Onondaga County, NY Office Spaces for Rent & Lease

$5,000/Mo

37,112 SF

Syracuse Office Space Sublease

422 W Onondaga Street, Syracuse, NY 13202

Office space for sublease, all-inclusive rent covers utilities and maintenance.

All‑inclusive $5,000 monthly rate covers rent, utilities, parking, maintenance, and more.
Sublease term extends through October 31, 2029.
Ideal for a wide range of professional or office activities.
Well‑maintained and professionally managed environment.
Includes essential services like snow plowing/removal and groundskeeping.

Updated: Mar 5

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$14 SF/Yr

1,247 SF

Turnkey Commercial Space Available Now

634 Old Liverpool Rd, Liverpool, NY 13088

Versatile 1,200 sq ft space ideal for retail or office.

High‑visibility roadside location on Old Liverpool Road, across from 66 new apartments.
Turnkey commercial space suitable for retail, office, or studio use.
Approximately 1,200 sq ft of flexible, open layout space.
Ample on‑site parking for 8‑10 vehicles.
Large front windows for natural light and signage opportunities.

Updated: May 22

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$19 SF/Yr

5,126 SF

Medical Office Space Available

5,126 SF medical office suite for lease.

792 North Main Street, North Syracuse, NY 13212

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$5,000/Mo

Sublease Office Space Available

Office space for sublease with all-inclusive monthly rate.

422 W Onondaga St, Syracuse, NY 13202

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$22 SF/Yr

4,168 SF

Downtown Syracuse Class A Office

Class A office space in downtown Syracuse for lease.

333 West Washington Street, Syracuse, NY 13202

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$16 SF/Yr

6,556 SF

Pioneer Business Park Office Suite

Build-to-suit office suite in a vibrant business park.

5009 Campuswood Dr, East Syracuse, NY 13057

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$16 SF/Yr

2,029 SF

Professional Office Space Available

2,029 SF office space with highway and university access.

3125 East Genesee Street, Syracuse, NY 13224

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$16 SF/Yr

2,500 SF

Creative Office Space in Syracuse

Modern office space with natural light and flexible floor plans.

200 S Geddes St, Syracuse, NY

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Warehouse/Distribution Space in East Syracuse

$6 SF/Yr

88,540 SF

Warehouse/Distribution Space in East Syracuse

88,540 SF warehouse/distribution space with 10,000 SF office area.

6600 New Venture Gear Drive, East Syracuse, NY 13057

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7,092 SF

Class A Office Suites Available

Modern office suites with ample natural light near major highways.

225 Greenfield Parkway, Liverpool, NY 13088

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$3,376/Mo

5,064 SF

East Syracuse Office Building For Rent

5,064 SF office building with yard and generator.

6331 E Molloy Rd, East Syracuse, NY

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$18 SF/Yr

23,201 SF

Iconic Mixed-Use State Tower

Mixed-use property with office, residential, and retail spaces available.

109 South Warren Street, Syracuse, NY 13202

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$355,000 SF/Yr

Turnkey Medical Office Space Available

Professionally renovated medical office with suites, kitchen, and ample parking.

127-29 Seeley Rd, Syracuse, NY 13224

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$18 SF/Yr

1,100 SF

Office Space Available For Rent

Office space for rent at 709 Erie Blvd W.

709 Erie Blvd W, Syracuse, NY

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$13 SF/Yr

2,600 SF

Syracuse Office Space Available

Office space available for rent in Syracuse, New York.

208 S Warren St, Syracuse, NY

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$12 SF/Yr

2,500 SF

Prime Armory Square Office Space

Commercial office space for lease in the heart of Armory Square.

316 S Clinton St, Syracuse, NY

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15,000 SF

Downtown Syracuse Office Building

15,163 SF office building in downtown Syracuse for lease.

716 James Street, Syracuse, NY 13203

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$20 SF/Yr

7,054 SF

Class A Office Space Available

Prestigious office building in historic Franklin Square, Syracuse.

500 Plum Street, Syracuse, NY 13204

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6,300 SF

Renovated Office Building with Parking

Downtown office building with on-site parking and renovated interior.

506 E Washington St, Syracuse, NY 13202

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$18 SF/Yr

15,000 SF

Restored Office Building in Syracuse

Restored office building with parking near Armory Square.

358 W Jefferson St, Syracuse, NY

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1,572 SF

Commissary Kitchen on Collamer Road

1,572 SF fully-built commissary kitchen with frontage.

6491 Collamer Rd, East Syracuse, NY 13057

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$16 SF/Yr

1,295 SF

Syracuse Office Space Available

Office space available for lease in Syracuse, New York.

451 S Main St, Syracuse, NY

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$16 SF/Yr

2,500 SF

Cicero Medical & Office Spaces

Medical and office spaces for lease in Cicero, NY.

6221 Rte 31, Cicero, NY

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Downtown Syracuse Office Space Available

$17 SF/Yr

4,039 SF

Downtown Syracuse Office Space Available

4,039 SF office space with city views.

100-120 Madison St, Syracuse, NY

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Onondaga County, NY Office Spaces Leasing Opportunities Market Analysis

Explore Office Spaces leasing options in Onondaga County, NY with 103 listings featured on our commercial real estate exchange. The current inventory includes 543,527 square feet of properties with an estimated lease value of $828 /Mo.

Estimated lease rates for Office Spaces in Onondaga County, NY begin at $1.57 SF/Yr, with an average of $19 SF/Yr and extend to $180 SF/Yr.