Advertise
    Location, space use, price
    Office Building

    South San Francisco, CA Office Buildings for Lease

    Notify Me
    List
    Map
    San Francisco, CA Belmont, CA San Bruno, CA Brisbane, CA Daly City, CA Millbrae, CA Burlingame, CA Pacifica, CA
    13 properties
    Sort:
    Laboratory Office Building
    Updated: Jul 24
    Laboratory Office Building

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    65,764 sqft
    Fully integrated biology, tissue culture, chemistry, and vivarium lab facility
    1st‑floor lab space totals 130,000 SF: Suite A (13,000 SF), Suite B (10,000 SF), and vivarium (7,000 SF)
    2nd‑floor space totals 32,000 SF, with availability starting July 2026
    Full building is available July 2026
    View details
    Partially Built-Out Office and Flex Space
    Updated: Jun 7
    Partially Built-Out Office and Flex Space

    1 Tower Place, South San Francisco, CA 94080

    Contact for pricing
    18,748 sqft
    For lease with approximately 50% of the office area already built out, supporting a range of business layouts.
    View details
    South San Francisco Office Space
    South San Francisco Office Space

    1487 Huntington Ave, South San Francisco, CA 94080

    Contact for pricing
    14,000 sqft

    14,000 sqft office space available for rent.

    View details
    Office Space in South San Francisco
    Office Space in South San Francisco

    2 Tower Place, South San Francisco, CA 94080

    Contact for pricing
    19,817 sqft

    58,446 SF office space available for lease.

    View details
    South San Francisco Life Science Building
    South San Francisco Life Science Building

    901 Gateway Boulevard, South San Francisco, CA 94080

    Contact for pricing
    10,913 sqft

    Three-story life science building for sublease in South San Francisco.

    View details
    South San Francisco Office Space
    South San Francisco Office Space

    453-467 Forbes Blvd, South San Francisco, CA 94080

    Contact for pricing
    40,606 sqft

    Office building with 40,606 square feet available for rent.

    View details
    Integrated Lab Office Facility
    Integrated Lab Office Facility

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    13,000 sqft

    Fully integrated biology, tissue culture, chemistry, and vivarium lab space across two floors, available July 2026.

    View details
    South San Francisco Life Science Campus
    South San Francisco Life Science Campus

    East Grand Ave & Harbor Way, South San Francisco, CA 94080

    Contact for pricing
    226,763 sqft

    Class A life science campus in South San Francisco.

    View details
    Class A Office Building
    Class A Office Building

    6000 Shoreline Court, South San Francisco, CA 94080

    Contact for pricing
    31,852 sqft

    Class A office building in South San Francisco life science market.

    View details
    Research Laboratory Office Building
    Research Laboratory Office Building

    285 E Grand Ave, South San Francisco, CA 94080

    Contact for pricing
    7,000 sqft

    Fully integrated biology, tissue culture, chemistry, and vivarium lab facility with space available starting July 2026.

    View details
    Flex Space with Lab and Tissue Culture Suites
    Flex Space with Lab and Tissue Culture Suites

    2 Tower Pl, South San Francisco, CA 94080

    Contact for pricing
    19,986 sqft

    Flex space with existing lab/office areas, mostly open biology space, and tissue culture suites.

    View details
    South San Francisco Life Science Building
    South San Francisco Life Science Building

    One & Two Tower Place, South San Francisco, CA 94080

    Contact for pricing
    212,379 sqft

    Class A life science building in prime South San Francisco location.

    View details
    Class A Lab Facility
    Class A Lab Facility

    Veterans Blvd & Oyster Point Blvd, South San Francisco, CA 94080

    Contact for pricing
    96,890 sqft

    Class A lab facility with significant laboratory infrastructure.

    View details
    Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 13 Active listings in South San Francisco, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities

    Office buildings for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Class A Office Campus
    Class A Office Campus

    2000 Sierra Point Parkway, Brisbane, CA 94005

    Contact for pricing
    20,116 sqft

    Two-building Class A office campus with prominent freeway visibility and Bay-facing views, featuring an on-site amenity package.

    View details
    Office Building for Lab Sublease
    Office Building for Lab Sublease

    1200 Sierra Point Pkwy, Brisbane, CA 94005

    Contact for pricing
    34,465 sqft

    Building E offers available office and lab space for sublease, with sizes ranging from 23,166 to 92,096 SF.

    View details
    Two Class A Office Buildings
    Two Class A Office Buildings

    851 Traeger Ave, San Bruno, CA 94066

    Contact for pricing
    7,450 sqft

    Two Class A office buildings on landscaped grounds with on-site management and recent improvements.

    View details
    Office Suite with Workstations
    Office Suite with Workstations

    851 Traeger Ave, San Bruno, CA 94066

    Contact for pricing
    6,026 sqft

    Well-equipped office space with reception, multiple conference rooms, private offices, kitchen, and about 90 workstations.

    View details

    South San Francisco, CA Office buildings Lease Rates & Market Statistics

    Browse 13 Office buildings for lease in South San Francisco, CA on Realmo, a commercial real estate marketplace serving the South San Francisco area. The current inventory totals 777,718 square feet of properties — an average of ~59,800 SF per listing.

    South San Francisco accounts for 4% of the 348 office buildings currently available across San Mateo County, where nearby markets include San Francisco and San Mateo. Office buildings make up 27% of the 48 Office Spaces currently for lease in South San Francisco. Also worth a look for tenants weighing alternatives: Office Units (30 listings) and Other office properties (3 listings) elsewhere in the South San Francisco market.

    List
    Map

    Popular Searches in South San Francisco, CA

    Popular Categories

    Most Searched ZIP Codes in South San Francisco, CA

    • 94080
    Why this one?
    Saved

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!