Fayetteville, NY Office Spaces for Rent & Lease

Updated: Nov 22, 2025

Medical Office Suites For Lease

4000 Medical Center Drive, Fayetteville, NY 13066

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12,228 sqft

Located within Northeast Medical Center.
Affiliated with St. Joseph‘s Health Hospital and SUNY Upstate Medical University.
Current tenants include Laboratory Alliance of Central New York, Dermatology Associates of CNY, Associates for Women‘s Medicine, and Asthma & Allergy Associates P.C.
Medical office suites available for lease.
Located in the eastern suburbs of Syracuse.

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Updated: Nov 24, 2025

Fayetteville Office Space Available

4100 Medical Center Dr, Fayetteville, NY

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2,766 sqft 21.64 AC lot

Large common conference/event room with great views
Ample free outdoor parking
24‑hour access
Loading dock and freight elevator for deliveries
Food/coffee vendor in the lobby

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Fully Furnished Office Units with Conference Room

6832 E Genesee St, Fayetteville, NY 13066

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2,456 sqft

Fully furnished office space with dual-zone HVAC, fob access controls, and a shared conference room.

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 3 Active listings in Fayetteville, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 3 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Retail Space with Central Air

4455A E Genesee Street, Syracuse, NY 13214

$1,300/Mo

14,760 sqft 0.86 AC lot

Commercial space accommodates retail, service, office, gallery, studio, and take-out food operations.

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Class A Office Suite

5710 Commons Park, East Syracuse, NY 13057

$1,850/Mo

950 sqft 2.04 AC lot

One-story professional suite with shared amenities, central air, and convenient access to parking and nearby highways.

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Class A Office Building Suite

5794 Widewaters Pkwy, Syracuse, NY 13214

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19,707 sqft

Class A office building offers ample on-site parking and approximately 20,000 SF available in Widewaters Office Park.

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Office Suite in Quiet Office Park

5852 Heritage Landing Drive, East Syracuse, NY 13057

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Office suite with private offices, open space, and conference rooms.

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Similar Spaces for Sale in Fayetteville, NY

Consider Similar Space for Sale. We found 3 Spaces matching your search parameters.

Historic Three-Story Mixed-Use Building

100 Brooklea Dr, Fayetteville, NY 13066

$1,400,000

10,295 sqft

Fully leased historic property combines storefront, office, and apartment space within Fayetteville’s business district.

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Mixed-Use Property with Fenced Yard

102 W Elm St, Fayetteville, NY 13066

$199,900

1,710 sqft

Two-level configuration combines workspace areas with private residential rooms and outdoor space.

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Former Accounting Office Building

551 E Genesee St, Fayetteville, NY 13066

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4,298 sqft

Office building with ADA ramp access and visibility on a roadway averaging 7,996 vehicles daily.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Commercial Land with Existing Building

8860 Brewerton Road, Brewerton, NY 13029

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239,580 sqft 5.50 AC lot

Commercial land offering an existing building, public utilities, and frontage along two roads.

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Fayetteville, NY Office Spaces Lease Rates & Market Statistics

Explore 3 Office Spaces for lease in Fayetteville, NY on Realmo, a commercial real estate exchange covering the Fayetteville area. The current inventory totals 17,450 square feet of properties.

Fayetteville accounts for 3% of the 101 office spaces currently available across Onondaga County, where nearby markets include Syracuse and Liverpool.