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    San Diego, CA Office Spaces for Lease

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    Found 558 office space listings for lease in San Diego, CA, averaging $21/SF/YR. Use lease type data to compare options faster.
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    Office Space Available For Rent
    Office Space Available For Rent

    9201 Spectrum Center Blvd, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    58–98 people  14,745 sqft

    Office space available for lease in San Diego, CA.

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    Office Space Available For Rent
    Office Space Available For Rent

    13400 Sabre Springs Pkwy, San Diego, CA 92128

    Sabre Springs
    Contact for pricing
    22–36 people  5,515 sqft

    Office space available for lease in San Diego, CA

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    Office Space Available For Rent
    Office Space Available For Rent

    6310 Greenwich Dr, San Diego, CA 92122

    University City
    Contact for pricing
    11–19 people  2,944 sqft

    Office space available for rent in San Diego, CA.

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    Two-Story Corporate Office Building
    Two-Story Corporate Office Building

    5855 Copley Drive, San Diego, CA 92111

    Kearny Mesa
    Contact for pricing
    161–268 people  40,335 sqft  2-story
    Highway access

    Two-story office building with upgraded corridors, onsite fitness, outdoor lounge areas, and substantial parking.

    Abundant Parking  Signage Available  Fitness Center  Outdoor Lounge Areas
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    Convenient Office Space Near I-15
    Convenient Office Space Near I-15

    3655 Ruffin Rd., San Diego, CA 92123

    Serra Mesa
    Contact for pricing
    82–136 people  20,519 sqft

    Office space with easy access to I-15 and amenities.

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    Full-Floor Office Space with Two Entrances
    Full-Floor Office Space with Two Entrances

    101 W Broadway, San Diego, CA 92101

    Horton Plaza
    Contact for pricing
    82–137 people  20,558 sqft

    Full-floor office space with two double-door entries off the elevator lobby in downtown San Diego.

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    Class A Office Building
    Class A Office Building

    3661 Valley Centre Dr, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    56–94 people  14,103 sqft

    Office space in a LEED and Energy Star-rated building with EV charging and extensive on-site amenities.

    On-site fitness center with shower and locker facilities  Unparalleled freeway visibility  EV charging stations  LEED and Energy Star rated features
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    Renovated Class A Flex Space
    Renovated Class A Flex Space

    4215 Sorrento Valley Blvd, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    26,813 sqft

    Recently renovated Class A building with plug-and-play office area.

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    Office Space in San Diego
    Office Space in San Diego

    11011 North Torrey Pines Road, San Diego, CA 92037

    La Jolla
    Contact for pricing
    42–70 people  10,628 sqft

    Available office space for rent in San Diego, California.

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    Office Space Available For Rent
    Office Space Available For Rent

    2131 3rd Ave, San Diego, CA 92101

    Park West
    Contact for pricing
    42–70 people  10,506 sqft

    Office space available for lease in San Diego, CA.

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    Medical Office Suite with Balcony
    Medical Office Suite with Balcony

    12264 El Camino Real, San Diego, CA 92130

    Torrey Preserve
    Contact for pricing
    2,982 sqft  4-story
    Highway access

    Second-floor medical office suite offers double-door entry and access to shared balcony/outdoor space.

    Shared balcony/outdoor space  Athletic facility  Upgraded common areas  Fiber optic cable available
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    San Diego Spectrum Corporate Campus
    San Diego Spectrum Corporate Campus

    9242-9246 Lightwave Ave, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    141–235 people  35,375 sqft

    Two-building office campus in San Diego Spectrum available for lease.

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    Class A Office Space Available
    Class A Office Space Available

    10251 Vista Sorrento Parkway, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    468–780 people  117,000 sqft

    Class A office space with modern amenities for lease.

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    Office Space in San Diego
    Office Space in San Diego

    3944 Murphy Canyon Rd., San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    26–43 people  3 spaces  6,503 sqft  Built 2026

    6,503 square foot office space available for rent.

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    Office Space Available For Rent
    Office Space Available For Rent

    4375 Jutland Drive, San Diego, CA 92117

    Bay Ho
    Contact for pricing
    54–90 people  13,577 sqft

    Office space available for rent at 4375 Jutland Drive.

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    Class A Office Project
    Class A Office Project

    3420 & 3430 Carmel Mountain Rd, San Diego, CA 92121

    Torrey Preserve
    Contact for pricing
    12–21 people  3,171 sqft

    Two-building Class A office project with panoramic views available for rent.

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    Executive Drive Office Space
    Executive Drive Office Space

    4475 Executive Drive, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    54–90 people  13,613 sqft

    Office and medical space available for rent in San Diego.

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    Medical Office Space Available
    Medical Office Space Available

    12395 El Camino Real, San Diego, CA 92130

    Carmel Valley
    Contact for pricing
    11,650 sqft  Built 2026

    Medical office space for lease with ample parking.

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    San Diego Office Space Available
    San Diego Office Space Available

    5550 Morehouse Dr, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    91–151 people  22,756 sqft

    Office space for rent in San Diego, California.

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    Class A Medical Office Building
    Class A Medical Office Building

    9095 Rio San Diego Drive, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    Highway access

    Renovated common areas and restrooms in a Class A medical office building with ample parking and transit access.

    Renovated Common Area And Restrooms  Easy Access To The I-5, I-8, I-805 And I-15 Freeways  Sd Trolley Station Access
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    Three-Story Commercial Space Available
    Three-Story Commercial Space Available

    4930 Directors Place, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    93,473 sqft

    Three-story commercial space with on-site amenities for lease.

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    Kearny Mesa Office/Flex Space
    Kearny Mesa Office/Flex Space

    7854-7924 Ronson Road, San Diego, CA 92111

    Kearny Mesa
    Contact for pricing
    32,144 sqft

    Office and flex space with freeway access in Kearny Mesa.

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    Renovated Class A Office Suites
    Renovated Class A Office Suites

    10805 Rancho Bernardo Rd, San Diego, CA 92127

    Class A Black Mountain Ranch
    Contact for pricing
    20–34 people  1 space  5,160 sqft
    Highway access + Road access

    Recently renovated Class A office common areas with efficient floor plates and suite layouts.

    Class A common areas  Outdoor collaboration area with seating, barbecue and recreation area
    View details
    Second Generation Corner Office Suite
    Second Generation Corner Office Suite

    9444 Farnham St, San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    7–11 people  1,784 sqft  Built 1985

    Corner office suite featuring reception, open area, and conference room.

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    Most Searched ZIP Codes in San Diego, CA

    • 92121
    • 92101
    • 92123
    • 92130
    • 92108
    • 92128
    • 92037
    • 92127
    • 92131
    • 92110
    • 92111
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