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    De Soto, MO Office Spaces for Lease

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    Bonne Terre, MO Park Hills, MO Festus, MO Leadington, MO Hillsboro, MO Crystal City, MO Farmington, MO Herculaneum, MO
    Office Space with Road Visibility
    Updated: Jun 25, 2025
    Office Space with Road Visibility

    2100 Rock Rd, De Soto, MO 63020

    Contact for pricing
    816 sqft
    Office space for lease with full access along Rock Road
    Strong passing traffic with Rock Road at 6,191 VPD
    High traffic count on Highway 21 at 13,100 VPD
    Office space available
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    Office Space with High Visibility
    Updated: Jun 25, 2025
    Office Space with High Visibility

    2100 Rock Rd, De Soto, MO 63020

    Contact for pricing
    288 sqft
    Office space available
    Full access along Rock Road
    Rock Road traffic count: 6,191 VPD
    Highway 21 traffic count: 13,100 VPD
    View details
    Based on your search, we've compiled 8 Potential Opportunities for your consideration. Besides 2 Active listings in De Soto, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Renovated Office Units
    Renovated Office Units

    1320 YMCA Drive, Festus, MO 63028

    Contact for pricing
    10,600 sqft 2.07 AC lot

    Flexible office workspace with updated building systems, ample parking, and convenient access to nearby restaurants and amenities.

    View details
    Freestanding Office Building
    Freestanding Office Building

    10639 Business 21, Hillsboro, MO 63050

    $2,300/Mo

    Several offices, a kitchen and a restroom create a practical layout for commercial operations.

    View details
    Updated Office Suite
    Updated Office Suite

    130 Main Street, Festus, MO 63028

    $1,795/Mo
    0.14 AC lot

    Single-level commercial suite with private offices, reception space, a kitchen, restroom, and accessible entry.

    View details
    Freestanding Office Building
    Freestanding Office Building

    10639 Business 21, Hillsboro, MO 63050

    $2,300/Mo
    0.61 AC lot

    Flexible office layout with a kitchen, break area, and convenient access along Business 21.

    View details

    Similar Spaces for Sale in De Soto, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Medical Office Building
    Medical Office Building

    126 S Main St, De Soto, MO 63020

    $325,000
    0.14 AC lot

    The interior combines private work areas with a large open room, lab space, and two commercial restrooms.

    View details
    Medical Office with Flexible Layout
    Medical Office with Flexible Layout

    126 S Main St, De Soto, MO 63020

    $325,000

    The interior combines reception and waiting areas with a large open room and space for as many as eight offices.

    View details

    De Soto, MO Office Spaces Lease Rates & Market Statistics

    Browse 2 Office Spaces for lease in De Soto, MO on Realmo, a commercial real estate marketplace serving the De Soto area. The current inventory totals 1,104 square feet of properties.

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    • 63020

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    Realmo connects you with licensed De Soto CRE brokers providing property specifications, local market pricing, and commercial transaction underwriting support.

    Heartland Realty
    50 Jefferson Square Valles Mines, MO 63020
    Phone: (636) 337-0600
    www.heartlandhomesrealty.com
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