Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    East Syracuse, NY Office Properties & Spaces for Lease

    List
    Map
    New York, NY Brooklyn, NY Queens, NY
    19 results
    East Syracuse Commercial Space Available
    $1,900 /Mo
    14,506 SF

    East Syracuse Commercial Space Available

    5710 Commons Park, East Syracuse, NY 13057

    Class A office space in desirable East Syracuse location.

    • Highly desirable location near Widewaters Parkway with easy access to major highways and downtown Syracuse.
    • Gross lease: Landlord pays for heat, air conditioning, and electricity.
    • Impeccably maintained Class A professional building with newly remodeled kitchen and recently painted exterior.
    • Excellent accessibility: One‑story building with no stairs and plenty of free parking.
    • Access to shared restrooms, conference room, and outdoor patio.
    Updated: Dec 30, 2025
    View details
    Pioneer Business Park Office Suite
    $16 SF/Yr
    6,556 SF

    Pioneer Business Park Office Suite

    5009 Campuswood Dr, East Syracuse, NY 13057

    Build-to-suit office suite in a vibrant business park.

    • Build‑to‑suit suite allows customization of workspace.
    • Located in the highly desirable Pioneer Business Park.
    • Features two newly renovated bathrooms.
    • Offers direct views of park's ponds and abundant natural light.
    • Access to Pioneer Business Park amenities including hotels, outdoor patios, picnic areas, and a fitness trail.
    Updated: Nov 21, 2025
    View details
    East Syracuse Office Building For Rent
    $4,220 /Mo
    5,064 SF

    East Syracuse Office Building For Rent

    5,064 SF office building with yard and generator.

    6331 E Molloy Rd, East Syracuse, NY
    View details
    Office Suite in Quiet Office Park
    Contact for pricing

    Office Suite in Quiet Office Park

    Office suite with private offices, open space, and conference rooms.

    5852 Heritage Landing Drive, East Syracuse, NY 13057
    View details
    Commissary Kitchen on Collamer Road
    Contact for pricing
    1,572 SF

    Commissary Kitchen on Collamer Road

    1,572 SF fully-built commissary kitchen with frontage.

    6491 Collamer Rd, East Syracuse, NY 13057
    View details
    Office and Flex Suites Available
    $12 SF/Yr
    1,283 SF

    Office and Flex Suites Available

    Office and flex suites with drive-in door options available.

    6437 Collamer Rd, E Syracuse, NY
    View details
    Office/Medical Building To Be Constructed
    Contact for pricing
    7,000 SF

    Office/Medical Building To Be Constructed

    7,000 SF office/medical building, construction starting Spring 2025.

    812 Franklin Park Dr, East Syracuse, NY
    View details
    Office/Medical Building, Spring 2025
    Contact for pricing
    7,000 SF

    Office/Medical Building, Spring 2025

    7,000 SF office/medical building to be constructed Spring 2025.

    820 Franklin Park Dr, East Syracuse, NY
    View details
    E Syracuse Office Space Available
    Contact for pricing
    1,500 SF

    E Syracuse Office Space Available

    25,000 SF building with diverse tenant mix.

    101 Adler Dr, E Syracuse, NY
    View details
    Office/Warehouse Space Available
    Contact for pricing
    6,365 SF

    Office/Warehouse Space Available

    Office and warehouse space with dock and drive-in door.

    7020 Fly Rd, East Syracuse, NY
    View details
    Collamer Office Building Space Available
    Contact for pricing
    1,175 SF

    Collamer Office Building Space Available

    Office spaces for rent in a well-maintained building.

    6670 Old Collamer Rd, E Syracuse, NY
    View details
    Furnished Office Space Available
    Contact for pricing
    1,895 SF

    Furnished Office Space Available

    Move-in ready office space with flexible lease terms.

    5000 Campuswood Dr, East Syracuse, NY
    View details
    New Development Opportunity in Syracuse
    Contact for pricing
    26,000 SF

    New Development Opportunity in Syracuse

    New Class A medical/office or office/warehouse facility for lease.

    6731 Fly Rd, East Syracuse, NY
    View details
    Renovated Retail and Office Space
    Contact for pricing
    17,310 SF

    Renovated Retail and Office Space

    Newly renovated retail and office spaces available for lease.

    7027-7041 Manlius Center Rd, E Syracuse, NY
    View details
    Two-Story Office Building For Rent
    Contact for pricing
    675 SF

    Two-Story Office Building For Rent

    Two-story office building with suites ranging from 440-4,650 square feet.

    6320 Fly Rd, E Syracuse, NY
    View details
    Kirkville Road Medical/Office Suites
    Contact for pricing
    710 SF

    Kirkville Road Medical/Office Suites

    Medical/office suites for lease near I-481 in East Syracuse.

    6700 Kirkville Rd, E Syracuse, NY
    View details
    Class B Office Building
    Contact for pricing
    1,660 SF

    Class B Office Building

    12,000 SF office building near Interstate 481.

    6315 Fly Rd, E Syracuse, NY
    View details
    Divisible Office Building with Garage
    Contact for pricing
    2,870 SF

    Divisible Office Building with Garage

    16,500 SF office building divisible into 2,000+ SF suites.

    1 Adler Dr, E Syracuse, NY
    View details
    Medical Office Near Route 481
    $25 SF/Yr

    Medical Office Near Route 481

    Medical office space with convenient access and ample parking.

    4939 Brittonfield Pkwy, East Syracuse, NY 13057
    View details
    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 19 Active listings in East Syracuse, NY, we suggest exploring alternatives. Similar 5 Properties for Sales.

    Explore Similar Spaces for Sale in East Syracuse, NY

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Modern Class A Office Building
    $4,500,000
    40,625 SF

    Modern Class A Office Building

    40,625 SF office building ideal for medical or conventional use.

    5062 Brittonfield Pkwy, East Syracuse, NY
    View details
    Class A Office Building
    $13,000,000
    45,450 SF

    Class A Office Building

    Net leased office building with bank branch and lower level.

    6611 Manlius Center Road, East Syracuse, NY 13057
    View details
    Manufacturing Warehouse with Office Space
    $2,920,000
    30,000 SF

    Manufacturing Warehouse with Office Space

    30,000 SF manufacturing/warehouse with 8,000 SF office space.

    6250 E Molloy Rd, East Syracuse, NY
    View details
    Class A Office Building
    Contact for pricing
    25,000 SF

    Class A Office Building

    25,000 SF Class A office building in growing area.

    34 Aspen Park Blvd, East Syracuse, NY
    View details
    Former Restaurant Site in Syracuse
    $295,000
    2,373 SF

    Former Restaurant Site in Syracuse

    East Syracuse location ideal for restaurant, office, or retail.

    6596 Old Collamer Rd, East Syracuse, NY 13057
    View details

    East Syracuse, NY Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in East Syracuse, NY with 19 listings featured on our commercial real estate exchange. The current inventory includes 852,469,200 square feet of properties with an estimated lease value of $11 SF/Yr.

    Estimated lease rates for Office properties & Spaces in East Syracuse, NY begin at $1.57 SF/Yr, with an average of $5 SF/Yr and extend to $10 SF/Yr.
    List
    Map

    Browse Office properties & Spaces for Lease Near East Syracuse, NY

    Popular Searches in East Syracuse, NY

    Popular Categories

    Most Searched ZIP Codes in East Syracuse, NY

    • 13057

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!