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San Diego, CA Office Spaces for Lease

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Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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Amenitized Office Campus in San Diego
Amenitized Office Campus in San Diego

16855 West Bernardo Drive, San Diego, CA 92127

Rancho Bernardo
Contact for pricing
79–132 people  19,928 sqft

Rancho Bernardo office campus with amenities and flexible suites.

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Office Space Available For Rent
Office Space Available For Rent

10021 Willow Creek Rd, San Diego, CA 92131

Scripps Ranch
Contact for pricing
30–50 people  7,615 sqft

7,615 square foot office space available for rent.

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Renovated Office Space with Views
Renovated Office Space with Views

10616 Scripps Summit Ct, San Diego, CA 92131

Miramar Ranch North
Contact for pricing
100–166 people  25,000 sqft

Newly renovated office space with panoramic views and freeway access.

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Office Suite with Private Offices
Office Suite with Private Offices

3333 N Torrey Pines Ct, La Jolla, CA 92037

Contact for pricing
52–87 people  13,165 sqft

Office suite offering 20 private offices, conference rooms, and shared work and break areas.

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Four-Story Garden Office Building
Four-Story Garden Office Building

7777 Fay Ave, La Jolla, CA 92037

Class A
Contact for pricing
9–16 people  2,430 sqft  4-story

Class A garden office building with building signage opportunity and close proximity to La Jolla Cove and the Pacific Ocean.

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Office Suite with Board Room
Office Suite with Board Room

3333 N Torrey Pines Ct, La Jolla, CA 92037

Contact for pricing
34–57 people  8,588 sqft

Office suite features 11 private offices, a large board room, break area, and open office space.

11 private offices  Large board room  Break area  IT room
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La Jolla Office Space For Rent
La Jolla Office Space For Rent

San Diego, CA

Little Italy
Contact for pricing
36–60 people  9,095 sqft  1.98 acres

Shell office space with direct entry and ocean views.

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Three-Story Office Building For Rent
Three-Story Office Building For Rent

8989 Rio San Diego Dr, San Diego, CA 92108

Mission Valley East
Contact for pricing
8–13 people  2,039 sqft

78,388 SF office building with freeway access and amenities.

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San Diego Lab and Office
San Diego Lab and Office

10480 Wateridge Cir, San Diego, CA 92121

Sorrento Valley
Contact for pricing
15,603 sqft

15,603 SF lab and office space for rent.

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Office Building with On-Site Fitness Center
Office Building with On-Site Fitness Center

3661 Valley Centre Dr, San Diego, CA 92130

Torrey Preserve
Contact for pricing
18–30 people  4,558 sqft
Highway access

Office space in a LEED and Energy Star-rated complex with on-site fitness and EV charging.

4.0/1,000 SF parking  Fitness center  EV charging stations  Car wash
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Medical Office Suite with Balcony Access
Medical Office Suite with Balcony Access

12264 El Camino Real, San Diego, CA 92130

Torrey Preserve
Contact for pricing
4,473 sqft  4-story
Highway access  Road access

Medical office suite in a Class A building with shared balcony access and abundant covered and surface parking.

Shared balcony / outdoor space  On-site athletic facility  Upgraded common areas  Fiber optic cable available
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Professional Office Space Available
Professional Office Space Available

3160 Camino Del Rio S, San Diego, CA

Adams North
Contact for pricing
5–9 people  3 spaces  1,384 sqft  4.05 acres

Corporate image, renovated common areas, and highway access.

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Premier Office Building with Courtyard
Premier Office Building with Courtyard

5120 Shoreham Place, San Diego, CA 92122

University City
Contact for pricing
7–13 people  1 space  1,963 sqft

Courtyard-style office building in the Golden Triangle area.

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Dynamic San Diego Office Campus
Dynamic San Diego Office Campus

9635, 9645, 9655 & 9665 Granite Ridge Dr, San Diego, CA 92123

Serra Mesa
Contact for pricing
347–578 people  86,777 sqft

First-class office campus with robust amenities and freeway access.

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San Diego Office Space Available
San Diego Office Space Available

2550 5th Ave., San Diego, CA 92103

Park West
Contact for pricing
110–183 people  27,505 sqft  Built 2026

Office building with 27,505 square feet available for rent.

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Premier Office Space Available
Premier Office Space Available

3721 Valley Centre Dr, San Diego, CA

Torrey Preserve
Contact for pricing
24–40 people  6,149 sqft  2.46 acres

Modern office space with excellent amenities and freeway visibility.

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Contiguous Office Suites
Contiguous Office Suites

101 W Broadway, San Diego, CA 92101

Horton Plaza
Contact for pricing
12–21 people  3,166 sqft

Office suite build-out includes reception, conference room, private offices, and open workstation space.

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Office Suite with Private Patio
Office Suite with Private Patio

12264 El Camino Real, San Diego, CA 92130

Class A Torrey Preserve
Contact for pricing
10–17 people  2,577 sqft  4-story
Highway access

Shell-condition office suite includes private office, storage room, and a private patio within a Class A office/medical building.

On-site athletic facility  Recently upgraded common areas  Fiber optic cable available  Balcony access in select suites
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Office Space with EV Charging
Office Space with EV Charging

3661 Valley Centre Dr, San Diego, CA 92130

Torrey Preserve
Contact for pricing
22–36 people  5,524 sqft

Office building offers EV charging, on-site amenities, and strong freeway visibility with structured parking and 24-hour security staffing.

On-site fitness center with shower and locker facilities  Unparalleled freeway visibility  EV charging stations  LEED and Energy Star rated features
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Multi-Office Suite With Ocean Views
Multi-Office Suite With Ocean Views

3333 N Torrey Pines Ct, La Jolla, CA 92037

Contact for pricing
19–33 people  4,990 sqft
9 private offices  4 meeting rooms

Flexible office layout with private rooms, collaborative areas, and an outdoor patio overlooking the ocean.

Break area  Outdoor patio w/ ocean views
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Available Office Space in San Diego
Available Office Space in San Diego

5060 Shoreham Pl, San Diego, CA 92122

University City
Contact for pricing
22–37 people  5,587 sqft

Office space available for rent in San Diego, California.

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Class A Medical Office Suites
Class A Medical Office Suites

8010 Frost Street, San Diego, CA 92123

Birdland
Contact for pricing
Multi-tenant
Highway access

Class A medical office suites within a three-building campus with structured and surface parking.

On-site professional property management
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Murphy Canyon Office Space Available
Murphy Canyon Office Space Available

3914 Murphy Canyon, San Diego, CA 92123

Kearny Mesa
Contact for pricing
35–59 people  9 spaces  8,864 sqft  Built 2026

Office space available for rent in San Diego, CA.

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Banker's Hill Office Space Available
Banker's Hill Office Space Available

2970 Fifth Avenue, San Diego, CA 92103

Park West
Contact for pricing
34–57 people  8,577 sqft

Office space for rent in Banker's Hill neighborhood.

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