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Seneca, SC Retail Space for Sale

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Historical Brick Building in Seneca
$999,949

Historical Brick Building in Seneca

235 Main St, Seneca, SC 29678

Three-level, 15,600 SF building in Seneca's Opportunity Zone.

  • Historical 3‑level brick building.
  • Free‑standing corner location, one block from Ram Cat Alley.
  • Opportunity Zone location.
  • Main level currently used as retail space.
  • Hardwood and concrete flooring throughout.
Last Update: Sep 23
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Based on your search, we've compiled 187 Potential Opportunities for your consideration. Besides 1 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 182 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Downtown Walhalla Mixed-Use Gem
$875,000
16,515 SF

Downtown Walhalla Mixed-Use Gem

16,515 SF, Vacant, Redevelopment Opportunity
222 Main St, Walhalla, SC 29691
View details
Historic Retail Buildings on Main
$1,300,000
6,130 SF

Historic Retail Buildings on Main

Renovated retail spaces with historic charm and modern amenities.
214-218 E Main St, Walhalla, SC 29691
View details
Westminster Commercial Space For Sale
$145,000
1,148 SF

Westminster Commercial Space For Sale

Versatile commercial space in high-traffic Westminster location.
111 Retreat St, Westminster, SC 29693
View details
Charming Commercial Building on Highway 123
$195,000

Charming Commercial Building on Highway 123

Retail or restaurant opportunity on high-traffic Highway 123 in Westminster.
3518 Toccoa Hwy, Westminster, SC 29693
View details

Explore Off-Market Properties in Seneca, SC

Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

901 North 1St St

901 North 1St St

Individual retail properties • 0.23 Acres
Value Estimation by Request
901 North 1St St, Seneca, SC 29678
View details
605 En 1st St

605 En 1st St

RETAIL STORES (PERSONAL SERVICES) • 3,200 SF
Value Estimation
$140,000
605 En 1st St, Seneca, SC 29678-2823
View details
114 Walnut St

114 Walnut St

RETAIL STORES (PERSONAL SERVICES) • 2,057 SF
Value Estimation
$100,000
114 Walnut St, Seneca, SC 29678-2722
View details
222 En 1st St

222 En 1st St

RETAIL STORES (PERSONAL SERVICES) • 21,940 SF
Value Estimation
$980,000
222 En 1st St, Seneca, SC 29678
View details
403 Main St

403 Main St

RETAIL STORES (PERSONAL SERVICES) • 3,600 SF
Value Estimation by Request
403 Main St, Seneca, SC 29678-2745
View details
926 Friendship Rd

926 Friendship Rd

RETAIL STORES (PERSONAL SERVICES) • 1,984 SF
Value Estimation
$165,000
926 Friendship Rd, Seneca, SC 29678-5342
View details
445 By Pass 123

445 By Pass 123

RETAIL STORES (PERSONAL SERVICES) • 3,400 SF
Value Estimation by Request
445 By Pass 123, Seneca, SC 29678-0842
View details
166 Bilo Pl

166 Bilo Pl

RETAIL STORES (PERSONAL SERVICES) • 11,680 SF
Value Estimation by Request
166 Bilo Pl, Seneca, SC 29678-2563
View details
225 Main St

225 Main St

RETAIL STORES (PERSONAL SERVICES) • 11,158 SF
Value Estimation by Request
225 Main St, Seneca, SC 29678-3245
View details
123 Townville St

123 Townville St

RETAIL STORES (PERSONAL SERVICES) • 8,864 SF
Value Estimation
$890,000
123 Townville St, Seneca, SC 29678-3254
View details
9910 Clemson Blvd

9910 Clemson Blvd

RETAIL STORES (PERSONAL SERVICES) • 2,100 SF
Value Estimation by Request
9910 Clemson Blvd, Seneca, SC 29678-0832
View details
533 By Pass 123

533 By Pass 123

RETAIL STORES (PERSONAL SERVICES) • 7,000 SF
Value Estimation by Request
533 By Pass 123, Seneca, SC 29678-0845
View details
4060 Keowee School Rd

4060 Keowee School Rd

RETAIL STORES (PERSONAL SERVICES) • 2,496 SF
Value Estimation by Request
4060 Keowee School Rd, Seneca, SC 29672-0640
View details
116 Ram Cat Aly

116 Ram Cat Aly

RETAIL STORES (PERSONAL SERVICES) • 5,872 SF
Value Estimation by Request
116 Ram Cat Aly, Seneca, SC 29678-3262
View details
101 Wn 1st St

101 Wn 1st St

RETAIL STORES (PERSONAL SERVICES) • 903 SF
Value Estimation by Request
101 Wn 1st St, Seneca, SC 29678-3247
View details
123 En 1st St

123 En 1st St

RETAIL STORES (PERSONAL SERVICES) • 4,420 SF
Value Estimation by Request
123 En 1st St, Seneca, SC 29678-3240
View details
319 Main St

319 Main St

RETAIL STORES (PERSONAL SERVICES) • 10,400 SF
Value Estimation by Request
319 Main St, Seneca, SC 29678-2743
View details
711 Wn 1st St

711 Wn 1st St

RETAIL STORES (PERSONAL SERVICES) • 1,800 SF
Value Estimation
$110,000
711 Wn 1st St, Seneca, SC 29678-2526
View details
901 Wn 1st St

901 Wn 1st St

RETAIL STORES (PERSONAL SERVICES) • 1,462 SF
Value Estimation
$85,000
901 Wn 1st St, Seneca, SC 29678-2530
View details
Seneca, SC 29678

Seneca, SC 29678

RETAIL STORES (PERSONAL SERVICES) • 8,320 SF
Value Estimation by Request
Seneca, SC 29678
View details
114 Townville St

114 Townville St

RETAIL STORES (PERSONAL SERVICES) • 5,552 SF
Value Estimation
$505,000
114 Townville St, Seneca, SC 29678-3226
View details
640 Old Clemson Hwy

640 Old Clemson Hwy

RETAIL STORES (PERSONAL SERVICES) • 6,000 SF
Value Estimation by Request
640 Old Clemson Hwy, Seneca, SC 29672-7535
View details
150 Keowee Marina Dr

150 Keowee Marina Dr

RETAIL STORES (PERSONAL SERVICES) • 2,139 SF
Value Estimation by Request
150 Keowee Marina Dr, Seneca, SC 29672-4725
View details

Seneca, SC Retail Space Investment Opportunities Market Analysis

Explore 181 retail space for sale in Seneca, SC on our real estate platform. These investment opportunities span a total of 1,241,461 square feet of properties for sale, with an estimated market value of $18,975,000.

Prices for retail space in Seneca, SC start at $50,000, averaging $441,279, and reaching up to $1,650,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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