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    De Soto, MO
    Retail

    De Soto, MO Retail Properties & Spaces for Lease

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    Desloge, MO Park Hills, MO Festus, MO Leadington, MO Hillsboro, MO Potosi, MO Crystal City, MO Farmington, MO
    Open-Plan Storefront Space
    Updated: Aug 10
    Open-Plan Storefront Space

    200 S Main Street, De Soto, MO 63020

    $2,695/Mo
    0.14 AC lot
    Approximately 3,000+/- SF of commercial space
    Expansive storefront window line along Main Street
    Open interior layout with 3 half bathrooms
    Triple Net (NNN) lease structure
    Brick building constructed in 1910
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    Retail Space in Downtown DeSoto
    Updated: Jun 24, 2025
    Retail Space in Downtown DeSoto

    De Soto, MO

    Contact for pricing
    5,000 sqft 3.31 AC lot
    Convenient downtown location
    Great visibility
    Roll up doors on end cap
    North Main Street location
    High traffic volume (6,973 VPD)
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    End Cap Strip Mall Space with Roll-Up Doors
    End Cap Strip Mall Space with Roll-Up Doors

    De Soto, MO 63020

    Contact for pricing
    646 sqft

    Downtown end cap strip mall space with roll-up doors on high-traffic North Main Street.

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    Office Space with High Visibility
    Office Space with High Visibility

    2100 Rock Rd, De Soto, MO 63020

    Contact for pricing
    288 sqft

    Office space with full access along Rock Road and strong passing traffic from Rock Road and Highway 21.

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    Retail Space with High-Traffic Frontage
    Retail Space with High-Traffic Frontage

    2100 Rock Rd, De Soto, MO 63020

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    1,550 sqft

    Retail space with full access along Rock Road and strong traffic exposure from Rock Road and Highway 21.

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    Based on your search, we've compiled 13 Potential Opportunities for your consideration. Besides 5 Active listings in De Soto, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

    Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Updated Office Suite
    Updated Office Suite

    130 Main Street, Festus, MO 63028

    $1,795/Mo
    0.14 AC lot

    Single-level commercial suite with private offices, reception space, a kitchen, restroom, and accessible entry.

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    Shopping Center Retail Space
    Shopping Center Retail Space

    110-155 Twin City Mall, Crystal City, MO 63019

    Contact for pricing
    1,200 sqft

    Retail space within a regional shopping center anchored by national and established commercial tenants.

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    Regional Shopping Center Space Available
    Regional Shopping Center Space Available

    110-155 Twin City Mall, Crystal City, MO

    Contact for pricing
    5,115 sqft 12.74 AC lot

    Retail space available in regional shopping center with high visibility.

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    Festus Retail, Office, Medical Space
    Festus Retail, Office, Medical Space

    101-109 Borga Bldg, Festus, MO

    Contact for pricing
    2,250 sqft 9.15 AC lot

    Two spaces available in well-maintained Festus center.

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    Similar Spaces for Sale in De Soto, MO

    Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

    Historic Brick Storefront Building
    Historic Brick Storefront Building

    400 S Main Street, De Soto, MO 63020

    $850,000
    0.14 AC lot

    Two storefront entrances create flexibility for operating one side and leasing the other.

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    Dollar General NNN Retail Property
    Dollar General NNN Retail Property

    1655 Veterans Dr, De Soto, MO 63020

    Contact for pricing
    9,002 sqft

    Recently opened store with corporate backing and an absolute NNN lease structure.

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    Retail Building
    Retail Building

    12939 State Highway 21, De Soto, MO 63020

    Contact for pricing
    60,000 sqft

    Retail property offered for sale totaling 60,000 SF.

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    Retail Space on Main Street
    Retail Space on Main Street

    400 - 420 North Main Street, De Soto, MO 63020

    Contact for pricing

    Retail space available for lease on North Main Street.

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    De Soto, MO Retail properties & Spaces Lease Rates & Market Statistics

    Browse 5 Retail properties & Spaces for lease in De Soto, MO on Realmo, a commercial real estate marketplace serving the De Soto area. The current inventory totals 7,484 square feet of properties.

    Retail properties & Spaces lease rates in De Soto range from $2,695/Mo at the entry level to $2,695/Mo at the top of the market, averaging $2,695/Mo. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings.

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