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    Spartanburg County, SC Office Spaces for Lease

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    Regus Coworking Space with Meeting Rooms
    Regus Coworking Space with Meeting Rooms

    500 W Main St 2nd Floor, Spartanburg, SC 29301

    Contact for pricing

    Regus coworking and private office space on the second floor with fully equipped meeting rooms.

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    Turnkey Office Units
    Turnkey Office Units

    1791 E. Blackstock Rd., Moore, SC 29369

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    Designed for professional, medical, dental, insurance, and administrative operations with limited buildout requirements.

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    Westside Office/Medical Space Available
    Westside Office/Medical Space Available

    225 E Blackstock Rd, Spartanburg, SC

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    5,461 sqft 0.94 AC lot

    5461± sq ft office/medical space for rent.

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    Mixed-Use Building with Outdoor Area
    Mixed-Use Building with Outdoor Area

    500 W Main St, Spartanburg, SC 29301

    Contact for pricing
    10,992 sqft

    Built in 1916 and renovated 2023–2024, featuring retail, restaurant, office, and entertainment space plus large rear outdoor area.

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    Renovated Historic Mixed-Use Building
    Renovated Historic Mixed-Use Building

    500 W Main St, Spartanburg, SC 29301

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    4,388 sqft

    Historic building renovated 2023–2024 with retail, restaurant, office, and entertainment space plus ample parking.

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    Renovated Office Building with Parking
    Renovated Office Building with Parking

    500 W Main St, Spartanburg, SC 29301

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    5,061 sqft

    Office component in a mixed-use building renovated 2023–2024 with ample parking and multiple ingress/egress options.

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    Three-Level Professional Office Building
    Three-Level Professional Office Building

    291 S. Pine Street, Spartanburg, SC 29301

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    Professional office building with three levels, multiple conference rooms, outdoor patio, and on-site parking for 38 vehicles.

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    Spartanburg Office Space For Rent
    Spartanburg Office Space For Rent

    135 West Main Street, Spartanburg, SC

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    1,700 sqft 0.08 AC lot

    Office space available for rent in Spartanburg, SC.

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    Private Office Suites
    Private Office Suites

    7931 Valley Falls Rd, Spartanburg, SC 29303

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    Single-story workspace offers individual offices plus shared reception and conference facilities for a professional client experience.

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    Office Space on Asheville Highway
    Office Space on Asheville Highway

    8891 Asheville Hwy, Boiling Springs, SC

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    1,191 sqft 0.68 AC lot

    Office space for lease with road frontage and ample parking.

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    Multi-Suite Office Building
    Multi-Suite Office Building

    900 S Pine St, Spartanburg, SC 29302

    Contact for pricing
    1,250 sqft

    Second- and first-floor office suites with private bathrooms, natural light, and surface parking.

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    Office Suites in Spartanburg
    Office Suites in Spartanburg

    900 S Pine St, Spartanburg, SC

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    1,218 sqft 0.68 AC lot

    Office suites available in Spartanburg near downtown and amenities.

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    Spartanburg Office Space For Rent
    Spartanburg Office Space For Rent

    2375 E Main St, Spartanburg, SC

    Contact for pricing
    120 sqft 2.28 AC lot

    Office space available for lease in Spartanburg, South Carolina.

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    Retail and Office Space for Lease
    Retail and Office Space for Lease

    2509 Stone Station Rd, Roebuck, SC 29376

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    Retail and office units are available for lease at 2509 Stone Station Rd in Roebuck, South Carolina.

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    Spartanburg Office Space for Lease
    Spartanburg Office Space for Lease

    301 N Pine St, Spartanburg, SC

    Contact for pricing
    1,200 sqft 0.35 AC lot

    Office space available near downtown Spartanburg with on-site parking.

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    Mixed-Use Building in Opportunity Zone
    Mixed-Use Building in Opportunity Zone

    500 W Main St, Spartanburg, SC

    Contact for pricing
    1,683 sqft 7.26 AC lot

    Retail, restaurant, office, and entertainment spaces for lease.

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    Subdividable Two-Story Office Building
    Subdividable Two-Story Office Building

    201 Henry Pl, Spartanburg, SC 29306

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    9,240 sqft 0.68 AC lot

    Two-story office building with approximately 4,600 sq. ft. per level and flexible subdivision into four units.

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    Office Building For Lease
    Office Building For Lease

    3610 Moore Duncan Hwy, Moore, SC 29369

    Contact for pricing
    5,176 sqft

    Standalone office building available for lease, offering approximately 5,176 square feet of dedicated workspace.

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    Class A Office Space
    Class A Office Space

    1460 John B White Sr Blvd, Spartanburg, SC

    Contact for pricing
    2,963 sqft 3.65 AC lot

    Professional office space on Spartanburg's Westside with high visibility.

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    Office Units with New HVAC
    Office Units with New HVAC

    97 Industrial Park Rd, Roebuck, SC 29376

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    Multiple offices include shared meeting, reception, restroom, and breakroom areas.

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    Office Building with Fiber Connectivity
    Office Building with Fiber Connectivity

    310 Inglesby Pkwy, Duncan, SC 29334

    Contact for pricing
    22,000 sqft

    Professional entry areas, rear dock capacity, and an employee patio support daily operations.

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    Office and Retail Space
    Office and Retail Space

    1215 Boiling Springs Road, Spartanburg, SC 29303

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    Mixed office and retail space available on Boiling Springs Road.

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    Office and Retail Flex Space
    Office and Retail Flex Space

    603 W Main St, Spartanburg, SC 29301

    Contact for pricing
    1,700 sqft

    Office/retail space with multiple rooms and open areas, rear parking, and roughly 100 feet of road frontage.

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    Office Building Near Major Interstates
    Office Building Near Major Interstates

    300 Henry Pl, Spartanburg, SC 29306

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    Built in 1990, this office building offers convenient access to I-26 and I-85 for regional connectivity.

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