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    San Diego, CA Office Spaces for Lease

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    Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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    Office Space
    Office Space

    3323 Carmel Mountain Rd, San Diego, CA 92121

    Torrey Preserve
    Contact for pricing
    10–17 people  2,600 sqft

    Office space includes open office, private offices, a utility room, and restroom.

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    Lab-Ready Office Suite
    Lab-Ready Office Suite

    3550 General Atomics Ct, San Diego, CA 92121

    Torrey Pines
    Contact for pricing
    23–39 people  29 spaces  5,955 sqft

    Office suite with existing lab benches and sinks, plus mezzanine space that can convert to office.

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    Future Spec Office Suite
    Future Spec Office Suite

    600 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    9–16 people  2,458 sqft

    Planned office suite with double door entry and build-out for reception, private offices, conference room, break area, and workstations.

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    Modernized Office Space in Sorrento
    Modernized Office Space in Sorrento

    5465 Morehouse Drive, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    13–21 people  3,292 sqft

    Office space in San Diego's technology hub, Sorrento Mesa.

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    Office Suite with Private Offices
    Office Suite with Private Offices

    7930 Arjons Dr, San Diego, CA 92126

    Mira Mesa
    Contact for pricing
    20–34 people  1 space  5,128 sqft

    Office suite featuring reception, five private offices, open office area, and two restrooms.

    Reception  Private offices  Open office area  Kitchen/break room
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    Class A Medical Office Space
    Class A Medical Office Space

    8008 Frost Street, San Diego, CA 92123

    Birdland
    Contact for pricing
    9,337 sqft

    Medical office space available in a three-building campus.

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    Office Building in San Diego
    Office Building in San Diego

    2100 Kettner Blvd, San Diego, CA 92101

    Little Italy
    $5.50 SF/Yr
    936–1,560 people  234,000 sqft

    Office building with 234,000 square feet available for rent.

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    Class A Creative Space
    Class A Creative Space

    10055 Barnes Canyon Rd, San Diego, CA 92121

    Class A Sorrento Valley
    Contact for pricing
    56–94 people  14,171 sqft

    Creative workspace within a professionally operated campus featuring fitness, recreation, dining, and technology infrastructure.

    Professionally operated indoor/outdoor fitness center  Amenity Park  Sport courts & fields  Dining options serving craft coffee, lunch and dinner/drinks
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    Creative Office Suite with Corner Views
    Creative Office Suite with Corner Views

    404 Camino del Rio S, San Diego, CA 92108

    Mission Valley West
    Contact for pricing
    9–15 people  2,314 sqft

    Corner creative office suite features a floor-to-ceiling window line and potential expansion to a larger footprint.

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    Flex Office Suite with Two Offices
    Flex Office Suite with Two Offices

    11235 W Bernardo Ct, San Diego, CA 92127

    Rancho Bernardo
    Contact for pricing
    8,573 sqft

    Flex office suite offering two private offices, a breakroom, and an open office area.

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    Professional Office Suite
    Professional Office Suite

    6155 E Cornerstone Ct, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    20–34 people  2 spaces  5,190 sqft

    For rent professional office space within a larger office building in San Diego.

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    Office Units Available For Lease
    Office Units Available For Lease

    7843 Girard Ave, La Jolla, CA 92037

    Contact for pricing
    2–4 people  650 sqft

    Office units are available for lease in La Jolla.

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    Upgraded Lab Office Suites
    Upgraded Lab Office Suites

    12250 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    19–32 people  4,900 sqft

    Upgraded office suites with robust MEP systems, offering multiple lab suite sizes within a large building.

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    Medical Office Suite with Abundant Parking
    Medical Office Suite with Abundant Parking

    9834 Genesee Ave., La Jolla, CA 92037

    Full service
    Contact for pricing
    16,193 sqft  Built 2026
    Highway access

    Full-service gross rent includes electricity and janitorial, with convenient access off the I-5 freeway.

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    La Jolla Office Space Available
    La Jolla Office Space Available

    7825 Fay Ave, La Jolla, CA 92037

    Contact for pricing
    6–10 people  1,621 sqft

    Office space for lease in the Merrill Lynch Building.

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    Creative Office Space For Lease
    Creative Office Space For Lease

    2251 San Diego Ave, San Diego, CA 92110

    Old Town
    Contact for pricing
    1 person  293 sqft

    Creative office space with secure parking and high-speed internet.

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    Premier Del Mar Office Space
    Premier Del Mar Office Space

    12555 High Bluff Dr, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    9–15 people  2,346 sqft

    Class A office with upgraded interiors and tranquil courtyard.

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    San Diego Office/Lab Space Available
    San Diego Office/Lab Space Available

    10201 Wateridge Cir, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    35–59 people  8,919 sqft

    Office space, converted to lab, available for lease.

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    Upgraded Lab-Ready Office Suites
    Upgraded Lab-Ready Office Suites

    12250 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    44–73 people  11,000 sqft

    Office suites sized from 4,500 to 11,800 SF within an upgraded building designed for laboratory MEP needs.

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    Ocean-View Retail Space
    Ocean-View Retail Space

    1250 Prospect St, La Jolla, CA 92037

    Contact for pricing
    1,393 sqft

    Retail space along Prospect Street in a walkable coastal district near dining, boutiques, galleries, and attractions.

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    Class A Office Tower with Retail
    Class A Office Tower with Retail

    401 W A St, San Diego, CA 92101

    Class A Core-Columbia
    Contact for pricing
    16–27 people  4,149 sqft  27-story

    Premier Class A 27-story office tower with 30,514 square feet of retail and 498 subterranean parking spaces.

    498 parking spaces  Plaza terrace
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    Upgraded Office Suites with Fitness Center
    Upgraded Office Suites with Fitness Center

    12770 High Bluff Dr, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    7–13 people  1,983 sqft
    Highway access

    Highlands Corporate Center offers upgraded office suites with collaborative indoor/outdoor lounges and a fully equipped fitness center.

    Collaborative indoor and outdoor lounge areas  Fitness center  Outdoor tenant spaces
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    Upgraded Lab Office Building
    Upgraded Lab Office Building

    12250 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    18–30 people  4,500 sqft

    86,000-square-foot facility with upgraded MEP systems supporting laboratory-ready office lab suites.

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    La Jolla Office Space Available
    La Jolla Office Space Available

    800 Silverado St, La Jolla, CA 92037

    Contact for pricing
    13–22 people  3,370 sqft

    Office space for rent in the heart of La Jolla.

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    Most Searched ZIP Codes in San Diego, CA

    • 92121
    • 92101
    • 92123
    • 92130
    • 92108
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    • 92131
    • 92110
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