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    Florence County, SC Retail Space for Sale

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    Prime Retail Investment Opportunity
    $550,000
    2,304 SF

    Prime Retail Investment Opportunity

    225 W Lucas St, Florence, SC 29501

    Two-unit property with high visibility and income potential in Florence.

    • Prime commercial investment opportunity on the high‑traffic US‑52/Lucas Street Corridor (24,700 vehicles daily).
    • Versatile two‑unit property with dual revenue stream potential (convenience/restaurant + potential liquor store).
    • Front unit equipped for restaurant conversion: natural gas, commercial hood vent, take‑out window, seating area.
    • Rear unit has permit application underway for liquor store operations.
    • Located in Florence City Council’s targeted redevelopment zone for the US‑52 Corridor.
    Last Update: Jul 24
    View details
    Prime Commercial Investment Opportunity
    $550,000
    2,304 SF

    Prime Commercial Investment Opportunity

    225 W Lucas St, Florence, SC 29501

    Two-unit property with high visibility and income potential.

    • Prime commercial investment opportunity in a high‑traffic location (24,700 vehicles daily) along the US‑52/Lucas Street Corridor.
    • Versatile two‑unit property with dual revenue stream potential; rear unit has permit application underway for liquor store operations.
    • Front unit (225 W Lucas St) is equipped for restaurant conversion with natural gas access, commercial hood vent, and take‑out window.
    • Located in Florence City Council’s targeted redevelopment zone for the US‑52 Corridor, with planned infrastructure improvements.
    • Outstanding visibility and accessibility, located minutes from I‑95 and surrounded by over 5,000 hotel rooms.
    Last Update: Jul 24
    View details
    Florence, SC Medical Facility
    $4,092,000
    17,174 SF

    Florence, SC Medical Facility

    Corporate-leased medical building, high NOI.
    1933 2Nd Loop Rd, Florence, SC 29501
    View details
    Retail Property in Prime Location
    $1,389,000
    4,160 SF

    Retail Property in Prime Location

    Single-tenant net-leased The Vitamin Shoppe in Florence, SC.
    2590 David H Mcleod Blvd, Florence, SC 29501
    View details
    Based on your search, we've compiled 242 Potential Opportunities for your consideration. Besides 4 Active listings in Florence County, SC, we suggest exploring several alternatives: similar 238 Off-Market properties to explore as potential leads

    Explore Off-Market Properties in Florence County, SC

    Consider similar Off-Market properties in Florence County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    130 Dargan St

    130 Dargan St

    Individual retail properties • 6,520 SF
    Value Estimation by Request
    130 Dargan St, Florence, SC 29506
    View details
    113 Main St

    113 Main St

    Individual retail properties • 7,830 SF
    Value Estimation by Request
    113 Main St, Lake City, SC 29560
    View details
    1933 2Nd Loop Rd

    1933 2Nd Loop Rd

    Individual retail properties • 17,174 SF
    Value Estimation by Request
    1933 2Nd Loop Rd, Florence, SC 29501
    View details
    101 Evans St

    101 Evans St

    RETAIL STORES (PERSONAL SERVICES) • 22,242 SF
    Value Estimation by Request
    101 Evans St, Florence, SC 29501-3425
    View details
    3410 Cummings Rd

    3410 Cummings Rd

    RETAIL STORES (PERSONAL SERVICES) • 10,792 SF
    Value Estimation
    $1,470,000
    3410 Cummings Rd, Timmonsville, SC 29161-7733
    View details
    167 Dargan St

    167 Dargan St

    RETAIL STORES (PERSONAL SERVICES) • 1,722 SF
    Value Estimation by Request
    167 Dargan St, Florence, SC 29506-2501
    View details
    155 Dargan St

    155 Dargan St

    RETAIL STORES (PERSONAL SERVICES) • 3,920 SF
    Value Estimation by Request
    155 Dargan St, Florence, SC 29506-2578
    View details
    1508th N Cashua Dr

    1508th N Cashua Dr

    RETAIL STORES (PERSONAL SERVICES) • 11,000 SF
    Value Estimation by Request
    1508th N Cashua Dr, Florence, SC 29501-6970
    View details
    1359 Irby St

    1359 Irby St

    RETAIL STORES (PERSONAL SERVICES) • 2,080 SF
    Value Estimation by Request
    1359 Irby St, Florence, SC 29505-2757
    View details
    155 Main St

    155 Main St

    RETAIL STORES (PERSONAL SERVICES) • 2,000 SF
    Value Estimation by Request
    155 Main St, Pamplico, SC 29583-9715
    View details
    301 Thomas St

    301 Thomas St

    RETAIL STORES (PERSONAL SERVICES) • 12,261 SF
    Value Estimation by Request
    301 Thomas St, Lake City, SC 29560-3243
    View details
    319 Mercy St

    319 Mercy St

    RETAIL STORES (PERSONAL SERVICES) • 1,200 SF
    Value Estimation by Request
    319 Mercy St, Lake City, SC 29560-2331
    View details
    3376 Palmetto St

    3376 Palmetto St

    RETAIL STORES (PERSONAL SERVICES) • 7,416 SF
    Value Estimation
    $680,000
    3376 Palmetto St, Florence, SC 29501-5942
    View details
    1933 Hoffmeyer Rd

    1933 Hoffmeyer Rd

    RETAIL STORES (PERSONAL SERVICES) • 11,700 SF
    Value Estimation
    $480,000
    1933 Hoffmeyer Rd, Florence, SC 29501-4011
    View details
    631 Irby St

    631 Irby St

    RETAIL STORES (PERSONAL SERVICES) • 1,110 SF
    Value Estimation by Request
    631 Irby St, Florence, SC 29501-5211
    View details
    1551 2nd Loop Rd

    1551 2nd Loop Rd

    RETAIL STORES (PERSONAL SERVICES) • 15,400 SF
    Value Estimation by Request
    1551 2nd Loop Rd, Florence, SC 29505-2803
    View details
    1823 Old Riv Rd

    1823 Old Riv Rd

    RETAIL STORES (PERSONAL SERVICES) • 9,100 SF
    Value Estimation by Request
    1823 Old Riv Rd, Johnsonville, SC 29555-8023
    View details
    1227 Cashua Dr

    1227 Cashua Dr

    RETAIL STORES (PERSONAL SERVICES) • 1,800 SF
    Value Estimation by Request
    1227 Cashua Dr, Florence, SC 29501-6937
    View details
    1901 Palmetto St

    1901 Palmetto St

    RETAIL STORES (PERSONAL SERVICES) • 3,060 SF
    Value Estimation by Request
    1901 Palmetto St, Florence, SC 29501-3916
    View details
    1125 Evans St

    1125 Evans St

    RETAIL STORES (PERSONAL SERVICES) • 23,232 SF
    Value Estimation by Request
    1125 Evans St, Florence, SC 29501-3319
    View details

    Florence County, SC Retail Space Investment Opportunities Market Analysis

    Explore 240 retail space for sale in Florence County, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 5,770,079 square feet of properties for sale, with an estimated market value of $89,137,000.

    Prices for retail space in Florence County, SC start at $55,000, averaging $775,104, and reaching up to $13,230,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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