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    South Portland, ME
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    South Portland, ME Medical Office Space for Sale

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    Portland, ME Lewiston, ME Bangor, ME
    South Portland Medical Investment Opportunity
    $4,327,286
    7,424 SF

    South Portland Medical Investment Opportunity

    254 Western Ave, South Portland, ME

    Long-term NNN investment with a strong healthcare tenant.

    • Best‑in‑class Tenant: Paradigm Oral Health, a large and growing DSO with 75+ locations.
    • BlackRock Subsidiary: Majority interest acquired by BlackRock, indicating financial strength and stability.
    • ±14.9 Year NNN Investment: Enjoy long‑term passive income.
    • 3% Annual Rental Increases: Growing cash flow and hedge against inflation.
    • Healthcare Real Estate: Recession and e‑commerce resistant investment.
    Updated: Oct 29, 2025
    View details
    Professional Condo Near Maine Mall
    $925,000
    4,530 SF

    Professional Condo Near Maine Mall

    25B Long Creek Drive, South Portland, ME 4106

    Office space ideal for medical, dental, wellness, or clinical services.

    • Ideal office space for medical, dental, wellness, or clinical services.
    • Convenient location near Western Avenue and the Maine Mall with easy highway access (I‑95 and I‑295).
    • Turnkey and well‑maintained building.
    • Ample parking for patients, clients, and staff.
    • 4,530‑6,230±SF professional condo.
    Updated: Feb 3
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    Medical Outpatient Portfolio For Sale
    $1,154,664
    4,952 SF

    Medical Outpatient Portfolio For Sale

    Two-property medical portfolio fully leased to Straine Dental Management.

    25 Long Creek Drive, South Portland, ME 4106
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    Medical Office Space For Sale
    $3,800,000
    19,188 SF

    Medical Office Space For Sale

    19,188 SF medical office space on 2.61 acres.

    244 Western Ave, South Portland, ME 4106
    View details
    Based on your search, we've compiled 14 Potential Opportunities for your consideration. Besides 4 Active listings in South Portland, ME, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    York, ME Office Suite
    $249,900
    1,014 SF

    York, ME Office Suite

    Bright, renovated office suite in established medical building.

    1 Brickyard Lane, York, ME 03909
    View details
    York Village Commercial Condo For Sale
    $159,000
    441 SF

    York Village Commercial Condo For Sale

    Commercial condo in historic York Village with high visibility.

    298 York Street, York, ME 03909
    View details
    Rochester Medical/Office Condo For Sale
    $110,000
    1,515 SF

    Rochester Medical/Office Condo For Sale

    1,515+ SF medical/office condo near Frisbie Memorial Hospital.

    161 Rochester Hill Rd, Rochester, NH
    View details
    Rochester Medical/Office Condo For Sale
    $325,000
    3,134 SF

    Rochester Medical/Office Condo For Sale

    3,134 SF medical/office condo near Frisbie Memorial Hospital.

    163 Rochester Hill Rd, Rochester, NH 3867
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Norwich Commercial Parcel For Sale
    $101,000

    Norwich Commercial Parcel For Sale

    Multi-use commercial land parcel in a convenient Norwich location.

    171 Otrobando Ave, Norwich, CT 6360
    View details
    Waterbury Commercial Corner Lot
    $199,000
    0.24 Acres

    Waterbury Commercial Corner Lot

    0.24 acre corner lot zoned for various commercial uses.

    3280 E Main Street, Waterbury, CT 06705
    View details
    Prime Commercial Land on Route 376
    $110,000
    20.30 Acres

    Prime Commercial Land on Route 376

    20.3 acres of commercial land in Wappingers Falls, NY.

    Rt-376 lot: 372686, Wappingers Falls, NY 12590
    View details
    East Moriches Commercial Land Parcel
    $1,289,000
    1.45 Acres

    East Moriches Commercial Land Parcel

    1.45 acre commercial land with permits pending for wellness space.

    34-41 Montauk Highway, East Moriches, NY 11940
    View details

    Off-Market Properties in South Portland, ME

    Consider similar Off-Market properties in South Portland, ME. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    25 Long Creek Dr

    25 Long Creek Dr

    Medical Office Space • 4,532 SF
    Value Estimation by Request
    25 Long Creek Dr, South Portland, ME 04106
    View details
    25 Long Creek Dr

    25 Long Creek Dr

    Medical Office Space • 16,150 SF
    Value Estimation by Request
    25 Long Creek Dr, South Portland, ME 04106
    View details

    South Portland, ME Medical Office Space Investment Opportunities Market Analysis

    Explore 6 medical office space for sale in South Portland, ME, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 36,094 square feet of properties for sale, with an estimated market value of $10,206,950.

    Sale prices for medical spaces in South Portland, ME start at $925,000, averaging $2,551,737, and reaching up to $4,327,286 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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