Sign Up Successful!
You now have access to more from Realmo!
    For Sale
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Mixed-Use
    1
    • Retail
    • Office
    • Residential Income
    • Restaurants
    • Industrial
    • Mixed-Use
    • Hospitality
    • Health Care
    • Sports & Entertainment
    • Land
    • Agricultural
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Roanoke, VA Mixed-use Properties for Sale

    Notify Me
    List
    Map
    Downtown Roanoke Investment Opportunity
    $875,000
    0.05 Acres

    Downtown Roanoke Investment Opportunity

    22 Campbell Ave SE, Roanoke, VA 24011

    Two-unit building in vibrant downtown Roanoke with retail and residential.

    • Prime Downtown Roanoke location offering high visibility and accessibility.
    • Two‑unit building with commercial and residential income potential.
    • First floor retail space leased through March 31, 2030.
    • Modern, renovated 2bd/2bth residential unit on the second floor (available February 1, 2026).
    • High‑end finishes including recessed lighting, granite, and hardwoods.
    Updated: Nov 17, 2025
    View details
    Green Ridge Center: Roanoke, VA
    $1,649,000
    13,908 SF

    Green Ridge Center: Roanoke, VA

    2350 Peters Creek Rd, Roanoke, VA 24017

    Mixed-use center, high visibility, strong tenants.

    • Excellent visibility on Peters Creek Road, a major thoroughfare.
    • Median crossover provides convenient access.
    • New roof installed in 2018.
    • Multiple long‑term tenants.
    • 3,526 square feet of contiguous space available for owner‑occupant or new tenant.
    Updated: Dec 11, 2024
    View details
    Based on your search, we've compiled 2701 Potential Opportunities for your consideration. Besides 2 Active listings in Roanoke, VA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2695 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Lakefront Medical Office Opportunity
    $1,250,000
    3,200 SF

    Lakefront Medical Office Opportunity

    Smith Mountain Lake medical office building

    1027 Waterwheel Dr, Moneta, VA 24121
    View details
    Moneta Land with Mixed-Use Zoning
    $2,499,000
    60.60 Acres

    Moneta Land with Mixed-Use Zoning

    60.6 acres in Eastlake area with high visibility.

    15093 Moneta Rd, Moneta, VA 24121
    View details
    Christiansburg Commercial Land Development
    Contact for pricing

    Christiansburg Commercial Land Development

    15.6 Acres, I-81 Exit, High Traffic

    0 Roanoke St, Christiansburg, VA 24073
    View details
    Prime Redevelopment Opportunity in Christiansburg
    $2,000,000
    0.97 Acres

    Prime Redevelopment Opportunity in Christiansburg

    Redevelopment opportunity in active commercial corridor near major thoroughfares.

    2405 Market St, Christiansburg, VA 24073
    View details

    Explore Off-Market Properties in Roanoke, VA

    Consider similar Off-Market properties in Roanoke, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3151 Williamson NW Rd

    3151 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,944 SF
    Value Estimation
    $315,000
    3151 Williamson NW Rd, Roanoke, VA 24012-4315
    View details
    510 Jefferson St

    510 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 152,460 SF
    Value Estimation
    $255,000
    510 Jefferson St, Roanoke, VA 24011
    View details
    202 2nd NE St

    202 2nd NE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,100 SF
    Value Estimation
    $305,000
    202 2nd NE St, Roanoke, VA 24016-2099
    View details
    1004 Gus W Nicks NE Blvd

    1004 Gus W Nicks NE Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,487 SF
    Value Estimation
    $400,000
    1004 Gus W Nicks NE Blvd, Roanoke, VA 24012-6246
    View details
    736 Pearl NE Ave

    736 Pearl NE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 10,800 SF
    Value Estimation
    $335,000
    736 Pearl NE Ave, Roanoke, VA 24012-7515
    View details
    214 5th SW St

