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National City, CA Office Properties & Spaces for Lease

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South Bay Corporate Center Office
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23,721 SF

South Bay Corporate Center Office

401 Mile of Cars Way, National City, CA 91950

Office space available in South Bay Corporate Center.

  • Excellent Location: Immediately adjacent to Interstate 5 and near the South Bay Freeway (SR‑54).
  • Mass Transit Access: Adjacent to the 24th Street Transit Center (Trolley and bus service).
  • Large Floor Plates: 60,000 SF floor plates offer flexible space configurations.
  • Ample Parking: 4/1000 USF parking ratio.
  • Large Available Space: 23,721 SF available for lease.
Updated: Apr 15
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Office/R&D Building Near Interstate 5
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23,721 SF

Office/R&D Building Near Interstate 5

401 Mile of Cars Way, National City, CA

190,000 SF office/R&D building near Interstate 5.

  • Immediate adjacency to Interstate 5 and proximity to South Bay Freeway (SR‑54) offer exceptional transportation access.
  • Location adjacent to the 24th Street Transit Center (Trolley and bus service) provides convenient mass transit options.
  • Large 190,000 SF, 3‑story building suitable for office/R&D use.
  • MCR‑2 zoning allows for mixed‑use commercial/residential development.
  • High‑density employment area and a large residential population (approximately 450,000 within a 5‑mile radius) create a strong potential customer/employee base.
Updated: Aug 19, 2025
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National City Office Space Available
$1.98 SF/Yr
3,873 SF

National City Office Space Available

Office space available for rent in National City, CA.

148 E 30th St, National City, CA
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Medical Office Suites For Lease
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Medical Office Suites For Lease

Medical office suites available for lease.

655 Euclid Ave, National City, CA 91950
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Medical Office Space For Lease
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Medical Office Space For Lease

Medical office space available for lease.

502 Euclid Ave, National City, CA 91950
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Based on your search, we've compiled 15 Potential Opportunities for your consideration. Besides 5 Active listings in National City, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Explore Office properties & Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office/Medical Space for Lease
$21 SF/Yr
1,457 SF

Office/Medical Space for Lease

Office and medical space with updated finishes and free parking.

5106 Federal Blvd, San Diego, CA
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Chula Vista Office Space Available
$4 SF/Yr

Chula Vista Office Space Available

Executive office suite in downtown Chula Vista with private entrance.

237 Church Ave, Chula Vista, CA 91910
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San Diego Office Space Available
$24 SF/Yr
1,000 SF

San Diego Office Space Available

Office space available for lease in San Diego, CA.

1551 Altadena Ave, San Diego, CA
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Renovated Office Space Available
Contact for pricing
2,003 SF

Renovated Office Space Available

Newly renovated office space with flexible floor plans for rent.

303 H St, Chula Vista, CA
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Explore Similar Spaces for Sale in National City, CA

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

National City Mixed-Use Building
$1,385,000
3,538 SF

National City Mixed-Use Building

Mixed-use building in National City with office, retail potential.

921 Coolidge Ave, National City, CA
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National City Retail/Office Space
$1,852,560
4,464 SF

National City Retail/Office Space

Retail and office space with dedicated parking in National City.

801 National City Blvd, National City, CA 91950
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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Fontana Commercial Land Lease
$0.01 SF/Yr
1,565 SF

Prime Fontana Commercial Land Lease

4.33-acre commercial land for ground lease in Fontana, CA.

16203 Foothill Boulevard, Fontana, CA 92335
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Prime Commercial Land for Lease
Contact for pricing
75,000 SF

Prime Commercial Land for Lease

Highly visible 3.59-acre commercial land in San Luis Obispo.

2040 Prado Road, San Luis Obispo, CA 93401
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Chico Commercial Land For Lease
$5,000 /Mo
9,000 SF

Chico Commercial Land For Lease

Prime corner lot in Chico for build to suit.

996 E 1st Avenue, Chico, CA 95926
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Los Ranchos Commercial Land For Rent
$1,000 /Mo

Los Ranchos Commercial Land For Rent

High-traffic commercial land with excellent visibility in Los Ranchos, NM.

6401 4th Street NW, Los Ranchos, NM 87107
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National City, CA Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in National City, CA with 5 listings featured on our commercial real estate exchange. The current inventory includes 1,201,994,640 square feet of properties with an estimated lease value of $0.00 SF/Yr.

Estimated lease rates for Office properties & Spaces in National City, CA begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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