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    South Carolina Office Buildings for Lease

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    Greenville, SC Columbia, SC Charleston, SC
    Showing 24 of 168 results
    Downtown Class A Office Building
    $38 SF/Yr
    10,708 SF
    Downtown Class A Office Building

    Class A office building with attached parking garage in downtown.

    300 N Main Street, Greenville, SC 29601

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    Available Office Building in Greenville
    Contact for pricing
    124,836 SF
    Available Office Building in Greenville

    124,836 SF office building for rent near I-85.

    50 Datastream Plaza, Greenville, SC 29605

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    Historic Downtown Greenville Office Space
    $28 SF/Yr
    2,150 SF
    Historic Downtown Greenville Office Space

    Historic office building in downtown Greenville with modern amenities.

    130 S Main St, Greenville, SC

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    Class A Office Space Available
    Contact for pricing
    8,650 SF
    Class A Office Space Available

    Class A office building with utilities included, available 8/1/2018.

    1069 Bayshore Dr, Rock Hill, SC 29732

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    Renovated Office Building in CBD
    Contact for pricing
    1,960 SF
    Renovated Office Building in CBD

    Freestanding, renovated office building in Columbia's Central Business District.

    1830 Sumter St, Columbia, SC 29201

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    Downtown Columbia Boutique Office Space
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    Downtown Columbia Boutique Office Space

    Second floor office space for lease in downtown Columbia.

    1527 Blanding St, Columbia, SC 29201

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    Class A Street-Front Retail Opportunity
    Contact for pricing
    12,640 SF
    Class A Street-Front Retail Opportunity

    Ground-floor retail at a Robert A.M. Stern-designed mixed-use address with sub-dividable space and build-to-suit potential.

    465 Meeting Street, Charleston, SC 29403

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    334,000 SF Office Building For Lease
    $19 SF/Yr
    334,000 SF Office Building For Lease

    334,000 SF Office Building For Lease

    300 South St, Simpsonville, SC 29681

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    Greenville Office Space Available
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    131,382 SF
    Greenville Office Space Available

    Office building with 131,382 square feet available for rent.

    1041 E Butler Rd, Greenville, SC 29607

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    Ebenezer Road Office Building
    Contact for pricing
    1,658 SF
    Ebenezer Road Office Building

    Office building near Winthrop University and regional hospital for rent.

    1220 Ebenezer Rd, Rock Hill, SC 29732

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    Two-Story Office Building Available
    Contact for pricing
    5,500 SF
    Two-Story Office Building Available

    Two-story office building with ample parking and multiple access points.

    501 Roper Mountain Rd, Greenville, SC

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    Renovated Office Building, High Visibility
    Contact for pricing
    35,500 SF
    Renovated Office Building, High Visibility

    Office building with recent renovations and high interstate visibility.

    1001 Keys Drive, Greenville, SC 29615

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    Freestanding Single Tenant Office Building
    Contact for pricing
    Freestanding Single Tenant Office Building

    Single tenant office building with multiple offices and storage.

    260 S Pleasantburg Dr, Greenville, SC 29607

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    Historic French Quarter Office Space
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    Historic French Quarter Office Space

    Charming 2,400 SF office in Charleston's French Quarter.

    46A State Street & 15 Lodge Alley, Charleston, SC 29401

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    Trophy Office Space Sublease
    Contact for pricing
    36,450 SF
    Trophy Office Space Sublease

    Sublease opportunity: Furnished office space with amenities and parking.

    215 Benefitfocus Way #1st Floor, Charleston, SC 29492

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    Renovated Class A Office Building
    $32 SF/Yr
    Renovated Class A Office Building

    Three-story office building with high-end finishes, available April 2026.

    4055 Faber Place Drive # 104, North Charleston, SC 29405

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    Class A Office Space
    $39 SF/Yr
    3,770 SF
    Class A Office Space

    Class A office building in West Ashley with convenient access.

    176 Croghan Spur Rd, Charleston, SC

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    Class A Office Building
    $33 SF/Yr
    34,765 SF
    Class A Office Building

    Modern office building in the heart of West Ashley.

    1014 St Andrews Blvd, Charleston, SC 29407

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    Standalone Office Building in Columbia
    Contact for pricing
    5,000 SF
    Standalone Office Building in Columbia

    Two-story office building with parking and storage for lease.

    1430 Blanding St, Columbia, SC 29201

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    Freestanding Office Building in Myrtle Beach
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    Freestanding Office Building in Myrtle Beach

    Office building in The Market Common District for rent.

    1051 Shine Ave, Myrtle Beach, SC 29577

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    Industrial Outdoor Storage with Office
    $15 SF/Yr
    Industrial Outdoor Storage with Office

    10 acre industrial site with 7,040 SF office.

    625 Five Chop Rd, Orangeburg, SC

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    Greenville Office Building For Rent
    $23 SF/Yr
    7,877 SF
    Greenville Office Building For Rent

    46,047 SF office building in Greenville, South Carolina.

    250 Commonwealth Drive, Greenville, SC

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    Daniel Island Office Sublease Opportunity
    Contact for pricing
    Daniel Island Office Sublease Opportunity

    Sublease opportunity in Blackbaud's Daniel Island headquarters.

    65 Fairchild St, Charleston, SC 29492

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    Multi-Tenant Office Building For Rent
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    Multi-Tenant Office Building For Rent

    Three-story office building in the Devine Street corridor.

    2231 Devine Street, Columbia, SC 29205

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