Office Building

Irvine, CA Office Buildings for Lease

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Office Building for Lease
Updated: Jun 17, 2025
Office Building for Lease

2020 Main Street, Irvine, CA 92614

$4,593/Mo
Central air conditioning
Year built: 1999
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Single-Story Medical Office Building
Updated: Jul 15
Single-Story Medical Office Building

70 Discovery, Irvine, CA 92618

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5,846 sqft
Single‑story freestanding office building built in 2004 with ±5,846 SF in the Barranca Business Center
Medical and Science (5.5‑A) zoning with flexible interior layout including private offices, conference rooms, and lab area
Five (5) private offices with floor‑to‑ceiling glass plus two (2) conference rooms
Dedicated lab area (convertible back to office), server room, and storage room
Polished concrete floors throughout and extensive interior/exterior glass line
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Class A Three-Story Office Building
Class A Three-Story Office Building

17900 Von Karman Avenue, Irvine, CA 92614

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71,864 sqft

Surface parking supports a three-level workplace in Irvine’s master planned business district.

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Freestanding Single-Story Retail Facility
Freestanding Single-Story Retail Facility

17361 Armstrong Ave, Irvine, CA 92614

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11,331 sqft

Freestanding single-story retail facility with a 4:1 parking ratio available for lease in Irvine.

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Two-Story Medical Office Building
Two-Story Medical Office Building

15751 Rockfield Boulevard, Irvine, CA 92618

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13,140 sqft

Community Commercial zoning supports medical and general office use.

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Office Building for Lease
Office Building for Lease

8 Hughes, Irvine, CA 92618

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9,790 sqft

For lease office building totaling 9,790 square feet at 8 Hughes in Irvine, CA 92618.

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Creative Office Space
Creative Office Space

9927-9931 Muirlands Blvd, Irvine, CA 92618

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7,463 sqft

Open-plan workspace with perimeter offices, private restrooms, conference facilities, and direct parking-lot access.

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Office Building with Black Glass Façade
Office Building with Black Glass Façade

18200 Von Karman Ave., Irvine, CA 92612

$37.80 SF/Yr

Eleven-story office building with steel-reinforced concrete frame and black glass exterior in Irvine.

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Premier Office Space in Irvine
Premier Office Space in Irvine

3121 Michelson Drive, Irvine, CA 92612

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65,145 sqft 105.00 AC lot

175,000 SF of divisible premier office space for lease.

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Office Space in Shell Condition
Office Space in Shell Condition

19000 MacArthur Blvd., Irvine, CA 92612

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44,813 sqft

Office space offered in shell condition for tenant customization.

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Class A Office Building
Class A Office Building

3161 Michelson Drive, Irvine, CA 92612

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99,662 sqft

19-story office building with immediate freeway access.

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Irvine Office Campus For Lease
Irvine Office Campus For Lease

4000-4050 Barranca Parkway, Irvine, CA 92604

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158,000 sqft

Four-building office campus in Irvine with on-site amenities.

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Four-Building Office Campus
Four-Building Office Campus

4050 Barranca Parkway, Irvine, CA 92604

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Suburban office complex with restaurants, landscaped shared areas, and on-site management.

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Renovated Office Building in Irvine
Renovated Office Building in Irvine

2151 Michelson Drive, Irvine, CA 92612

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18,145 sqft

Recently renovated 93,000 SF office building near John Wayne Airport.

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Class A Office Building
Class A Office Building

5 Peters Canyon Road, Irvine, CA 92606

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26,781 sqft

157,279 SF office building near transportation and retail.

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Class A Office Space
Class A Office Space

2201 Dupont Drive, Irvine, CA 92612

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25,077 sqft

250,000 SF Class A office in Irvine, CA.

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Freestanding Office/Flex Building
Freestanding Office/Flex Building

15253 Bake Pkwy, Irvine, CA 92618

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65,006 sqft 4.50 AC lot

Freestanding office/flex building with dock-high access, freight elevator service, and an on-site kitchen and cafeteria.

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Two-Story Office Building with ESFR
Two-Story Office Building with ESFR

15800 Bake Pkwy, Irvine, CA 92618

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202,831 sqft

Free-standing two-story office building offering 18,168 SF with an ESFR sprinkler system and freeway signage.

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Class A Office Building
Class A Office Building

1900 Main Street, Irvine, CA 92614

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67,392 sqft

High-rise office building in Irvine Concourse available for rent.

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Parker Irvine Freestanding Building
Parker Irvine Freestanding Building

2 Musick, Irvine, CA

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96,000 sqft 12.42 AC lot

Sublease available in Parker Irvine Business Center through 2028.

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Office Building For Rent
Office Building For Rent

17732 Cowan, Irvine, CA 37318

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Office property offered for rent at a Cowan address in Irvine.

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Office Building for Lease
Office Building for Lease

2505 McCabe Way, Irvine, CA 92614

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Office building available for lease at 2505 McCabe Way in Irvine, CA 92614.

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Class A Office Building, Irvine
Class A Office Building, Irvine

2030 Main St, Irvine, CA 92614

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16-story Class A office building in the heart of Irvine.

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Office Space for Lease
Office Space for Lease

4000 Barranca Pkwy, Irvine, CA 92604

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Office space available for lease at 4000 Barranca Pkwy in Irvine, CA.

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Irvine, CA Office buildings Lease Rates & Market Statistics

Browse 39 Office buildings for lease in Irvine, CA on Realmo, a commercial real estate marketplace serving the Irvine area. The current inventory totals 1,789,158 square feet of properties — an average of ~45,900 SF per listing.

Office buildings lease rates in Irvine range from $37.80 SF/Yr at the entry level to $37.80 SF/Yr at the top of the market, averaging $37.80 SF/Yr. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $37.80 SF/Yr, the local average runs 56% above California's state average of $24.18 SF/Yr.

Irvine accounts for 21% of the 185 office buildings currently available across Orange County, where nearby markets include Newport Beach and Santa Ana. Office buildings make up 21% of the 190 Office Spaces currently for lease in Irvine, with asking rates averaging $37.80 SF/Yr — 11% below the citywide Office Spaces average of $42.36 SF/Yr. Tenants comparing options may also consider Office Units (130 listings) and Coworking space (14 listings) elsewhere in the Irvine market.

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