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San Mateo, CA Office Spaces for Lease

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124 properties
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Two-Story Office Building
Updated: Jun 19
Two-Story Office Building

1009 S Claremont ST, San Mateo, CA 94402

$20,230/Mo
0.12 AC lot
Two‑story office building constructed in 1989
Separate server rooms with independent HVAC systems
400 AMP electrical service
Five bathrooms, including one with a shower
Security package includes alarms, cameras, and electronic door access
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Renovated Office Space Near Caltrain
Updated: Apr 8
Renovated Office Space Near Caltrain

201 S B Street, San Mateo, CA 94401

$6.25 SF/Yr
12,320 sqft
±12,320 RSF for Lease
Walking Distance to Caltrain, Restaurants, and Other Desirable Amenities
Newly Renovated Building
Available 11/1/2026
Potential Plug & Play
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Second-Floor Office Suite with Skylights
Second-Floor Office Suite with Skylights

2575 Flores ST, San Mateo, CA 94403

$12,000/Mo
3,847 sqft

Second-floor suite with open flexible layout, full glass wraparound, skylights, HVAC, and kitchenette.

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Flexible workspace at Spaces Clocktower. Contact us today to book a tour!
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Office Campus
Office Campus

177 Bovet Rd, San Mateo, CA 94402

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6,486 sqft

Office campus in San Mateo offering on-site and walkable amenities for professional and tech users.

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Crossroads II Office Units
Crossroads II Office Units

1875 S Grant St, San Mateo, CA 94402

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4,827 sqft

Office units are offered for lease or sublease within a named commercial property.

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Office Unit in Campus Setting
Office Unit in Campus Setting

177 Bovet Rd, San Mateo, CA 94402

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3,068 sqft

Professional office space within a large Peninsula campus with convenient highway access and nearby amenities.

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Office Units with Workstations
Office Units with Workstations

435 E 3rd Ave, San Mateo, CA 94401

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10,622 sqft

Includes 43 benching workstations, private offices, and multiple conference rooms for office teams.

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Office Space with Outdoor Courtyard
Office Space with Outdoor Courtyard

1450 Fashion Island Blvd, San Mateo, CA 94404

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13,407 sqft

Office space offers courtyard seating and outdoor meeting areas, with plug-and-play options on select floors.

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Three-Story Office Space for Lease
Three-Story Office Space for Lease

2 E 3rd Ave, San Mateo, CA 94401

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10,201 sqft

Three-story office space divisible by floor with on-site showers and employee and customer parking nearby.

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Office Suite with Private Offices
Office Suite with Private Offices

1840 Gateway Dr, San Mateo, CA 94402

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21,315 sqft

Office suite offering private offices, a conference room, reception, IT, and shared break and open office space.

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Plug-and-Play Office Space
Plug-and-Play Office Space

1450 Fashion Island Blvd, San Mateo, CA 94404

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5,650 sqft

Office space offers courtyard seating and outdoor meeting space, with plug-and-play options on the 4th and 6th floors.

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Office Campus Near Major Interchange
Office Campus Near Major Interchange

177 Bovet Rd, San Mateo, CA 94402

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16,047 sqft

Office campus with on-site and walkable amenities near the HWY 92/101 interchange.

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Office Suite for Lease
Office Suite for Lease

411 Borel Avenue, San Mateo, CA 94402

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4,640 sqft

Well-suited office suite available for lease at 411 Borel Ave, Unit 101 in San Mateo.

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Office Suite with Multiple Rooms
Office Suite with Multiple Rooms

435 E 3rd Ave, San Mateo, CA 94401

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10,665 sqft

Well-appointed office space featuring workstations, private offices, conference rooms, and a tenant lobby.

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Office Space with Panoramic Views
Office Space with Panoramic Views

1730 S El Camino Real, San Mateo, CA 94402

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3,994 sqft

Office space with covered parking and a common conference facility, with Caltrain within a 7-minute walk.

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Live-Work Building with Roof Decks
Live-Work Building with Roof Decks

500 E 3rd Ave, San Mateo, CA 94401

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63,616 sqft

Five-floor office space with exterior roof decks, 2 levels of underground parking, and 111 residential units with separate entrance.

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Class A Office and Retail Building
Class A Office and Retail Building

2 E 3rd Ave, San Mateo, CA 94401

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10,389 sqft

Three-story building offers divisible office space with signage exposure and convenient on-site showers and parking.

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Plug-and-Play Office Floors
Plug-and-Play Office Floors

1450 Fashion Island Blvd, San Mateo, CA 94404

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2,686 sqft

Office space offering available building signage, courtyard seating, and shuttle access, with plug-and-play setups on select floors.

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Class A Office and Retail Building
Class A Office and Retail Building

2 E 3rd Ave, San Mateo, CA 94401

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4,754 sqft

Three-story Class A building with on-site showers, bicycle parking, and divisible office and retail space.

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Plug-and-Play Office Suites
Plug-and-Play Office Suites

1450 Fashion Island Boulevard, San Mateo, CA 94404

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45,756 sqft

Office suites with potential building signage on 4th and 6th floors.

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Office Building with Fitness Facility
Office Building with Fitness Facility

1001 E Hillsdale Blvd, San Mateo, CA 94404

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7,772 sqft

Modern office environment featuring a fitness facility with showers and lockers, plus EV charging and secured parking.

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Crossroads I Office Space
Crossroads I Office Space

1825 S Grant St, San Mateo, CA 94402

Contact for pricing
2,286 sqft

Crossroads I offers office space ranging from 4,480 to 7,260 square feet for lease.

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San Mateo Office Space Available
San Mateo Office Space Available

177 Bovet Rd, San Mateo, CA 94402

Contact for pricing
3,068 sqft

Office space for lease in San Mateo, ranging from 3,068-16,047 SF.

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San Mateo, CA Office Spaces Lease Rates & Market Statistics

Explore 124 Office Spaces for lease in San Mateo, CA on Realmo, a commercial real estate exchange covering the San Mateo area. The current inventory totals 1,731,096 square feet of properties — an average of ~13,950 SF per listing.

Office Spaces lease rates in San Mateo range from $6.25 SF/Yr at the entry level to $75 SF/Yr at the top of the market, averaging $39.56 SF/Yr. That's a 12x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $39.56 SF/Yr, the local average runs 58% above California's state average of $24.97 SF/Yr.

San Mateo accounts for 8% of the 1,599 office spaces currently available across San Mateo County, where nearby markets include San Francisco and Redwood City. By space type, the market includes 79 office units, 45 office buildings and 4 medical office space listings.

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