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De Soto, MO Office Properties & Spaces for Lease

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Retail and Office Space Available
$2,025/Mo

Retail and Office Space Available

2100 - 2128 Rock Road, De Soto, MO 63020

Retail and office spaces for rent in De Soto.

  • High median household income of $79,438 in one area, reflecting a prosperous community.
  • Significant population base of 46,968 in one area, indicating a vibrant community.
  • Moderate population base of 17,979 in one area.
  • Smaller population base of 10,757 in one area.
  • Moderate daytime population of 8,896 in one area.
Updated: Apr 3
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Retail/Office Space on Rock Road
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288 SF

Retail/Office Space on Rock Road

2100 Rock Rd, De Soto, MO

Retail and office spaces with high visibility and full access.

  • High traffic volume on Highway 21 (13,100 VPD)
  • Full access along Rock Road
  • Great visibility
  • Office space available
  • Traffic volume on Rock Road (6,191 VPD)
Updated: Jun 25, 2025
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Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 2 Active listings in De Soto, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

Explore Office properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Office Building in Festus
$18 SF/Yr
10,600 SF

Renovated Office Building in Festus

Modern, renovated office building with ample parking and convenient location.

Festus, MO 63028
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Festus Retail, Office, Medical Space
Contact for pricing
2,250 SF

Festus Retail, Office, Medical Space

Two spaces available in well-maintained Festus center.

101-109 Borga Bldg, Festus, MO
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Renovated Office/Retail Space Available
Contact for pricing
650 SF

Renovated Office/Retail Space Available

Move-in ready office/retail space with private bath and HVAC.

7204 Executive Pkwy, House Springs, MO 63051
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Former Medical Space Endcap
Contact for pricing
3,600 SF

Former Medical Space Endcap

3,600 SF endcap space suitable for retail or medical use.

21 Walters Pl, House Springs, MO 63051
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Cleared Lot in St Clair
$1.00 SF/Yr

Cleared Lot in St Clair

1.5-acre cleared lot zoned for general commercial use.

Saint Clair, MO 63077
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Collinsville Commercial Space For Lease
$5,000/Mo
5,000 SF

Collinsville Commercial Space For Lease

Versatile commercial space in Collinsville, available immediately.

1902 Vandalia Street, Collinsville, IL 62234
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High-Traffic Commercial Land in Rolla
$7,500/Mo

High-Traffic Commercial Land in Rolla

0.61 acre commercial land in high-traffic area for lease.

704 N Bishop Avenue, Rolla, MO 65401
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Commercial Land on Kingshighway
$5,500/Mo
4,000 SF

Commercial Land on Kingshighway

Prime commercial land for lease in high-traffic Rolla location.

1014 Kingshighway Street, Rolla, MO 65401
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De Soto, MO Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in De Soto, MO with 2 listings featured on our commercial real estate exchange. The current inventory includes 35,544,960 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Office properties & Spaces in De Soto, MO begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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