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    South Portland, ME
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    South Portland, ME Commercial Real Estate for Lease

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    Portland, ME Cape Elizabeth, ME Scarborough, ME
    45 listings
    Class A Medical Building Space
    $25 SF/Yr
    3,099 SF
    Class A Medical Building Space

    100 Foden Road, South Portland, ME 4106

    Class A medical building with convenient highway access and ample parking.
    • Convenient location with direct access to Maine Turnpike, I‑95, and I‑295
    • High‑capacity surface parking lot with 260 spaces
    • Class A, 3‑story medical building
    • Building & Monument Signage Opportunities available
    • Campus‑like setting
    Updated: May 26
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    Versatile Office or Retail Space
    $2,000/Mo
    1,000 SF
    Versatile Office or Retail Space

    851 Sawyer St, South Portland, ME 4106

    1,000± SF space ideal for various business types.
    • Versatile 1,000± SF space suitable for office, retail, medical, or service businesses.
    • Convenient location along Route 77.
    • Dedicated off‑street parking.
    • Lease rate of $2,000/month MG (includes heat, water, & sewer).
    • Available immediately.
    Updated: May 5
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    Class A Office Sublease Available
    $15 SF/Yr
    7,599 SF
    Class A Office Sublease Available

    7,599±SF Class A office space for sublease in South Portland.

    500 Southborough Dr, South Portland, ME

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    South Portland Office Space Available
    $17 SF/Yr
    6,321 SF
    South Portland Office Space Available

    Office space for lease near Maine Mall and Portland Jetport.

    311 Darling Ave, South Portland, ME

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    Restaurant/Retail Space For Sublease
    $15 SF/Yr
    2,647 SF
    Restaurant/Retail Space For Sublease

    2,647± SF restaurant/retail space available for sublease.

    185 Cottage Rd., South Portland, ME

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    Retail Space Near Maine Mall
    $23 SF/Yr
    1,054 SF
    Retail Space Near Maine Mall

    Retail space with high visibility and ample parking available for lease.

    29 Western Ave, South Portland, ME

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    Retail Space in Cornerbrook Plaza
    $7 SF/Yr
    12,808 SF
    Retail Space in Cornerbrook Plaza

    High-performing retail center with flexible space and excellent accessibility.

    343 Gorham Rd, South Portland, ME

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    Corner Retail Building with Pylon Sign
    Contact for pricing
    20,700 SF
    Corner Retail Building with Pylon Sign

    Freestanding retail building on a corner lot with strong visibility and updated roof and HVAC for dependable occupancy.

    130 Western Ave, South Portland, ME 4106

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    Class A Office/Medical Building
    $13 SF/Yr
    4,646 SF
    Class A Office/Medical Building

    Class A office/medical building with suites available for lease.

    175 Running Hill Road, South Portland, ME

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    South Portland Industrial/Flex Space
    $7 SF/Yr
    2,400 SF
    South Portland Industrial/Flex Space

    2,400± SF industrial/flex space for lease in South Portland.

    1 Runway Rd, South Portland, ME 4106

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    Class-A Office Suite For Lease
    $16 SF/Yr
    5,121 SF
    Class-A Office Suite For Lease

    Full-floor office suite in South Portland's Maine Mall area.

    30 Long Creek Dr, South Portland, ME

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    Updated Medical Spa Space Available
    $20 SF/Yr
    4,200 SF
    Updated Medical Spa Space Available

    Recently updated medical spa, salon, or medical space for lease.

    198 Maine Mall Rd, South Portland, ME 4106

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    South Portland Industrial Flex Space
    $2,350/Mo
    1,875 SF
    South Portland Industrial Flex Space

    Flexible industrial space in South Portland, minutes from I-295.

    130 Thadeus St, South Portland, ME

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    Retail/Office Space For Lease
    $24 SF/Yr
    1,700 SF
    Retail/Office Space For Lease

    Retail/office space in high-traffic South Portland location.

    209 Western Ave, South Portland, ME

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    Industrial Building Near Maine Mall
    $15 SF/Yr
    5,700 SF
    Industrial Building Near Maine Mall

    5,700± SF industrial building with office space for lease.

    2092 Broadway, South Portland, ME

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    South Portland Office Space Available
    $10 SF/Yr
    1,812 SF
    South Portland Office Space Available

    Office space for lease in landmark South Portland building.

    100 Brickhill Avenue, South Portland, ME

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    Class A Office Space Available
    Contact for pricing
    1,323 SF
    Class A Office Space Available

    Class A office building with ample parking and professional landscaping.

    778 Main Street, South Portland, ME 4106

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    Corner Office Suite For Rent
    $13 SF/Yr
    4,040 SF
    Corner Office Suite For Rent

    4,040± SF office suite with ample free parking.

    202 Gannett Dr, South Portland, ME

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    Class A Office Suite Available
    $13 SF/Yr
    3,765 SF
    Class A Office Suite Available

    3,765 SF office suite for lease in South Portland.

    82 Running Hill Road, South Portland, ME 4106

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    Turn-Key Restaurant in Knightville
    $9 SF/Yr
    6,006 SF
    Turn-Key Restaurant in Knightville

    Impeccable 6006 SF restaurant space available for immediate occupancy.

    60 Ocean St, South Portland, ME

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    Freestanding Restaurant/Retail Building in Maine
    Contact for pricing
    6,250 SF
    Freestanding Restaurant/Retail Building in Maine

    6,250 SF restaurant/retail building in Maine Mall trade area.

    465 Maine Mall Rd, South Portland, ME 4106

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    Maine Mall Retail Space Available
    Contact for pricing
    4,768 SF
    Maine Mall Retail Space Available

    Retail space near Maine Mall, suitable for various businesses.

    50 Maine Mall Rd, South Portland, ME 4106

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    Industrial Facility with Modern Office
    Contact for pricing
    10,654 SF
    Industrial Facility with Modern Office

    Well-maintained industrial and office space near I-95 and Jetport.

    76 Darling Ave, South Portland, ME 4106

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    South Portland Office Space Available
    $13 SF/Yr
    2,500 SF
    South Portland Office Space Available

    2,500± SF office space for lease in South Portland.

    141 Main St, South Portland, ME

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    South Portland, ME Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in South Portland, ME with 45 listings featured on our commercial real estate exchange. The current inventory includes 399,699 square feet of properties with an estimated lease value of $630 /Mo.

    Estimated lease rates for Commercial real estate in South Portland, ME begin at $7 SF/Yr, with an average of $17 SF/Yr and extend to $28 SF/Yr.
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    Most Searched ZIP Codes in South Portland, ME

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    • 04101

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