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    De Soto, MO
    Commercial

    De Soto, MO Commercial Land for Sale

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    Bonne Terre, MO French Village, MO Blackwell, MO Joplin, MO Festus, MO Cadet, MO Desloge, MO Fredericktown, MO
    Commercial-Residential Land Parcel
    Updated: Sep 29, 2025
    Commercial-Residential Land Parcel

    4155 US Highway 67, De Soto, MO 63020

    $599,900
    1,178,733 sqft 27.00 AC lot
    27‑acre commercial/residential land tract with approximately 0.5‑mile frontage on Highway 67
    Includes approximately 0.25‑mile frontage on Flucom Road
    Zoned for both use types: 21 acres commercial and 6 acres residential
    Seller is willing to divide the property
    Marketable timber on the property
    View details
    Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 1 Active listings in De Soto, MO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 24 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Highway-Frontage Commercial Land
    Highway-Frontage Commercial Land

    2533 Highway 67, Festus, MO 63028

    $345,000
    137,214 sqft

    Level commercial site near a signalized intersection with highway access and prominent roadside exposure.

    View details
    Commercial Corner Development Site
    Commercial Corner Development Site

    902 Peach Tree Plaza Dr, Hillsboro, MO 63050

    Contact for pricing
    1 sqft

    C2-zoned development land at Peach Tree Plaza with all utilities to the site and 11,618 combined vehicles daily.

    View details
    Corner Commercial Land
    Corner Commercial Land

    10865 Business 21, Hillsboro, MO 63050

    $350,000
    0.98 AC lot

    Commercial-zoned corner parcel near highways and a busy intersection.

    View details
    Commercial Land with Highway Frontage
    Commercial Land with Highway Frontage

    11730 Cloverleaf Dr, Festus, MO 63028

    Contact for pricing
    6.80 AC lot

    6.8± acres in the city limits with substantial outer-road frontage and prominent Highway 67 visibility.

    View details

    Off-Market Properties in De Soto, MO

    Consider similar Off-Market properties in De Soto, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $270,000
    Estimated value
    0.22 AC lot
    View details
    124 Main St
    VACANT COMMERCIAL LAND

    124 Main St, De Soto, MO 63020-1709

    $270,000
    Estimated value
    0.01 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $265,000
    Estimated value
    1.67 AC lot
    View details
    13036 State Rte 21
    VACANT COMMERCIAL LAND

    13036 State Rte 21, De Soto, MO 63020-1088

    $290,000
    Estimated value
    4.00 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    Value Estimation by Request
    0.19 AC lot
    View details
    301 Clement St
    VACANT COMMERCIAL LAND

    301 Clement St, De Soto, MO 63020

    Value Estimation by Request
    1.70 AC lot
    View details
    608 Main St
    VACANT COMMERCIAL LAND

    608 Main St, De Soto, MO 63020-2206

    $280,000
    Estimated value
    0.14 AC lot
    View details
    1 Clement St
    VACANT COMMERCIAL LAND

    1 Clement St, De Soto, MO 63020

    $2,690,000
    Estimated value
    26,880 sqft 0.57 AC lot
    View details
    512 Main St
    VACANT COMMERCIAL LAND

    512 Main St, De Soto, MO 63020-2204

    $605,000
    Estimated value
    9,945 sqft 0.14 AC lot
    View details
    4572 State Rte 110
    VACANT COMMERCIAL LAND

    4572 State Rte 110, De Soto, MO 63020-3217

    Value Estimation by Request
    4.40 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $275,000
    Estimated value
    0.52 AC lot
    View details
    3623 Athena School Rd
    VACANT COMMERCIAL LAND

    3623 Athena School Rd, De Soto, MO 63020-4591

    $275,000
    Estimated value
    0.99 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $280,000
    Estimated value
    1.07 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $260,000
    Estimated value
    0.36 AC lot
    View details
    4579 Cajun Dr
    VACANT COMMERCIAL LAND

    4579 Cajun Dr, De Soto, MO 63020

    $250,000
    Estimated value
    933 sqft 8.76 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $285,000
    Estimated value
    0.83 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $270,000
    Estimated value
    0.07 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $275,000
    Estimated value
    3.10 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $275,000
    Estimated value
    0.16 AC lot
    View details
    3100 Oak Fence Dr
    VACANT COMMERCIAL LAND

    3100 Oak Fence Dr, De Soto, MO 63020

    $410,000
    Estimated value
    113.25 AC lot
    View details
    115 Fletcher St
    VACANT COMMERCIAL LAND

    115 Fletcher St, De Soto, MO 63020

    $270,000
    Estimated value
    0.36 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $260,000
    Estimated value
    0.55 AC lot
    View details
    De Soto, MO 63020
    VACANT COMMERCIAL LAND

    De Soto, MO 63020

    $270,000
    Estimated value
    0.03 AC lot
    View details

    De Soto, MO Commercial Land Market Trends and Statistics

    Explore 25 commercial land for sale in De Soto, MO on our real estate platform. These investment opportunities span a total of 1,176,120 square feet of properties for sale, with an estimated market value of $599,900.

    Sale prices for commercial lots in De Soto, MO average $599,900 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Residential land & home lots 30
    Recreation land 11
    Waterfront Land 9
    Hunting land 5
    Agricultural land / Farmland 3

    Demographics Overview

    Population 20K
    Population Growth (5Y) +1.8%
    Median Household Income $65,908
    College Educated 18.9%

    High-Yield Neighborhoods for Investment

    Identify De Soto submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    63020 $200K

    Taxes & Financing

    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in St. Francois County

    New Delisted

    Total CRE Inventory on Market (SF)

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