Add Listing
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Property Types
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Seneca, SC Retail Space for Sale

    Notify Me
    List
    Map
    Historical Brick Building in Seneca
    $999,949

    Historical Brick Building in Seneca

    235 Main St, Seneca, SC 29678

    Three-level, 15,600 SF building in Seneca's Opportunity Zone.

    • Historical 3‑level brick building.
    • Free‑standing corner location, one block from Ram Cat Alley.
    • Opportunity Zone location.
    • Main level currently used as retail space.
    • Hardwood and concrete flooring throughout.
    Updated: Sep 23, 2025
    View details
    Seneca Retail Building For Sale
    $1,399,999

    Seneca Retail Building For Sale

    12020 North Radio Station Rd, Seneca, SC 29678

    12,000 SF building with conversion potential in Seneca, SC.

    • High potential for conversion into a multi‑tenant strip center with six existing storefronts.
    • Large 12,000 SF building suitable for single‑user or multi‑tenant occupancy.
    • Situated on a sizable 2.42‑acre lot with room for future expansion.
    • Features a fire sprinkler system and three roll‑up doors.
    • Ceiling heights of 20 feet in the front and 16 feet in the rear.
    View details
    Based on your search, we've compiled 188 Potential Opportunities for your consideration. Besides 2 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 182 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Downtown Walhalla Mixed-Use Gem
    $875,000
    16,515 SF

    Downtown Walhalla Mixed-Use Gem

    16,515 SF, Vacant, Redevelopment Opportunity

    222 Main St, Walhalla, SC 29691
    View details
    Historic Retail Buildings on Main
    $1,300,000
    6,130 SF

    Historic Retail Buildings on Main

    Renovated retail spaces with historic charm and modern amenities.

    214-218 E Main St, Walhalla, SC 29691
    View details
    Downtown Westminster Retail/Office Opportunity
    $79,000
    2,500 SF

    Downtown Westminster Retail/Office Opportunity

    Unfinished space in downtown Westminster, suitable for retail or office.

    210 E Main St, Westminster, SC 29693
    View details
    Westminster Commercial Space For Sale
    $135,000
    1,148 SF

    Westminster Commercial Space For Sale

    Versatile commercial space in high-traffic location, ready for customization.

    111 Retreat St, Westminster, SC 29693
    View details

    Explore Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    285 Applewood Center Pl

    285 Applewood Center Pl

    Lifestyle centers • 245,000 SF
    Value Estimation by Request
    285 Applewood Center Pl, Seneca, SC 29678
    View details
    1600 Shiloh Rd

    1600 Shiloh Rd

    RETAIL STORES (PERSONAL SERVICES) • 912 SF
    Value Estimation by Request
    1600 Shiloh Rd, Seneca, SC 29678-4937
    View details
    125 Thrift Ave

    125 Thrift Ave

    RETAIL STORES (PERSONAL SERVICES) • 18,976 SF
    Value Estimation
    $1,765,000
    125 Thrift Ave, Seneca, SC 29678-0915
    View details
    118 Townville St

    118 Townville St

    RETAIL STORES (PERSONAL SERVICES) • 2,548 SF
    Value Estimation by Request
    118 Townville St, Seneca, SC 29678-3226
    View details
    105 Townville St

    105 Townville St

    RETAIL STORES (PERSONAL SERVICES) • 2,160 SF
    Value Estimation by Request
    105 Townville St, Seneca, SC 29678-3225
    View details
    Seneca, SC 29678

    Seneca, SC 29678

    RETAIL STORES (PERSONAL SERVICES) • 7,860 SF
    Value Estimation by Request
    Seneca, SC 29678
    View details
    998 By Pass 123

    998 By Pass 123

    RETAIL STORES (PERSONAL SERVICES) • 3,648 SF
    Value Estimation by Request
    998 By Pass 123, Seneca, SC 29678-4757
    View details
    1097 By Pass 123

    1097 By Pass 123

    RETAIL STORES (PERSONAL SERVICES) • 5,988 SF
    Value Estimation by Request
    1097 By Pass 123, Seneca, SC 29678-4762
    View details
    202 By Pass 123

    202 By Pass 123

    RETAIL STORES (PERSONAL SERVICES) • 2,400 SF
    Value Estimation by Request
    202 By Pass 123, Seneca, SC 29678-0824
    View details
    10898 Clemson Blvd

    10898 Clemson Blvd

    RETAIL STORES (PERSONAL SERVICES) • 480 SF
    Value Estimation by Request
    10898 Clemson Blvd, Seneca, SC 29678-1359
    View details
    10139 Clemson Blvd

    10139 Clemson Blvd

    RETAIL STORES (PERSONAL SERVICES) • 6,472 SF
    Value Estimation
    $590,000
    10139 Clemson Blvd, Seneca, SC 29678-0818
    View details
    504 Wn 1st St

    504 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 11,840 SF
    Value Estimation by Request
    504 Wn 1st St, Seneca, SC 29678-3141
    View details
    528 By Pass 123rd B Ste B

    528 By Pass 123rd B Ste B

    RETAIL STORES (PERSONAL SERVICES) • 1,254 SF
    Value Estimation by Request
    528 By Pass 123rd B Ste B, Seneca, SC 29678-0866
    View details
    109 En 1st St

    109 En 1st St

    RETAIL STORES (PERSONAL SERVICES) • 4,970 SF
    Value Estimation by Request
    109 En 1st St, Seneca, SC 29678-3240
    View details
    101 Wn 1st St

    101 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 903 SF
    Value Estimation by Request
    101 Wn 1st St, Seneca, SC 29678-3247
    View details
    117 En 1st St

    117 En 1st St

    RETAIL STORES (PERSONAL SERVICES) • 4,820 SF
    Value Estimation by Request
    117 En 1st St, Seneca, SC 29678-3240
    View details
    313 Wn 1st St

    313 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 5,400 SF
    Value Estimation by Request
    313 Wn 1st St, Seneca, SC 29678
    View details
    110 Es 1st St

    110 Es 1st St

    RETAIL STORES (PERSONAL SERVICES) • 1,312 SF
    Value Estimation by Request
    110 Es 1st St, Seneca, SC 29678-3448
    View details
    705 Wn 1st St

    705 Wn 1st St

    RETAIL STORES (PERSONAL SERVICES) • 2,880 SF
    Value Estimation by Request
    705 Wn 1st St, Seneca, SC 29678-2526
    View details
    Seneca, SC 29672

    Seneca, SC 29672

    RETAIL STORES (PERSONAL SERVICES) • 2,304 SF
    Value Estimation by Request
    Seneca, SC 29672
    View details
    1103 Friendship Rd

    1103 Friendship Rd

    RETAIL STORES (PERSONAL SERVICES) • 2,250 SF
    Value Estimation by Request
    1103 Friendship Rd, Seneca, SC 29678
    View details
    420 Holders Lndg Rd

    420 Holders Lndg Rd

    RETAIL STORES (PERSONAL SERVICES) • 3,997 SF
    Value Estimation by Request
    420 Holders Lndg Rd, Seneca, SC 29672-0707
    View details

    Seneca, SC Retail Space Investment Opportunities Market Analysis

    Explore 184 retail space for sale in Seneca, SC on our real estate platform. These investment opportunities span a total of 1,241,461 square feet of properties for sale, with an estimated market value of $18,975,000.

    Sale prices for retail space in Seneca, SC start at $50,000, averaging $441,279, and reaching up to $1,650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Browse Retail space for Sale Near Seneca, SC

    Popular Searches in Seneca, SC

    Most Searched ZIP Codes in Seneca, SC

    • 29678
    • 29672

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!