    214 5th SW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,100 SF
    Value Estimation
    $320,000
    214 5th SW St, Roanoke, VA 24016
    View details
    2620 Railroad SW Ave

    2620 Railroad SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,200 SF
    Value Estimation
    $320,000
    2620 Railroad SW Ave, Roanoke, VA 24015
    View details
    208 12th SE St

    208 12th SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.52 Acres
    Value Estimation
    $70,000
    208 12th SE St, Roanoke, VA 24013-1110
    View details
    941 Industry SE Ave

    941 Industry SE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 214,884 SF
    Value Estimation
    $9,875,000
    941 Industry SE Ave, Roanoke, VA 24013-2927
    View details
    3201 Williamson NW Rd

    3201 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,658 SF
    Value Estimation
    $475,000
    3201 Williamson NW Rd, Roanoke, VA 24012-4317
    View details
    302 Jefferson St

    302 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 28,626 SF
    Value Estimation
    $760,000
    302 Jefferson St, Roanoke, VA 24011-1711
    View details
    2519 Johnson NW Ave

    2519 Johnson NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,540 SF
    Value Estimation
    $315,000
    2519 Johnson NW Ave, Roanoke, VA 24017
    View details
    3641 Blue Hls Vlg NE Dr

    3641 Blue Hls Vlg NE Dr

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.50 Acres
    Value Estimation
    $3,015,000
    3641 Blue Hls Vlg NE Dr, Roanoke, VA 24012-8615
    View details
    630 Bedford SW St

    630 Bedford SW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,000 SF
    Value Estimation
    $315,000
    630 Bedford SW St, Roanoke, VA 24015
    View details
    1003 Jefferson St

    1003 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,502 SF
    Value Estimation
    $320,000
    1003 Jefferson St, Roanoke, VA 24016-4405
    View details
    3 12th St SE St

    3 12th St SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,696 SF
    Value Estimation
    $235,000
    3 12th St SE St, Roanoke, VA 24013
    View details
    1122 Country Clb NW Dr

    1122 Country Clb NW Dr

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 24,145 SF
    Value Estimation
    $880,000
    1122 Country Clb NW Dr, Roanoke, VA 24017
    View details
    1452 Towne Sq NW Blvd

    1452 Towne Sq NW Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 7,191 SF
    Value Estimation
    $440,000
    1452 Towne Sq NW Blvd, Roanoke, VA 24012
    View details
    513 Salem SW Ave

    513 Salem SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 15,796 SF
    Value Estimation
    $940,000
    513 Salem SW Ave, Roanoke, VA 24016
    View details
    3215 Williamson NW Rd

    3215 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 13,032 SF
    Value Estimation
    $360,000
    3215 Williamson NW Rd, Roanoke, VA 24012-4317
    View details
    2201 Railroad SW Ave

    2201 Railroad SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 22,960 SF
    Value Estimation
    $415,000
    2201 Railroad SW Ave, Roanoke, VA 24015-4803
    View details
    3 Riverside Cir

    3 Riverside Cir

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 186,725 SF
    Value Estimation
    $860,000
    3 Riverside Cir, Roanoke, VA 24016-4955
    View details

    Roanoke, VA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2696 mixed-use properties for sale in Roanoke, VA on our real estate platform. These investment opportunities span a total of 77,161,841 square feet of properties for sale, with an estimated market value of $1,103,099,000.

    Prices for multi use buildings in Roanoke, VA start at $50,000, averaging $637,261, and reaching up to $12,815,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

    List
    Map

    Popular Searches in Roanoke, VA

    Popular Categories

    Most Searched ZIP Codes in Roanoke, VA

    • 24011
    • 24014
    • 24017
    • 24012
    • 24016
    • 24015
    • 24013
    • 24018
    • 24019

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Create New Password
    • At least 8 characters
    • Contains both letters and numbers
    • Contains uppercase and lowercase letters
    • At most 32 characters
    • Password required
    • Password reset link has expired. Please request a new one.