For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
Price
Price range
$
$
Size
Property size / sq.ft.

Lancaster County, SC Commercial Real Estate for Lease

27 results
List
Map
Arlington Townhome with Modern Amenities
$1,925 / Mo
1,353 SF

Arlington Townhome with Modern Amenities

6309 Rhodins Ln, Indian Land, SC 29707

3-bedroom, 2.5-bathroom townhome in desirable Arlington neighborhood near Ballantyne.

  • Desirable Arlington neighborhood location.
  • Open floorplan connecting family room and dining area with fireplace.
  • Modern kitchen with GRANITE countertops and STAINLESS STEEL appliances.
  • Access to neighborhood clubhouse and pool.
  • Conveniently located near Hwy 160 and Ballantyne area.
Updated: Jul 16, 2025
View details
Indian Land Retail Center
Contact for pricing
17,400 SF

Indian Land Retail Center

8918 Charlotte Hwy, Indian Land, SC 29707

Grocery-anchored spaces available now

  • Grocery‑anchored retail center with nine available spaces (1,200‑4,800 SF).
  • Located in one of the fastest‑growing South Carolina communities within the Charlotte MSA, experiencing over 5% projected annual population growth.
  • High‑traffic location on Highway 521 (29,700 VPD), with nearby Costco and Target under development.
  • 1⁄2 mile from a proposed 100‑bed MUSC hospital.
  • Strong retail competition in the area, including Harris Teeter, Publix, Food Lion, Walmart, and other major retailers.
Updated: Dec 11, 2024
View details
360 Fort Mill Pkwy
Contact for pricing
15,638 SF

360 Fort Mill Pkwy

Medical offices • 15,638 SF

360 Fort Mill Pkwy, Fort Mill, SC 29715
View details
1256 Highway 9 Byp
Contact for pricing
181,542 SF

1256 Highway 9 Byp

Retail properties • 181,542 SF

1256 Highway 9 Byp, Lancaster, SC 29720
View details
Fort Mill Medical Office Space
$28 SF/Yr
60,000 SF

Fort Mill Medical Office Space

Class A, 60,000 SF, Multiple Suites Available

986 Wellness Way, Fort Mill, SC 29715
View details
Class A Medical Office Space in Indian Land
$36 SF/Yr
31,000 SF

Class A Medical Office Space in Indian Land

Modern medical suites, ideal location, ample space.

8488 Charlotte Hwy, Fort Mill, SC 29707
View details
University Place Retail Center
Contact for pricing
12,800 SF

University Place Retail Center

Lancaster, SC: 8,000 SF Available

945-973 Highway 9 Byp, Lancaster, SC 29720
View details
South Square Retail Center - Lancaster, SC
Contact for pricing
44,350 SF

South Square Retail Center - Lancaster, SC

High-growth Lancaster, SC retail space.

0 Airport Rd And Barton Rd, Lancaster, SC 29720
View details
University Place Retail Opportunity
Contact for pricing
14,400 SF

University Place Retail Opportunity

Lancaster, SC: 6,000 SF Available

905-933 Highway 9 Byp, Lancaster, SC 29720
View details
Lancaster Retail Space - Hwy 200
Contact for pricing
2,322 SF

Lancaster Retail Space - Hwy 200

Prime Lancaster retail/office, 2322 SF.

100 Monroe Hwy, Lancaster, SC 29720
View details
Fort Mill Office Space Available
Contact for pricing
151,500 SF

Fort Mill Office Space Available

Class A Office Building, 3 Stories, Multiple Tenancies

8106 Calvin Hall Rd, Fort Mill, SC 29707
View details
Elite Edgewater Office Suites
$30 SF/Yr
28,000 SF

Elite Edgewater Office Suites

Modern Office Space, Flexible Sizes

9571 Charlotte Hwy, Indian Land, SC 29707
View details
Edgewater Corporate Park: Fort Mill, SC
Contact for pricing
14,496 SF

Edgewater Corporate Park: Fort Mill, SC

Class A Medical Office Space Available

1170 Edgewater Pkwy, Fort Mill, SC 29707
View details
Downtown Lancaster Office Space
$15 SF/Yr
3,360 SF

Downtown Lancaster Office Space

Prime Lancaster SC location, flexible spaces.

114 Gay St, Lancaster, SC 29720
View details
Fort Mill Executive Office Space
Contact for pricing
7,000 SF

Fort Mill Executive Office Space

Prime Office Suites Available, 1,600 SF Vacant

308 Springcrest Dr, Fort Mill, SC 29715
View details
Cross Creek Retail Center - Indian Land
Contact for pricing
2,150 SF

Cross Creek Retail Center - Indian Land

Prime Retail Space, 2,150 sq ft, 170 acres

8394 Charlotte Hwy, Indian Land, SC 29707
View details
Rosemont Park Office Suites
Contact for pricing
24,990 SF

Rosemont Park Office Suites

Fort Mill, SC Office Space Available

1245 Rosemont Dr, Fort Mill, SC 29707
View details
Mills Crossing Retail Center
Contact for pricing
48,102 SF

Mills Crossing Retail Center

Fort Mill, SC Shopping Center - Spaces Available

2351 Len Patterson Rd, Fort Mill, SC 29708
View details
Carolina Commons Retail Space
Contact for pricing
76,796 SF

Carolina Commons Retail Space

High-traffic retail space available now.

6285 Carolina Cmns Dr, Indian Land, SC 29707
View details
Mixed-Use Retail Space Available
Contact for pricing
8,377 SF

Mixed-Use Retail Space Available

Premier mixed-use project with retail, residential, and entertainment.

Charlotte Hwy & Redstone Dr, Indian Land, SC
View details
Class A Office Space Available
Contact for pricing
30,978 SF

Class A Office Space Available

120,000 SF Class A office space for rent.

1000 Corporate Ctr Way, Indian Land, SC
View details
Lancaster Medical/Office Space Available
$875,000
6,900 SF

Lancaster Medical/Office Space Available

Versatile space near MUSC Health Lancaster Medical Center.

980 N Woodland Dr, Lancaster, SC 29720
View details
Premier Mixed-Use Project Space
Contact for pricing
1,604 SF

Premier Mixed-Use Project Space

Mixed-use property with retail, restaurant, office, and residential spaces.

9695 Red Stone Dr, Indian Land, SC
View details
Retail Space Near Kiddie Academy
$28 SF/Yr
2,012 SF

Retail Space Near Kiddie Academy

Retail space available for lease near US-521.

1990 Zelkova Dr, Indian Land, SC
View details

Lancaster County, SC Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Lancaster County, SC with 43 listings featured on our commercial real estate exchange. The current inventory includes 5,476,581,000 square feet of properties with an estimated lease value of $154 SF/Yr.

Estimated lease rates for Commercial Real Estate in Lancaster County, SC begin at $15 SF/Yr, with an average of $25 SF/Yr and extend to $36 SF/Yr.

In Lancaster County, SC, current lease rates show:

  • Healthcare properties positioned at $27
  • Medical offices measuring $27
  • Office Properties & Spaces assessed at $27
  • Other healthcare properties calculated at $27
List
Map