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    San Diego, CA Office Spaces for Lease

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    Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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    Corner Retail Space
    Corner Retail Space

    2550 Fifth Ave, San Diego, CA 92103

    Park West
    Contact for pricing
    Multi-tenant  3,270 sqft  164,000 GLA
    Mister A's co-tenants  Corner location

    Retail space at the base of a Class A office building with 430 on-site parking spaces and high-traffic intersection frontage.

    430 parking spaces
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    Rancho Bernardo Plug & Play Office
    Rancho Bernardo Plug & Play Office

    11545 W. Bernardo Ct., Suite 305, San Diego, CA 92127

    Rancho Bernardo
    Contact for pricing
    15–25 people  3,801 sqft

    Plug & Play office suite in Rancho Bernardo available for sublease.

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    Office Building for Lease
    Office Building for Lease

    5555 Reservoir Dr., San Diego, CA 92120

    College East
    Contact for pricing
    41–69 people  3 spaces  10,403 sqft  Built 2026

    Office building available for rent at 5555 Reservoir Dr. in San Diego.

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    Office Space for Lease
    Office Space for Lease

    3033 5th Ave., San Diego, CA 92103

    Park West
    Contact for pricing
    8–13 people  1 space  2,027 sqft  Built 2027

    Office space available for lease at 3033 5th Ave., with a listed property size of 2,027.

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    Class A Creative Space
    Class A Creative Space

    9855 Scranton Road, San Diego, CA 92121

    Class A Sorrento Valley
    Contact for pricing
    191–318 people  47,818 sqft

    San Diego campus includes fitness, recreation, dining amenities, and a WiredScore Platinum designation.

    Fitness center  Amenity park  Sport courts & fields  Dining options
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    Office Space Available For Lease
    Office Space Available For Lease

    6699 Alvarado Rd., San Diego, CA 92120

    College East
    Contact for pricing
    22–38 people  5,737 sqft  Built 2026

    Office space available for lease in San Diego, CA.

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    Office Space with Showers
    Office Space with Showers

    11010 Roselle St, San Diego, CA 92121

    Torrey Pines
    Contact for pricing
    62–103 people  15,500 sqft
    Highway access

    Office suite includes restrooms and showers and offers immediate access to I-5 and I-805.

    Restrooms & Showers  Walkable to Coaster & Area Amenities
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    Class A Office Space
    Class A Office Space

    13520 Evening Creek Dr N, San Diego, CA 92128

    Sabre Springs
    Contact for pricing
    21–35 people  5,255 sqft

    Modern office amenities include on-site management and security, EV charging, and outdoor meeting areas with WiFi access.

    View details
    Lab-Ready Office Units
    Lab-Ready Office Units

    9276 Scranton Road, San Diego, CA 92121

    Class A Sorrento Valley
    Contact for pricing
    53–89 people  13,352 sqft
    Highway access

    Office units within a life science campus with lab infrastructure, expansive floorplates, and tenant-focused amenities.

    Fitness Center & Classes  Car Detailing Services  On-Site Dry Cleaning  California English
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    Ground-Floor Retail and Office
    Ground-Floor Retail and Office

    1253 University Ave, San Diego, CA 92103

    Hillcrest
    Contact for pricing
    3,045 sqft
    22,926 VPD

    Ground-floor retail and second-floor office space available with modern interiors and 8 parking spaces.

    8 parking spaces
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    Plug-and-Play Modern Office Suite
    Plug-and-Play Modern Office Suite

    12626 High Bluff Drive, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    26–44 people  1 space  6,732 sqft

    New modern office suite features glass-lined interiors, two conference rooms, and direct access to a shared patio.

    5 parking spaces  Two Conference Rooms  Direct Access to Shared Patio Space  Double Door Elevator Lobby Exposure
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    Office Space Available For Sublease
    Office Space Available For Sublease

    5887 Copley Dr, San Diego, CA 92111

    Kearny Mesa
    Contact for pricing
    152–254 people  38,244 sqft

    Office building II sublease opportunity in San Diego, California.

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    Fitness and Wellness Center
    Fitness and Wellness Center

    12520 High Bluff Dr, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    14–24 people  1 space  3,693 sqft

    Fitness + wellness center with restrooms and showers, covered parking, and a conference center.

    Restrooms & Showers  Fitness + Wellness Center  Covered Parking  Conference Center
    View details
    San Diego Office Space Available
    San Diego Office Space Available

    600 W. Broadway, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    54–91 people  2 spaces  13,669 sqft  Built 2026

    Prime office space available for lease in San Diego.

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    Spec Office Suite with Double-Door Entry
    Spec Office Suite with Double-Door Entry

    11455 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    21–36 people  5,474 sqft

    Ground-floor spec office suite with reception, private offices, conference space, and workstation area.

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    Renovated Class A Office Building
    Renovated Class A Office Building

    8954 Rio San Diego Dr, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    17–29 people  4,389 sqft

    Class A office building with renovated lobby and fitness facility.

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    Kearny Mesa Class A Office
    Kearny Mesa Class A Office

    4995 Murphy Canyon Rd, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    13–21 people  3,277 sqft

    Class A office space in Kearny Mesa for lease.

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    Office Space for Sublease
    Office Space for Sublease

    16959 Bernardo Center Drive, San Diego, CA 92128

    Rancho Bernardo
    Contact for pricing
    7–12 people  1,877 sqft

    Office space available for sublease in San Diego, CA.

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    Office Space for Lease
    Office Space for Lease

    2535 Midway Dr., San Diego, CA 92110

    Midway District
    Contact for pricing
    920–1,533 people  230,000 sqft  Built 2026

    Office space is available for lease at 2535 Midway Dr. in San Diego.

    View details
    San Diego Commercial Space Available
    San Diego Commercial Space Available

    9360-9420 Activity Rd., San Diego, CA 92126

    Mira Mesa
    Contact for pricing
    8,472 sqft  Built 2026

    Commercial space for lease in San Diego, California.

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    Furnished Two-Story R&D Office
    Furnished Two-Story R&D Office

    9707 Waples Street, San Diego, CA 92121

    Gross Sorrento Valley
    Contact for pricing
    51–85 people  1 space  12,775 sqft  2-story

    Two-story R&D office building with furnished interiors, signage, and an outdoor amenity area with volleyball courts.

    Furnished  Building and monument signage  Outdoor amenity area  Volleyball courts
    View details
    Class A Office Building
    Class A Office Building

    13520 Evening Creek Dr N, San Diego, CA 92128

    Class A Sabre Springs
    Contact for pricing
    12–20 people  3,117 sqft
    Public transit

    On-site management and security with access to the 56 bike path and MTS Station.

    4.0/1,000 SF parking  Fitness center with shower and locker facilities  Outdoor meeting areas with free WiFi  EV charging stations
    View details
    Office Space for Lease
    Office Space for Lease

    2878 Camino Del Rio S, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    7–12 people  1,829 sqft

    For-lease office space available at 2878 Camino Del Rio S in San Diego.

    View details
    Freeway Visible Office Space
    Freeway Visible Office Space

    10680 Treena St, San Diego, CA 92131

    Scripps Ranch
    Contact for pricing
    17–29 people  4,366 sqft

    Office space with high parking ratio and freeway visibility.

    View details
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    • 92121
    • 92101
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    • 92110
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