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    Seneca, SC Office Buildings for Sale

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    Commercial Property on Radio Station Rd
    $250,000
    0.63 Acres

    Commercial Property on Radio Station Rd

    11081 N Radio Station Rd, Seneca, SC 29678

    Commercial property with road frontage, suitable for business location.

    • High‑traffic location on Radio Station Rd just outside Seneca city limits.
    • Great road frontage.
    • Suitable for remodeling or new construction.
    • Ideal for commercial property investors or business owners.
    • Existing building is block construction with concrete flooring.
    Updated: Dec 30, 2025
    View details
    Based on your search, we've compiled 125 Potential Opportunities for your consideration. Besides 1 Active listings in Seneca, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 119 Off-Market properties to explore as potential leads, plus 1 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Versatile Property Near AnMed Hospital
    $925,000

    Versatile Property Near AnMed Hospital

    Versatile 4,300 SF property suitable for office or retail.

    1502 E Greenville St, Anderson, SC 29621
    View details
    Downtown Anderson Two-Story Office Building
    $595,000

    Downtown Anderson Two-Story Office Building

    Two-story office building in downtown Anderson with private parking.

    1008 North Main Street Ext, Anderson, SC 29621
    View details
    Easley Office Building For Sale
    Contact for pricing
    7,163 SF

    Easley Office Building For Sale

    Office building on a 0.29-acre lot, suitable for owner-occupant.

    401 E 1St Ave, Easley, SC 29640
    View details
    Multi-Tenant Investment Opportunity
    $550,000

    Multi-Tenant Investment Opportunity

    6,250 SF multi-tenant investment opportunity in Easley, SC.

    1649 East Main St, Easley, SC 29640
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Lot Near Wells Highway
    $395,000
    0.99 Acres

    Commercial Lot Near Wells Highway

    0.99-acre commercial lot with high visibility and easy access.

    Cor Of Wl Hwy. & Return Church Rd. Hwy, Seneca, SC 29678
    View details

    Explore Off-Market Properties in Seneca, SC

    Consider similar Off-Market properties in Seneca, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    280 Seneca Crk Rd

    280 Seneca Crk Rd

    OFFICE BUILDING • 76.00 Acres
    Value Estimation by Request
    280 Seneca Crk Rd, Seneca, SC 29678-1405
    View details
    311 Old Salem Rd

    311 Old Salem Rd

    OFFICE BUILDING • 1,320 SF
    Value Estimation by Request
    311 Old Salem Rd, Seneca, SC 29672-2330
    View details
    1659 Sandifer Blvd

    1659 Sandifer Blvd

    OFFICE BUILDING • 4,540 SF
    Value Estimation
    $565,000
    1659 Sandifer Blvd, Seneca, SC 29678-0906
    View details
    210 Wn 1st St

    210 Wn 1st St

    OFFICE BUILDING • 653 SF
    Value Estimation by Request
    210 Wn 1st St, Seneca, SC 29678-3250
    View details
    10702 Clemson Blvd

    10702 Clemson Blvd

    OFFICE BUILDING • 1,900 SF
    Value Estimation by Request
    10702 Clemson Blvd, Seneca, SC 29678-4528
    View details
    10704 Clemson Blvd, Unit 2

    10704 Clemson Blvd, Unit 2

    OFFICE BUILDING • 1,718 SF
    Value Estimation by Request
    10704 Clemson Blvd, Seneca, SC 29678-4528
    View details
    100 Debra St

    100 Debra St

    OFFICE BUILDING • 3,136 SF
    Value Estimation by Request
    100 Debra St, Seneca, SC 29678-0831
    View details
    114 Wn 1st St

    114 Wn 1st St

    OFFICE BUILDING • 3,264 SF
    Value Estimation by Request
    114 Wn 1st St, Seneca, SC 29678-3248
    View details
    Seneca, SC 29678

    Seneca, SC 29678

    OFFICE BUILDING • 2,400 SF
    Value Estimation by Request
    Seneca, SC 29678
    View details
    Seneca, SC 29672

    Seneca, SC 29672

    OFFICE BUILDING • 9,606 SF
    Value Estimation
    $1,205,000
    Seneca, SC 29672
    View details
    Seneca, SC 29672

    Seneca, SC 29672

    OFFICE BUILDING • 1,040 SF
    Value Estimation by Request
    Seneca, SC 29672
    View details
    104 Wn 1st St

    104 Wn 1st St

    OFFICE BUILDING • 5,400 SF
    Value Estimation by Request
    104 Wn 1st St, Seneca, SC 29678-3248
    View details
    916 En 1st St

    916 En 1st St

    OFFICE BUILDING • 988 SF
    Value Estimation by Request
    916 En 1st St, Seneca, SC 29678-2830
    View details
    10129 Clemson Blvd

    10129 Clemson Blvd

    OFFICE BUILDING • 3,426 SF
    Value Estimation by Request
    10129 Clemson Blvd, Seneca, SC 29678-0818
    View details
    841 Wn 1st St

    841 Wn 1st St

    OFFICE BUILDING • 1,100 SF
    Value Estimation by Request
    841 Wn 1st St, Seneca, SC 29678-2528
    View details
    Seneca, SC 29672

    Seneca, SC 29672

    OFFICE BUILDING • 3,525 SF
    Value Estimation
    $560,000
    Seneca, SC 29672
    View details
    807 By Pass 123rd Ste, Unit 19

    807 By Pass 123rd Ste, Unit 19

    OFFICE BUILDING • 1,320 SF
    Value Estimation by Request
    807 By Pass 123rd Ste, Seneca, SC 29678-4756
    View details
    1743 Blue Rdg Blvd

    1743 Blue Rdg Blvd

    OFFICE BUILDING • 1,920 SF
    Value Estimation by Request
    1743 Blue Rdg Blvd, Seneca, SC 29672-6613
    View details
    807 By Pass 123

    807 By Pass 123

    OFFICE BUILDING • 800 SF
    Value Estimation by Request
    807 By Pass 123, Seneca, SC 29678-4759
    View details
    204 By Pass 123

    204 By Pass 123

    OFFICE BUILDING • 1,353 SF
    Value Estimation by Request
    204 By Pass 123, Seneca, SC 29678-0824
    View details
    10889 Clemson Blvd

    10889 Clemson Blvd

    OFFICE BUILDING • 6,345 SF
    Value Estimation
    $1,120,000
    10889 Clemson Blvd, Seneca, SC 29678-1303
    View details
    10700 Clemson Blvd, Unit 2

    10700 Clemson Blvd, Unit 2

    OFFICE BUILDING • 1,718 SF
    Value Estimation by Request
    10700 Clemson Blvd, Seneca, SC 29678-4528
    View details
    265 Cv Rd

    265 Cv Rd

    OFFICE BUILDING • 2,500 SF
    Value Estimation by Request
    265 Cv Rd, Seneca, SC 29672-6712
    View details

    Seneca, SC Office Buildings Investment Opportunities Market Analysis

    Explore 120 office buildings for sale in Seneca, SC on our real estate platform. These investment opportunities span a total of 3,656,863 square feet of properties for sale, with an estimated market value of $54,545,000.

    Sale prices for office properties in Seneca, SC start at $50,000, averaging $1,948,035, and reaching up to $24,940,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Seneca, SC

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    • 29672

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