San Ysidro, CA Office Buildings for Sale

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Updated: Mar 11

Three-Story Mixed-Use Building

2368 2nd AVE, San Diego, CA 92101

$2,669,000

3,800 sqft 0.13 AC lot

3‑story mixed‑use building with approximately 3,800 square feet
0.1251‑acre parcel at 2368 2nd AVE, San Diego, CA 92101
Independent access to each floor supports separate occupancy or leasing
Mixed‑use zoning accommodates commercial and residential configurations
Mills Act property with tax benefits for qualified owners

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Updated: Apr 29

Freestanding Office Building with Parking

6334 University Avenue, San Diego, CA 92115

$950,000

Freestanding commercial office building built in 1949 currently operating as a mortuary
Functional interior layout includes reception/waiting area, chapel/viewing space, and private offices/meeting rooms
Includes restroom facilities and rear access for operations and customer flow
On‑site parking plus convenient alley access, monument signage, and gated backyard area
Well‑positioned along a highly visible corridor in the Rolando/College Area submarket (buyer to verify zoning/permits)

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Freestanding Office Building

6334 University Ave, San Diego, CA 92115

$950,000

2,273 sqft

Functional office configuration with reception areas, private rooms, monument signage, rear access, and on-site parking.

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See what stands out in San Diego County

We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

We check every listing here. A few are worth a second look.

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Freestanding Office Building

1501 5th Ave, San Diego, CA 92101

$8,500,000

43,670 sqft

Freestanding office asset offering immediate occupancy, customization flexibility, and access to downtown amenities and public transportation.

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Kearny Mesa Multi-Tenant Office Building

4565 Ruffner St, San Diego, CA 92111

$4,750,000

15,974 sqft

Two-story office building near Convoy Street, fully occupied by 27 tenants.

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Corner-Lot Mixed-Use Building

2754 Imperial Avenue, San Diego, CA 92102

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4,272 sqft 0.13 AC lot

Private offices, four restrooms, a kitchenette, and on-site parking accommodate flexible commercial occupancy.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,169 sqft 3.05 AC lot

Four-story medical office building on 3.05 acres along Interstate 15 with two elevators, a landscaped courtyard, and ample parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,267 sqft 3.05 AC lot

Four-story medical office building with recently upgraded systems, two elevators, and structured amenities.

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Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,745 sqft 3.05 AC lot

Four-story medical office building with elevators, landscaped courtyard, conferencing facilities, and ample surface and covered parking.

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Four-Story Medical Office Building with Courtyard

11770 Bernardo Plaza Ct, San Diego, CA 92128

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790 sqft 3.05 AC lot

Steel-frame medical office building with a landscaped courtyard, two elevators, and ample surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,768 sqft 3.05 AC lot

Four-story medical office building with elevators, landscaped courtyard, conferencing facilities, and ample surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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2,676 sqft 3.05 AC lot

Four-story medical office building built in 1984 with elevators, central courtyard, and ample surface and covered parking.

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Medical Office Plaza Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,601 sqft 3.05 AC lot

Four-story medical office building with elevators, central courtyard, and ample surface and covered parking.

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Single-Tenant Mixed-Use Building

2317 Hotel Circle South, San Diego, CA 92108

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9,240 sqft 1.86 AC lot

Two-story retail and office asset with CO-2-2 zoning and on-site parking.

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Class A Office Tower with Bay Views

610 W Ash St, San Diego, CA 92101

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189,242 sqft

Nineteen-story downtown property with government occupancy, upper-floor vacancy, and building-top signage.

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Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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1,481 sqft 3.05 AC lot

Four-story medical office building with elevators, central courtyard, and ample surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

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859 sqft 3.05 AC lot

Recently upgraded medical office property with elevators, conferencing facilities, showers, lockers, and surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

Contact for pricing

3,348 sqft 3.05 AC lot

Four-story medical office with two elevators, landscaped courtyard, conferencing facilities, and ample surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

Contact for pricing

1,165 sqft 3.05 AC lot

Recently upgraded medical office space with elevators, conferencing facilities, showers, lockers, and surface and covered parking.

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Four-Story Medical Office Building

11770 Bernardo Plaza Ct, San Diego, CA 92128

Contact for pricing

1,529 sqft 3.05 AC lot

Steel-frame medical office property with elevators, conferencing facilities, showers, lockers, and surface and covered parking.

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Three-Story Corporate Office Building

5855 Copley Drive, San Diego, CA 92111

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120,483 sqft 5.31 AC lot

Three-story office building with efficient floor plates and an adjacent four-level parking structure.

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Office Building

5620 Friars Road, San Diego, CA 92110

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55,196 sqft

Office property with CO-1-2 zoning and direct access to the I-8 freeway corridor.

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Turnkey Creative Office Building

5186 Carroll Canyon Rd, San Diego, CA 92121

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10,000 sqft

Fully renovated single-tenant office building with open collaboration areas, private offices, and abundant natural light.

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Office Building with Parking

4470 Park Boulevard, San Diego, CA 92116

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14,594 sqft

Flexible office property with CN-1-4 zoning and on-site surface parking in a walkable urban neighborhood.

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San Ysidro, CA Office Buildings Market Trends and Statistics

Explore 80 office buildings for sale in San Ysidro, CA, showcased through 80 active listings on our real estate platform. These investment opportunities span a total of 1,366,896 square feet of properties for sale, with an estimated market value of $24,823,000.

Sale prices for office properties in San Ysidro, CA start at $699,000, averaging $3,102,875, and reaching up to $8,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 27K

Population Growth (5Y) -16.8%

Median Household Income $65,865

College Educated 7.2%

Taxes & Financing

Tax Rate (average for all types) 0.94%

Property Tax per SF $14.23 per SF

Tax Rate vs County Average 0.24 pp below county avg

Average Loan-to-Value 65.0%

Listings Trend

New vs delisted commercial listings in San Diego County

New Delisted

Total CRE Inventory on Market (SF)

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