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    De Soto, MO Retail Properties & Spaces for Lease

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    Saint Louis, MO Louis, MO Kansas City, MO
    Retail/Office Space on Rock Road
    Contact for pricing
    288 SF

    Retail/Office Space on Rock Road

    2100 Rock Rd, De Soto, MO

    Retail and office spaces with high visibility and full access.

    • High traffic volume on Highway 21 (13,100 VPD)
    • Full access along Rock Road
    • Great visibility
    • Office space available
    • Traffic volume on Rock Road (6,191 VPD)
    Updated: Jun 25, 2025
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    Retail Space in Downtown DeSoto
    Contact for pricing
    5,000 SF

    Retail Space in Downtown DeSoto

    De Soto, MO

    Retail space with great visibility and convenient downtown location.

    • Convenient downtown location
    • Great visibility
    • Roll up doors on end cap
    • North Main Street location
    • High traffic volume (6,973 VPD)
    Updated: Jun 24, 2025
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    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 2 Active listings in De Soto, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Festus Commercial Unit For Lease
    $1,000 /Mo

    Festus Commercial Unit For Lease

    Commercial unit on Main Street in Festus, Missouri for lease.

    206 E Main Street, Festus, MO 63028
    View details
    Retail Space in Crystal City
    Contact for pricing
    15,614 SF

    Retail Space in Crystal City

    Retail space available for lease in Crystal City, MO.

    101-105 Twin City Mall, Crystal City, MO
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    Regional Shopping Center Space Available
    Contact for pricing
    5,115 SF

    Regional Shopping Center Space Available

    Retail space available in regional shopping center with high visibility.

    110-155 Twin City Mall, Crystal City, MO
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    Festus Retail, Office, Medical Space
    Contact for pricing
    2,250 SF

    Festus Retail, Office, Medical Space

    Two spaces available in well-maintained Festus center.

    101-109 Borga Bldg, Festus, MO
    View details

    Explore Similar Spaces for Sale in De Soto, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    De Soto Retail Business Opportunity
    $850,000
    15,500 SF

    De Soto Retail Business Opportunity

    Own a business and a piece of history!

    400 S Main Street, De Soto, MO 63020
    View details
    De Soto Commercial Property
    $115,000

    De Soto Commercial Property

    Commercial property for sale in De Soto, Missouri.

    112 W Kelley Street, De Soto, MO 63020
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Cleared Lot in St Clair
    $1.00 SF/Yr

    Cleared Lot in St Clair

    1.5-acre cleared lot zoned for general commercial use.

    Saint Clair, MO 63077
    View details
    Vacant Land Near I-44
    $225,000

    Vacant Land Near I-44

    10.11 acres of vacant land with I-44 visibility.

    800 S Highway, Fenton, MO 63026
    View details
    Collinsville Commercial Space For Lease
    $5,000 /Mo
    5,000 SF

    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234
    View details
    High-Traffic Commercial Land in Rolla
    $7,500 /Mo

    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401
    View details

    De Soto, MO Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in De Soto, MO with 2 listings featured on our commercial real estate exchange. The current inventory includes 63,684,720 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in De Soto, MO begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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