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San Mateo, CA Office Properties & Spaces for Lease

54 results
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Spaces Clocktower
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Spaces Clocktower

Discover many ways to work your way in AZ, Tempe - Hayden Ferry Lake

3 3Rd Ave, San Mateo, CA 94401
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San Mateo Commercial Warehouse Lease
$7,458 / Mo
3,160 SF

San Mateo Commercial Warehouse Lease

931 N Amphlett Blvd, San Mateo, CA 94401

Versatile commercial space ideal for logistics, office, or light industrial.

  • Prime visibility from Highway 101 offering significant brand exposure.
  • Easy access to major freeways, ideal for logistics and distribution.
  • Versatile space suitable for logistics, office, or light industrial use.
  • Multiple commercial roll‑up doors for efficient operations.
  • High ceilings and open work concept design promoting efficiency.
Updated: Jan 23
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Downtown San Mateo Office Space
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Downtown San Mateo Office Space

181 2Nd Ave, San Mateo, CA 94402

Office space for lease in downtown San Mateo near Caltrain.

  • Convenient downtown San Mateo location
  • Walking distance to San Mateo Caltrain station
  • Features 4 private offices
  • Waiting area
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San Mateo Office Space Available
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San Mateo Office Space Available

Office space for lease in easily accessible San Mateo location.

205 E 3Rd Ave, San Mateo, CA 94401
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Downtown San Mateo Office Space
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Downtown San Mateo Office Space

Office space for lease in downtown San Mateo with on-site parking.

2 West 5Th Ave, San Mateo, CA 94402
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Remodeled Office Space For Rent
$1,900 / Mo

Remodeled Office Space For Rent

650 sq ft remodeled office space with parking included.

116 E 25Th Ave, San Mateo, CA 94403
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San Mateo Office Space Available
$2,775 / Mo

San Mateo Office Space Available

Second-floor office space with new floors and ample natural light.

100 N B St, San Mateo, CA 94401
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Downtown San Mateo Office Space
$3 SF/Yr
2,740 SF

Downtown San Mateo Office Space

Office space in downtown San Mateo with open layout.

2-98 E 4Th Ave, San Mateo, CA 94401
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Downtown San Mateo Office Space
$6 SF/Yr
1,729 SF

Downtown San Mateo Office Space

Office space near Caltrain station with private offices.

159-181 2Nd Ave, San Mateo, CA 94401
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San Mateo Office Space Available
$3 SF/Yr
7,337 SF

San Mateo Office Space Available

Office space available for lease in San Mateo, CA.

485-493 S El Camino Real, San Mateo, CA 94401
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Downtown San Mateo Office Space
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Downtown San Mateo Office Space

Class A+ office building with large floorplates and sustainable design.

200 E 4Th Ave, San Mateo, CA 94401
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Life Science Conversion Office Space
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Life Science Conversion Office Space

Office space for rent, life science conversion, available Q2 2024.

901 Mariners Island Blvd, San Mateo, CA 94404
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San Mateo Office Space Available
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San Mateo Office Space Available

Office space for lease with easy access to major freeways.

1300 S El Camino Real, San Mateo, CA 94402
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Professional/Medical Office Space Available
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Professional/Medical Office Space Available

Professional/Medical office space for lease, near San Francisco International Airport.

312 N San Mateo Dr, San Mateo, CA 94401
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Office Space with Modern Amenities
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Office Space with Modern Amenities

Office space for lease with convenient highway access and modern amenities.

777 Mariners Island Blvd, San Mateo, CA 94404
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Downtown San Mateo Retail Opportunity
$3,675 / Mo

Downtown San Mateo Retail Opportunity

Prime commercial space in vibrant downtown San Mateo location.

153 E 5Th Ave, San Mateo, CA 94401
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San Mateo Creative/R&D Space
$1.99 SF/Yr
1,500 SF

San Mateo Creative/R&D Space

Newly remodeled 1,500 SF creative/R&D space for lease.

938 S Amphlett Blvd, San Mateo, CA 94402
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Downtown San Mateo Office Space
$3 SF/Yr
906 SF

Downtown San Mateo Office Space

Modern office suites in the heart of downtown San Mateo.

217 B St, San Mateo, CA 94401
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Class A Office/Laboratory Space
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15,617 SF

Class A Office/Laboratory Space

Office and laboratory space with amenities and shuttle service.

1900 Alameda De Las Pulgas, San Mateo, CA 94403
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Life Science Ready Full Floor
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Life Science Ready Full Floor

Full floor life science conversion available Q2 2024.

951 Mariners Is Blvd- U/R, San Mateo, CA 94404
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Downtown San Mateo Office Building
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5,000 SF

Downtown San Mateo Office Building

Premier San Mateo office building with modern amenities for lease.

37 E 4Th Ave, San Mateo, CA 94401
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San Mateo Serviced Office Space
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2,000 SF

San Mateo Serviced Office Space

Serviced office space with flexible options and comprehensive amenities.

55 E 3Rd Ave, San Mateo, CA 94401
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Creative Office Space For Rent
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6,100 SF

Creative Office Space For Rent

Creative office space with open ceilings, balcony, and kitchen.

316 S Eldorado St, San Mateo, CA 94401
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Medical Office Space Available
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1,340 SF

Medical Office Space Available

Medical office space with existing dental infrastructure for lease.

36 N San Mateo Dr, San Mateo, CA 94401
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San Mateo, CA Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in San Mateo, CA with 59 listings featured on our commercial real estate exchange. The current inventory includes 2,010,686,040 square feet of properties with an estimated lease value of $70 SF/Yr.

Estimated lease rates for Office Properties & Spaces in San Mateo, CA begin at $1.99 SF/Yr, with an average of $10 SF/Yr and extend to $28 SF/Yr.
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