Guadalupe County, TX Commercial Real Estate for Lease

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Two-Story Office Building
Two-Story Office Building

109 N River Street, Seguin, TX 78155

$4,888/Mo
4,250 sqft 0.25 AC lot

Historic downtown office property with flexible rooms, display windows, multiple entrances, and patron parking.

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Versatile Flex Space in Seguin
Versatile Flex Space in Seguin

1012 Schriewer, Seguin, TX 78155

$4,500/Mo
16,555 sqft 2.61 AC lot

16,555 sq ft flex building on 2.61 acres.

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Commercial Space Near Downtown Seguin
Commercial Space Near Downtown Seguin

200-637 W Court St, Seguin, TX 78155

$2,000/Mo
3,000 sqft

Commercial space for lease near downtown Seguin, Texas.

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Office Suite with Private Office and Restroom
Office Suite with Private Office and Restroom

217 S River St 200, Seguin, TX 78155

$850/Mo

Luxury office suites offer a private office and restroom, with updated interiors and abundant natural light.

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Updated Office Unit with Reception Area
Updated Office Unit with Reception Area

100-128 S Moss St, Seguin, TX 78155

$2,100/Mo
11,200 sqft

Professional suite offers private offices, natural light, and recent interior improvements.

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Flexible Office Unit
Flexible Office Unit

310 Pfeil Rd, Cibolo, TX 78108

$4,000/Mo

Commercial space with an adaptable layout for office, retail, daycare, or professional service use, subject to zoning and permitting.

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Updated Medical Office Condominium
Updated Medical Office Condominium

515 N King St 108, Seguin, TX 78155

$2,285/Mo

Turnkey, freshly updated office condo available July 1, 2026, positioned for medical or other professional use near the hospital.

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Updated Professional Office Condominium
Updated Professional Office Condominium

108-515 N King St, Seguin, TX 78155

$2,285/Mo

Updated office condo available July 1, 2026, suited for medical or other professional office users.

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Open-Concept Live-Work Loft
Open-Concept Live-Work Loft

103 W Walnut St A, Seguin, TX 78155

$1,500/Mo
1,254 sqft

Upstairs workspace with flexible planning, central HVAC, supplemental window units, and strong natural light from expansive windows.

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New Retail Buildings with Drive-Through
New Retail Buildings with Drive-Through

551 WOODLAND OAKS DRIVE, Schertz, TX 78154

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25,000 sqft

Two-building retail property offers direct access, patio space, and drive-through configurations.

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Turnkey Restaurant with Patio and Parking
Turnkey Restaurant with Patio and Parking

983 N Highway 123, Seguin, TX 78155

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7,960 sqft 1.49 AC lot

Turnkey restaurant opportunity with patio, fully equipped kitchen, and strong visibility across a high school campus.

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Commercial Building with Drive-Up Parking
Commercial Building with Drive-Up Parking

410 E Gonzales St, Seguin, TX 78155

$2,800/Mo

Functional commercial building with drive-up parking available for rent.

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Medical Office Space
Medical Office Space

16977 Interstate 35 N, Schertz, TX 78154

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2,347 sqft

Space is offered under a sublease arrangement.

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Flex Space with Fenced Yard
Flex Space with Fenced Yard

3000 W US Highway 90, Seguin, TX 78155

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8,825 sqft 1.00 AC lot

Office, warehouse, and operational areas support a range of commercial business functions.

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Two-Building Warehouse Complex
Two-Building Warehouse Complex

5440 S Highway 123 Byp, Seguin, TX 78155

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13,255 sqft 1.80 AC lot

Two-building warehouse property with a fenced yard, grade-level access, and three-phase power.

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Commercial Land Near HEB
Commercial Land Near HEB

611 FM1103, Cibolo, TX 78108

Contact for pricing
2 sqft 2.30 AC lot

Commercial land in Cibolo with access to FM 78 and Cibolo Valley Drive.

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Versatile Commercial Leasing Opportunity
Versatile Commercial Leasing Opportunity

7049 FM 1044, Marion, TX 78124

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9,000 sqft

Premier commercial complex with flexible build-out options and ample yard space.

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Former Day Care Center
Former Day Care Center

1271 Oak St, Schertz, TX 78154

$15 SF/Yr

Visible commercial space with frontage near FM 1518 and convenient access to surrounding Schertz amenities.

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Retail Space Near Walmart Supercenter
Retail Space Near Walmart Supercenter

6032 FM 3009, Schertz, TX 78154

Contact for pricing
29,568 sqft

4,000 SF retail space at IH-35 & FM 3009.

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Gated Flex Space with Loading Doors
Gated Flex Space with Loading Doors

112 Commercial Pl, Schertz, TX 78154

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4,875 sqft

Metal construction combines warehouse, office, and restroom areas with controlled yard access.

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Commercial Land with Retail Improvements
Commercial Land with Retail Improvements

6262 Navarro Cv, Seguin, TX 78155

Contact for pricing
2,100 sqft

Retail-oriented commercial acreage includes an established convenience store and a drive-through end-cap configuration.

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Northeast Submarket Flex Space
Northeast Submarket Flex Space

6696 Tri County Parkway, Schertz, TX 78154

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7,252 sqft

Class A construction with office space and dock high doors.

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Office Warehouse Space For Lease
Office Warehouse Space For Lease

303 Navarro Drive, Seguin, TX 78155

$2,758/Mo

Office warehouse with bay door, restroom, and small office space.

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Industrial Warehouse with Office Space
Industrial Warehouse with Office Space

3701 Auxiliary Airport Rd, Seguin, TX 78155

$2,750/Mo
1.87 AC lot

Warehouse with offices, kitchen, bathroom, and roll-up doors.

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