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Dewitt, NY Office Spaces for Lease

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88 properties
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Second-Floor Office Suite with Roof Access
Updated: Jul 25
Second-Floor Office Suite with Roof Access

308 W Genesee Street, Syracuse, NY 13202

$10,000/Mo
11,220 sqft 0.42 AC lot
Second‑floor office suite in shell condition requiring full build‑out
Stairwell provides roof access for outdoor space
Large windows and forced‑air heating
Zoned MX‑5
11,220 SF on a 0.4183‑acre lot
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Retail Space with Central Air
Updated: Aug 10
Retail Space with Central Air

4455A E Genesee Street, Syracuse, NY 13214

$1,300/Mo
14,760 sqft 0.86 AC lot
14,760‑square‑foot retail property on a 0.86‑acre parcel
Multiple listed use options, including retail, office, service, gallery, studio, and take‑out food service
Central air conditioning and natural gas forced‑air heating
Public water and public sewer
Built in 1963 with a flat roof
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Office Unit with Included Services
Office Unit with Included Services

422 W Onondaga Street, Syracuse, NY 13202

$5,000/Mo
37,112 sqft 0.91 AC lot

Office sublease with utilities, parking, and property maintenance included.

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Creative Space With Roof Access
Creative Space With Roof Access

308 W Genesee St, Syracuse, NY 13202

$10,000/Mo
11,220 sqft

Second-floor shell space offers large windows, flexible build-out potential, and access to a rooftop outdoor area.

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Renovated Live-Work Space
Renovated Live-Work Space

480 S Salina Street, Syracuse, NY 13202

$1,850/Mo

Two-story unit combines residential areas with a substantial office area and includes in-unit laundry.

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Mixed-Use Building with Diner
Mixed-Use Building with Diner

3604 Court Street, Syracuse, NY 13206

Contact for pricing
5,351 sqft 0.41 AC lot

Includes a mechanic garage and one-bedroom apartment under the same roof.

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Furnished Office Units with Parking
Furnished Office Units with Parking

580 South Salina Street, Syracuse, NY 13202

$11.67-$14 SF/Yr
3,600 sqft

CBD-zoned office premises with optional furniture, basement storage, and exterior signage opportunities.

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Medical Office Space Available
Medical Office Space Available

792 North Main Street, North Syracuse, NY 13212

$18.50 SF/Yr
5,126 sqft

5,126 SF medical office suite for lease.

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Downtown Syracuse Class A Office
Downtown Syracuse Class A Office

333 West Washington Street, Syracuse, NY 13202

$22 SF/Yr
3,041 sqft

Class A office space in downtown Syracuse for lease.

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Corner Office Unit
Corner Office Unit

447 E Washington St, Syracuse, NY 13202

$3,000/Mo

Ground-level commercial space combines an adaptable open area with separate private and public restrooms.

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Iconic Mixed-Use State Tower
Iconic Mixed-Use State Tower

109 South Warren Street, Syracuse, NY 13202

$18.50 SF/Yr
23,201 sqft

Mixed-use property with office, residential, and retail spaces available.

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Office Unit in Office Building
Office Unit in Office Building

580-584 South Salina Street, Syracuse, NY 13202

Contact for pricing
3,600 sqft

Office floor near downtown transit, a regional STEAM school, and Salt City market.

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Creative Office/Retail Space
Creative Office/Retail Space

112 Wilkinson St, Syracuse, NY 13204

Contact for pricing
12,500 sqft

Second-floor creative office and retail space offers natural light and a flexible blank-canvas layout.

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Medical-Convertible Office Suite
Medical-Convertible Office Suite

6567 Kinne Rd, Syracuse, NY 13214

Contact for pricing
8,400 sqft

Office space with multiple offices, conference rooms, and private bathrooms, supported by shared-building water for possible medical use.

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Flex Warehouse with Office
Flex Warehouse with Office

209 Factory Ave, Syracuse, NY 13208

Contact for pricing
6,615 sqft 0.27 AC lot

Flex facility includes 3,200 SF of Class A office space and 3,415 SF warehouse with two automatic overhead doors.

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Flex Space with Loading Docks
Flex Space with Loading Docks

530 State Fair Blvd, Syracuse, NY 13204

Contact for pricing
15,000 sqft

Adaptable flex space with office area, three-phase power, dock access, and sprinkler protection.

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Office Suite with Large Window Lines
Office Suite with Large Window Lines

2804-2806 Court St, Syracuse, NY 13208

Contact for pricing
1,225 sqft

First-floor office space for lease with strong natural light and window lines in a two-floor layout.

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Second-Floor Office Suite
Second-Floor Office Suite

550 Westcott Street, Syracuse, NY 13210

Contact for pricing
1,300 sqft

Bright second-floor suite with front and rear windows, flexible layout, luxury vinyl flooring, and freshly painted interiors.

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Divisible Office Units
Divisible Office Units

5982 East Molloy Road, Syracuse, NY 13211

Contact for pricing
3,000 sqft

Office building with a flexible layout that can support separate tenant spaces and access to an additional rear lot.

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Medical Office Suite with Exam Rooms
Medical Office Suite with Exam Rooms

3400 Vickery Rd, Syracuse, NY 13212

Contact for pricing
4,196 sqft

Suite C offers a mix of open space, private offices, and exam rooms for healthcare use.

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Class A Office Park Space
Class A Office Park Space

301 Plainfield Road, Syracuse, NY

$18 SF/Yr
96,084 sqft

Class A office space available in Syracuse, New York.

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Syracuse Flex Space For Rent
Syracuse Flex Space For Rent

4601 Nixon Park Drive, Syracuse, NY

$5.25 SF/Yr
62,000 sqft

Flex/industrial/office space near Route 175, Syracuse, NY.

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Class A Suburban Office Park
Class A Suburban Office Park

200 Salina Meadows Pkwy, Syracuse, NY

$18 SF/Yr
44,730 sqft

Class A office space for rent in Syracuse, New York.

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Class A Suburban Office Park
Class A Suburban Office Park

220 Salina Meadows Pkwy, Syracuse, NY

$18 SF/Yr
44,730 sqft

Class A office space for rent in Syracuse, New York.

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Dewitt, NY Office Spaces Lease Rates & Market Statistics

Explore 88 Office Spaces for lease in Dewitt, NY on Realmo, a commercial real estate exchange covering the Dewitt area. The current inventory totals 1,474,360 square feet of properties — an average of ~16,750 SF per listing.

Office Spaces lease rates in Dewitt range from $1.06 SF/Yr at the entry level to $22 SF/Yr at the top of the market, averaging $13.76 SF/Yr. That's a 21x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $13.76 SF/Yr, the local average runs 58% below New York's state average of $32.55 SF/Yr.

Dewitt accounts for 60% of the 147 office spaces currently available across Onondaga County, where nearby markets include Syracuse and Liverpool. By space type, the market includes 65 office units, 21 office buildings and 10 medical office space listings — office units typically offer the lowest entry point, while office buildings command the highest rates.

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