acres.

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Medical Office Space For Rent
Medical Office Space For Rent

412 N King St, Seguin, TX 78155

$1,500/Mo
0.30 AC lot

Move-in ready medical office space near Guadalupe Regional Medical Center.

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Commercial Space Near Downtown Seguin
Commercial Space Near Downtown Seguin

637 W. Court St. Ste. 200, Seguin, TX 78155

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1,250 sqft

Commercial space available for lease near downtown Seguin, Texas.

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Warehouse with Truck Court
Warehouse with Truck Court

17414 Triton Dr, Schertz, TX 78154

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92,000 sqft

Warehouse facility offers 24' clear height, dock high doors with levelers, and dedicated trailer parking in a 115' truck court.

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Versatile Commercial Leasing Opportunity
Versatile Commercial Leasing Opportunity

7049 FM 1044, Marion, TX 78124

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9,000 sqft

Premier commercial complex with flexible build-out options and ample yard space.

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Retail Space Near Walmart Supercenter
Retail Space Near Walmart Supercenter

6032 FM 3009, Schertz, TX 78154

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29,568 sqft

4,000 SF retail space at IH-35 & FM 3009.

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Industrial Warehouse with Office Space
Industrial Warehouse with Office Space

3391 FM465, Seguin, TX 78155

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11,950 sqft

11,950 SF warehouse with office, quick I-10 access.

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New Retail Buildings with Drive-Through
New Retail Buildings with Drive-Through

551 WOODLAND OAKS DRIVE, Schertz, TX 78154

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25,000 sqft

Two-building retail property offers direct access, patio space, and drive-through configurations.

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Northeast Submarket Flex Space
Northeast Submarket Flex Space

6696 Tri County Parkway, Schertz, TX 78154

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7,252 sqft

Class A construction with office space and dock high doors.

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Industrial Warehouse with Office Space
Industrial Warehouse with Office Space

3701 Auxiliary Airport Rd, Seguin, TX 78155

$2,750/Mo

Warehouse with offices, kitchen, bathroom, and roll-up doors.

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Schertz Warehouse with IH-35 Access
Schertz Warehouse with IH-35 Access

5755 Tri County Parkway, Schertz, TX 78154

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55,025 sqft

Warehouse space with convenient access to IH-35 and Tri-County Parkway.

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Schertz Warehouse Space Available
Schertz Warehouse Space Available

5925 Tri County Parkway, Schertz, TX 78154

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244,800 sqft

244,800 SF warehouse space for lease in Schertz, TX.

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