Medical Space

Portland, ME Medical Office Space for Lease

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South Portland, ME Falmouth, ME Scarborough, ME Westbrook, ME Yarmouth, ME Freeport, ME Gorham, ME Saco, ME
Retail/Office Space on Marginal Way
Updated: Nov 24, 2025
Retail/Office Space on Marginal Way

191 Marginal Way, Portland, ME 04101

$38 SF/Yr
High‑traffic location with Marginal Way frontage and exposure to I‑295.
Excellent walkability score of 93** in a mixed‑use building.
Anchor tenants include ConvenientMD, Dunkin’, Thrive Dental Studio and PetMedic.
Suitable for retail, office, and medical users.
Close proximity to I‑295 on/off ramps.
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Based on your search, we've compiled 6 Potential Opportunities for your consideration. Besides 1 Active listings in Portland, ME, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Medical Office Space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

First-Floor Medical Office Space
First-Floor Medical Office Space

500 Route 1, Yarmouth, ME 04096

$20 SF/Yr
2,000 sqft

First-floor office space with natural light and frontage suited to dental or medical practice use.

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Medical Office Condos
Medical Office Condos

25 Long Creek Drive, South Portland, ME 04106

Contact for pricing
6,230 sqft

Flexible office condo space with daylight lower level suited for medical, dental, wellness, and clinical services.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

10 Q St, South Portland, ME 04106

Contact for pricing
2,250 sqft

Prime medical office space with exam rooms, waiting area, and full handicap accessibility.

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Ground-Floor Medical Office Space
Ground-Floor Medical Office Space

45 Forest Falls Dr, Yarmouth, ME 04096

Contact for pricing
2,400 sqft 1.60 AC lot

Class A professional suite with shared paved parking, an open layout, reception area, kitchenette, and two private accessible bathrooms.

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Similar Spaces for Sale in Portland, ME

Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

Office Building with Detached Garage
Office Building with Detached Garage

930 Forest Ave, Portland, ME 04103

$575,000
1,940 sqft

Dutch Colonial layout offers adaptable office configuration with off-street parking.

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Portland, ME Medical Office Space Lease Rates & Market Statistics

Browse 1 Medical Office Space listing for lease in Portland, ME on Realmo, a commercial real estate marketplace serving the Portland area.

Asking lease rates for Medical Office Space in Portland start at $38 SF/Yr, average $38 SF/Yr, and reach $38 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $38 SF/Yr, the local average runs 48% above Maine's state average of $25.75 SF/Yr.

Portland accounts for 14% of the 7 medical office space listings currently available across Cumberland County, where nearby markets include South Portland and Yarmouth. Medical Office Space is one of the more limited space types in Portland, with just 1 listing currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (26 listings) and Office buildings (10 listings) elsewhere in the Portland market.

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