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    Two-Story Flex Space with Elevator
    Updated: Apr 16
    Two-Story Flex Space with Elevator

    453-467 Forbes Boulevard, South San Francisco, CA 94080

    Contact for pricing
    3,786 sqft
    Warehouse area of 119,798 SF
    22–24’ clear height
    Two‑story building with elevator
    New office buildout with high‑end finishes
    Renovated lobby and common areas
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    Laboratory Office Building
    Updated: Jul 24
    Laboratory Office Building

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    65,764 sqft
    Fully integrated biology, tissue culture, chemistry, and vivarium lab facility
    1st‑floor lab space totals 130,000 SF: Suite A (13,000 SF), Suite B (10,000 SF), and vivarium (7,000 SF)
    2nd‑floor space totals 32,000 SF, with availability starting July 2026
    Full building is available July 2026
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    Office Space Walking Distance to Caltrain
    Office Space Walking Distance to Caltrain

    South San Francisco, CA 94080

    Contact for pricing
    5,283 sqft

    Office space in the South San Francisco life science cluster with convenient Highway 101 access and walkable CalTrain access.

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    Centrally Located Office Building
    Centrally Located Office Building

    South San Francisco, CA 94080

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    9,655 sqft

    Office building in the South San Francisco life science cluster with walking access to CalTrain and nearby Highway 101 access.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    601 Gateway Blvd, South San Francisco, CA 94080

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    10,451 sqft

    Centrally located office space in the South San Francisco life science cluster near CalTrain and Highway 101 access.

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    Office Space Near CalTrain
    Office Space Near CalTrain

    South San Francisco, CA 94080

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    14,168 sqft

    Office space in the South San Francisco Life Science cluster with walking access to CalTrain and convenient Highway 101 access.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    South San Francisco, CA 94080

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    7,107 sqft

    Centrally located office option within the South San Francisco life science cluster, walkable to CalTrain.

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    Office Space Near Caltrain
    Office Space Near Caltrain

    601 Gateway Blvd, South San Francisco, CA 94080

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    2,801 sqft

    Office space in the South San Francisco life science cluster with CalTrain access and nearby retail, dining, and hotels.

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    Office Space in South San Francisco
    Office Space in South San Francisco

    2 Tower Pl, South San Francisco, CA 94080

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    19,986 sqft

    58,446 SF office space available for lease.

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    South San Francisco Office Space
    South San Francisco Office Space

    1487 Huntington Ave, South San Francisco, CA 94080

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    14,000 sqft

    14,000 sqft office space available for rent.

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    Office Space for Lease
    Office Space for Lease

    343 Oyster Point Blvd, South San Francisco, CA 94080

    Contact for pricing
    17,507 sqft

    Office space is available for lease at 343 Oyster Point Blvd with suite sizes ranging from 4,511 to 17,507 SF.

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    South San Francisco Office Space
    South San Francisco Office Space

    453-467 Forbes Blvd, South San Francisco, CA 94080

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    40,606 sqft

    Office building with 40,606 square feet available for rent.

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    Integrated Lab Office Facility
    Integrated Lab Office Facility

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    13,000 sqft

    Fully integrated biology, tissue culture, chemistry, and vivarium lab space across two floors, available July 2026.

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    South San Francisco Life Science Building
    South San Francisco Life Science Building

    901 Gateway Boulevard, South San Francisco, CA 94080

    Contact for pricing
    10,913 sqft

    Three-story life science building for sublease in South San Francisco.

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    South San Francisco Life Science Campus
    South San Francisco Life Science Campus

    East Grand Ave & Harbor Way, South San Francisco, CA 94080

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    226,763 sqft

    Class A life science campus in South San Francisco.

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    Class A Office Building
    Class A Office Building

    6000 Shoreline Court, South San Francisco, CA 94080

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    31,852 sqft

    Class A office building in South San Francisco life science market.

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    Multi-Suite Office Space
    Multi-Suite Office Space

    South San Francisco, CA 94080

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    For-rent office suites offered in configurations spanning suites 200, 400, and 500.

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    Flex Space with Lab and Tissue Culture Suites
    Flex Space with Lab and Tissue Culture Suites

    2 Tower Pl, South San Francisco, CA 94080

    Contact for pricing
    19,986 sqft

    Flex space with existing lab/office areas, mostly open biology space, and tissue culture suites.

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    Lab-Enabled Office Suite with Chemical Hood
    Lab-Enabled Office Suite with Chemical Hood

    5000 Shoreline Court, South San Francisco, CA 94080

    Contact for pricing
    25,977 sqft

    Lab support office space with tissue culture suites, private offices, open area, and an 8-foot chemical hood.

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    Research Laboratory Office Building
    Research Laboratory Office Building

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    7,000 sqft

    Fully integrated biology, tissue culture, chemistry, and vivarium lab facility with space available starting July 2026.

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    Biology Lab Office Suite
    Biology Lab Office Suite

    5000 Shoreline Court, South San Francisco, CA 94080

    Contact for pricing
    21,103 sqft

    Laboratory office suite with tissue culture support and private offices, plus 8-foot chemical hoods and collaborative rooms.

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    South San Francisco Life Science Building
    South San Francisco Life Science Building

    One & Two Tower Place, South San Francisco, CA 94080

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    204,178 sqft

    Class A life science building in prime South San Francisco location.

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    Class A Lab Facility
    Class A Lab Facility

    Veterans Blvd & Oyster Point Blvd, South San Francisco, CA 94080

    Contact for pricing
    96,890 sqft

    Class A lab facility with significant laboratory infrastructure.

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    Based on your search, we've compiled 23 Potential Opportunities for your consideration.

    South San Francisco, CA Office buildings Lease Rates & Market Statistics

    Browse 23 Office buildings for lease in South San Francisco, CA on Realmo, a commercial real estate marketplace serving the South San Francisco area. The current inventory totals 868,776 square feet of properties — an average of ~37,750 SF per listing.

    South San Francisco accounts for 5% of the 459 office buildings currently available across San Mateo County, where nearby markets include San Francisco and San Mateo. Office buildings make up 37% of the 62 Office Spaces currently for lease in South San Francisco. Also worth a look for tenants weighing alternatives: Office Units (34 listings) and Other office properties (3 listings) elsewhere in the South San Francisco market.

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