Starr County, TX Commercial real estate for Rent & Lease

Multi-Suite Retail Space

511 2nd Street, Rio Grande City, TX 78582

$1,000/Mo

3,888 sqft Built 1992

Highway access

Commercial suites with on-street and off-street parking near Expressway 83.

8 parking spaces

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Highway-Frontage Commercial Land

FM 3167, Rio Grande City, TX 78582

$1,500/Mo

34 acres Built 2000

Cleared commercial acreage with fencing, a perimeter road, and water service extending toward the center of the property.

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Medical Office Suite

5322 E Us Highway 83 #C-4, Rio Grande City, TX 78582

$3,039/Mo

3,039 sqft Built 2004

Highway access

A room-diverse space in an established medical plaza includes dedicated diagnostic, treatment, and administrative areas.

160 parking spaces

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Medical Office Suite

5322 E Us Highway 83 #C-5, Rio Grande City, TX 78582

$3,003/Mo

3,003 sqft Built 2004

Highway access

A multi-room layout includes a reception area, office, breakroom, and separate restroom facilities.

160 parking spaces

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Medical Office Suite

5322 E Us Highway 83 #C-2, Rio Grande City, TX 78582

$2,925/Mo

2,925 sqft Built 2004

Highway access

Available for lease, the multi-room space includes reception, private offices, workstations, storage, and two restrooms.

160 parking spaces

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Medical Office Suite

C-5-5322 E Us Highway 83, Rio Grande City, TX 78582

$3,003/Mo

3,003 sqft

Highway access Road access

A multi-room commercial suite includes reception, office, breakroom, and control room areas.

160 parking spaces

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Medical Office Suite

C-2-5322 E Us Highway 83, Rio Grande City, TX 78582

$2,925/Mo

2,925 sqft

Highway access Road access

A multi-room configuration includes private offices, five workstations, and two restrooms.

160 parking spaces

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Retail Suite with Drive-Through

5322 E Us Highway 83 #C-1, Rio Grande City, TX 78582

$3,816/Mo

3,816 sqft Built 2004

Highway access

A former pharmacy occupies a suite in a medical plaza on US Highway 83.

160 parking spaces Drive-thru Flexible layout Excellent visibility

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Medical Office Suite

C-4-5322 E Us Highway 83, Rio Grande City, TX 78582

$3,039/Mo

3,039 sqft

Highway access Road access

A multi-room clinical layout includes a reception lobby, radiology and lab rooms, exam areas, and dedicated support spaces.

160 parking spaces

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Medical Office Suite

5326 E Us Highway 83 #A-1, Rio Grande City, TX 78582

$4,032/Mo

3,150 sqft Built 2007

Positioned within a medical plaza, the space offers a healthcare-focused setting in Rio Grande City.

135 parking spaces

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Downtown Retail Space

300 E Main Street E, Rio Grande City, TX 78582

$9,600/Mo

10,829 sqft Built 1950

The property is in downtown Rio Grande City and carries C zoning.

30 parking spaces

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Retail Suite

302 E 2nd Street #B, Rio Grande City, TX 78582

$2,900/Mo

2,900 sqft Built 1985

The commercial space is near City Hall, banks, and restaurants.

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Retail Suite in Planned Center

4791 Us Highway 83 #102, Rio Grande City, TX 78582

$5,880/Mo

1,680 sqft 3,850 GLA Built 2026

Highway access

A future retail development on US Highway 83 will sit beside Dutch Bros and near national retailers.

25 parking spaces

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Office Suites for Lease

511 2nd Street, Rio Grande City, TX 78582

$1,000/Mo

15–25 people 3,888 sqft

Office suites for lease near Expressway 83, with flexible space for office, medical, and wellness uses.

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Planned Strip Center Retail Space

4791 Us Highway 83 #101, Rio Grande City, TX 78582

$7,595/Mo

2,170 sqft Built 2026

Highway access

Suite 101 is part of a proposed retail development near Dutch Bros and national retailers along US Highway 83.

25 parking spaces

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Warehouse With Loading Dock

4852 E Highway 83, Roma, TX 78584

$7,500/Mo

14,000 sqft 14,000 sqft warehouse 2 buildings

Industrial warehouse with trailer-capable loading infrastructure and two distinct warehouse areas.

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Premier Plaza Retail Unit

2-216 N Fm 3167, Rio Grande City, TX 78582

$1,650/Mo

12,100 sqft

Commercial space suited to retail, professional office, or service-oriented business uses.

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Versatile Retail Space

B-302 E 2nd St, Rio Grande City, TX 78582

$2,900/Mo

2,900 sqft

Commercial suite near City Hall, banks, restaurants, and other everyday amenities.

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New Construction Strip Center

4791 E US Highway 83, Rio Grande City, TX 78582

$39 SF/Yr

Highway access

Retail space fronts US Highway 83 beside Dutch Bros in Rio Grande City, with access to the area’s primary east-west route.

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High-Traffic Retail Space

2500 East US Highway 83, Rio Grande City, TX 78582

Contact for pricing

15,518 sqft Built 1992

Retail space for lease on a high-traffic US Highway 83 corridor adjacent to Lacks Furniture.

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Flex Space with Warehouse

1999 Embassy Street, Rio Grande City, TX 78582

$5,500/Mo

1,000 sqft 1,300 sqft office 17,000 sqft warehouse

A mixed office and warehouse layout includes enclosed and open areas, plus covered concrete space.

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Commercial Land at Grocery-Anchored Center

4023 US-83, Rio Grande City, TX 78582

Contact for pricing

Commercial land within Starr Plaza, anchored by HEB and Marshalls and located on US 83 near the Mexico bridge.

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Medical Office Space in Plaza

A-1-5326 E Us Highway 83, Rio Grande City, TX 78582

$4,032/Mo

3,150 sqft

The suite is situated in Rio Grande City near municipal offices and several retail businesses.

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Flexible Retail Space with Office Use

B-1208 N Grant St, Roma, TX 78584

$400/Mo

720 sqft

Commercial unit suitable for either office or retail operations along US Hwy 83.

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