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    Roanoke, VA Mixed-use Properties for Sale

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    Downtown Roanoke Investment Opportunity
    $875,000
    0.05 Acres

    Downtown Roanoke Investment Opportunity

    22 Campbell Ave SE, Roanoke, VA 24011

    Two-unit building in vibrant downtown Roanoke with retail and residential.

    • Prime Downtown Roanoke location offering high visibility and accessibility.
    • Two‑unit building with commercial and residential income potential.
    • First floor retail space leased through March 31, 2030.
    • Modern, renovated 2bd/2bth residential unit on the second floor (available February 1, 2026).
    • High‑end finishes including recessed lighting, granite, and hardwoods.
    Last Update: Nov 17
    View details
    Green Ridge Center: Roanoke, VA
    $1,649,000
    13,908 SF

    Green Ridge Center: Roanoke, VA

    2350 Peters Creek Rd, Roanoke, VA 24017

    Mixed-use center, high visibility, strong tenants.

    • Excellent visibility on Peters Creek Road, a major thoroughfare.
    • Median crossover provides convenient access.
    • New roof installed in 2018.
    • Multiple long‑term tenants.
    • 3,526 square feet of contiguous space available for owner‑occupant or new tenant.
    Last Update: Dec 11, 2024
    View details
    Based on your search, we've compiled 2704 Potential Opportunities for your consideration. Besides 2 Active listings in Roanoke, VA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2695 Off-Market properties to explore as potential leads, plus 3 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Lakefront Medical Office Opportunity
    $1,250,000
    3,200 SF

    Lakefront Medical Office Opportunity

    Smith Mountain Lake medical office building
    1027 Waterwheel Dr, Moneta, VA 24121
    View details
    Lakefront Marina & Restaurant Business
    $3,500,000
    98,000 SF

    Lakefront Marina & Restaurant Business

    Profitable turnkey marina on Smith Mountain Lake.
    3619 Airport Rd, Moneta, VA 24121
    View details
    Adaptable Mixed-Use Development Opportunity
    $7,850,000
    56,044 SF

    Adaptable Mixed-Use Development Opportunity

    2.56-acre parcel near Virginia Tech suitable for mixed-use redevelopment.
    700 University City Blvd, Blacksburg, VA 24060
    View details
    Expansive Land Parcel in Blacksburg
    $8,774,900
    135.00 Acres

    Expansive Land Parcel in Blacksburg

    135+ acre parcel ideal for multifamily or mixed-use development.
    1801 Toms Creek Rd, Blacksburg, VA 24060
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Roanoke Land Ready to Build
    Contact for pricing
    0.11 Acres

    Roanoke Land Ready to Build

    Premium lot near downtown Roanoke with water and sewer access.
    Church Ave SE, Roanoke, VA 24013
    View details
    Roanoke City Lot For Sale
    Contact for pricing
    0.10 Acres

    Roanoke City Lot For Sale

    Residential lot in Southeast Roanoke City, conveniently located near downtown.
    630 Tazewell Ave SE, Roanoke, VA 24013
    View details
    Roanoke City Lot For Sale
    Contact for pricing
    0.10 Acres

    Roanoke City Lot For Sale

    Located in Southeast Roanoke City, zoned MX.
    634 Tazewell Ave SE, Roanoke, VA 24013
    View details

    Explore Off-Market Properties in Roanoke, VA

    Consider similar Off-Market properties in Roanoke, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    3151 Williamson NW Rd

    3151 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 1,944 SF
    Value Estimation
    $340,000
    3151 Williamson NW Rd, Roanoke, VA 24012-4315
    View details
    510 Jefferson St

    510 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 152,460 SF
    Value Estimation by Request
    510 Jefferson St, Roanoke, VA 24011
    View details
    202 2nd NE St

    202 2nd NE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,100 SF
    Value Estimation by Request
    202 2nd NE St, Roanoke, VA 24016-2099
    View details
    1004 Gus W Nicks NE Blvd

