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San Francisco, CA Office Units for Lease

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504 results
San Francisco Commercial Space Available
$8,000 /Mo
3,795 SF

San Francisco Commercial Space Available

729 Bush Street, San Francisco, CA 94108

Two-story commercial building in Lower Nob Hill for rent.

  • Prime location in Lower Nob Hill, San Francisco, near Union Square and the Financial District
  • Versatile RC‑4 zoning allows for a wide range of commercial uses
  • Rare large 3,781 sq ft lot for the area
  • Excellent transportation access via BART, cable cars, and MUNI
  • Redevelopment potential, including vertical expansion and modern medical build‑outs
Updated: Aug 1, 2025
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Mission District Tech Office Space
$60 SF/Yr
10,000 SF

Mission District Tech Office Space

3043 Mission, San Francisco, CA 94110

High-end office space in vibrant Mission District, San Francisco.

  • Two full floors of high‑end, tech‑oriented space.
  • Prime location on 25th and Mission, near restaurants, shops, bars, and parks.
  • Convenient access to transportation: two blocks from BART and direct Muni lines.
  • Six private offices, two conference rooms, and two kitchens.
  • Exposed concrete aesthetic and wall‑to‑wall window frontage.
Updated: Jan 27
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Move-in Ready Office Space Available
$15 SF/Yr
10,800 SF

Move-in Ready Office Space Available

Three floors of office space in a convenient San Francisco location.

1338 Mission St, San Francisco, CA 94103
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Modern Office Space in South Park
$42 SF/Yr
6,200 SF

Modern Office Space in South Park

Newly renovated office space with high ceilings and great natural light.

536 bryant, San Francisco, CA 94107
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San Francisco Commercial Space For Rent
$5,200 /Mo
1,150 SF

San Francisco Commercial Space For Rent

Commercial space available for rent in San Francisco, CA.

1122 Clement Street 2, San Francisco, CA 94118
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San Francisco Commercial Space Available
$13,500 /Mo
4,800 SF

San Francisco Commercial Space Available

4800 SF retail/office space for rent in San Francisco.

365 10th Street, San Francisco, CA 94103
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Versatile Office Space in San Francisco
$45 SF/Yr
16,900 SF

Versatile Office Space in San Francisco

Varied office solutions in a convenient Financial District location.

665 Chestnut Street, San Francisco, CA 94133
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San Francisco Office Space Available
$45 SF/Yr
2,035 SF

San Francisco Office Space Available

Office space for lease in San Francisco with exposed brick.

45 Belden Pl, San Francisco, CA 94104
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Historic Orpheum Theatre Office Space
$18 SF/Yr
117,000 SF

Historic Orpheum Theatre Office Space

Boutique office suites in a distinguished, secure, and welcoming community.

1182 Market Street, San Francisco, CA 94102
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Creative Space in SOMA District
$22 SF/Yr
62,000 SF

Creative Space in SOMA District

Unique creative space in a prime SOMA location for rent.

972 Mission Street, San Francisco, CA 94103
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San Francisco Commercial Space Available
$4,350 /Mo
2,500 SF

San Francisco Commercial Space Available

Commercial space available for rent in San Francisco, CA.

1340 Van Dyke Avenue, San Francisco, CA 94124
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San Francisco Commercial Space Available
$6,000 /Mo
6,401 SF

San Francisco Commercial Space Available

Commercial space for rent in San Francisco, California.

1666 Lombard Street 1662A, San Francisco, CA 94123
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Glen Park Office/Retail Space
$45 SF/Yr
5,400 SF

Glen Park Office/Retail Space

High-quality office/retail space in the heart of Glen Park.

605 Chenery Street, San Francisco, CA 94131
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San Francisco Commercial Space Available
$13,000 /Mo
3,332 SF

San Francisco Commercial Space Available

Commercial space for rent in San Francisco, CA.

1315 7th Avenue, San Francisco, CA 94122
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Prime North Waterfront Office Space
$55 SF/Yr
92,836 SF

Prime North Waterfront Office Space

Office space for rent in a vibrant tourist destination.

2552 Taylor, San Francisco, CA 94133
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Bright Office Space For Rent
$1,000 /Mo

Bright Office Space For Rent

Spacious 2-room office with sink and storage in San Francisco.

9 Silliman St, San Francisco, CA 94134
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Brick and Timber Office Suites
$50 SF/Yr
18,000 SF

Brick and Timber Office Suites

Turnkey office suites in San Francisco's vibrant Mission District.

2180 Bryant, San Francisco, CA 94110
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Full Floor Medical Office Space
$1.75 SF/Yr
4,367 SF

Full Floor Medical Office Space

Full floor medical suite with exam and private offices.

1833 Fillmore St, San Francisco, CA
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Modern Office Space with Amenities
$55 SF/Yr
2,784 SF

Modern Office Space with Amenities

Office space with health club, parking, and excellent amenities.

2200 Powell St, San Francisco, CA
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Jackson Square Office Space Available
$85 SF/Yr
5,400 SF

Jackson Square Office Space Available

Sublease opportunity in Jackson Square with creative finishes.

402 Jackson St, San Francisco, CA 94111
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Retail/Office Space in San Francisco
$5,500 /Mo
1,400 SF

Retail/Office Space in San Francisco

1400 SF retail or office space available for rent.

1377 9TH Avenue, San Francisco, CA 94122
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Furnished Office Space with Amenities
$58 SF/Yr
11,061 SF

Furnished Office Space with Amenities

Class A, LEED Platinum certified office space for rent.

100 - 150 Hooper St, San Francisco, CA
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Updated Office Space For Rent
$1.65 SF/Yr
9,519 SF

Updated Office Space For Rent

Updated office space with open floorplan, private offices, and conference rooms.

490 2nd St, San Francisco, CA
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San Francisco Retail/Office Space
$6,000 /Mo
1,500 SF

San Francisco Retail/Office Space

Retail or office space available for rent in San Francisco.

643 Mission Street, San Francisco, CA 94105
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San Francisco, CA Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in San Francisco, CA with 504 listings featured on our commercial real estate exchange. The current inventory includes 8,688,477,600 square feet of properties with an estimated lease value of $1,377 /Mo.

Estimated lease rates for Office Units in San Francisco, CA begin at $1.00 SF/Yr, with an average of $30 SF/Yr and extend to $71 SF/Yr.
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