    1004 Gus W Nicks NE Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 6,487 SF
    Value Estimation
    $325,000
    1004 Gus W Nicks NE Blvd, Roanoke, VA 24012-6246
    View details
    736 Pearl NE Ave

    736 Pearl NE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 10,800 SF
    Value Estimation
    $400,000
    736 Pearl NE Ave, Roanoke, VA 24012-7515
    View details
    214 5th SW St

    214 5th SW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,100 SF
    Value Estimation
    $390,000
    214 5th SW St, Roanoke, VA 24016
    View details
    2620 Railroad SW Ave

    2620 Railroad SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 3,200 SF
    Value Estimation
    $400,000
    2620 Railroad SW Ave, Roanoke, VA 24015
    View details
    208 12th SE St

    208 12th SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.52 Acres
    Value Estimation
    $60,000
    208 12th SE St, Roanoke, VA 24013-1110
    View details
    941 Industry SE Ave

    941 Industry SE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 214,884 SF
    Value Estimation
    $9,335,000
    941 Industry SE Ave, Roanoke, VA 24013-2927
    View details
    3201 Williamson NW Rd

    3201 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,658 SF
    Value Estimation
    $445,000
    3201 Williamson NW Rd, Roanoke, VA 24012-4317
    View details
    302 Jefferson St

    302 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 28,626 SF
    Value Estimation by Request
    302 Jefferson St, Roanoke, VA 24011-1711
    View details
    2519 Johnson NW Ave

    2519 Johnson NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,540 SF
    Value Estimation
    $370,000
    2519 Johnson NW Ave, Roanoke, VA 24017
    View details
    3641 Blue Hls Vlg NE Dr

    3641 Blue Hls Vlg NE Dr

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.50 Acres
    Value Estimation
    $2,820,000
    3641 Blue Hls Vlg NE Dr, Roanoke, VA 24012-8615
    View details
    630 Bedford SW St

    630 Bedford SW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,000 SF
    Value Estimation
    $400,000
    630 Bedford SW St, Roanoke, VA 24015
    View details
    1003 Jefferson St

    1003 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,502 SF
    Value Estimation
    $290,000
    1003 Jefferson St, Roanoke, VA 24016-4405
    View details
    3 12th St SE St

    3 12th St SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,696 SF
    Value Estimation
    $220,000
    3 12th St SE St, Roanoke, VA 24013
    View details
    1122 Country Clb NW Dr

    1122 Country Clb NW Dr

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 24,145 SF
    Value Estimation by Request
    1122 Country Clb NW Dr, Roanoke, VA 24017
    View details
    1452 Towne Sq NW Blvd

    1452 Towne Sq NW Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 7,191 SF
    Value Estimation by Request
    1452 Towne Sq NW Blvd, Roanoke, VA 24012
    View details
    513 Salem SW Ave

    513 Salem SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 15,796 SF
    Value Estimation
    $890,000
    513 Salem SW Ave, Roanoke, VA 24016
    View details
    3215 Williamson NW Rd

    3215 Williamson NW Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 13,032 SF
    Value Estimation
    $880,000
    3215 Williamson NW Rd, Roanoke, VA 24012-4317
    View details
    2201 Railroad SW Ave

    2201 Railroad SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 22,960 SF
    Value Estimation
    $415,000
    2201 Railroad SW Ave, Roanoke, VA 24015-4803
    View details
    3 Riverside Cir

    3 Riverside Cir

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 186,725 SF
    Value Estimation by Request
    3 Riverside Cir, Roanoke, VA 24016-4955
    View details

    Roanoke, VA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2696 mixed-use properties for sale in Roanoke, VA on our real estate platform. These investment opportunities span a total of 77,161,841 square feet of properties for sale, with an estimated market value of $1,103,099,000.

    Prices for multi use buildings in Roanoke, VA start at $50,000, averaging $637,261, and reaching up to $12,815,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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    Most Searched ZIP Codes in Roanoke, VA

    • 24014
    • 24017
    • 24012
    • 24016
    • 24011
    • 24015
    • 24013
    • 24018
    • 24019

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