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    Roanoke, VA Mixed-use Properties for Sale

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    Downtown Roanoke Investment Opportunity
    $875,000
    0.05 Acres

    Downtown Roanoke Investment Opportunity

    22 Campbell Ave SE, Roanoke, VA 24011

    Two-unit building in vibrant downtown Roanoke with retail and residential.

    • Prime Downtown Roanoke location offering high visibility and accessibility.
    • Two‑unit building with commercial and residential income potential.
    • First floor retail space leased through March 31, 2030.
    • Modern, renovated 2bd/2bth residential unit on the second floor (available February 1, 2026).
    • High‑end finishes including recessed lighting, granite, and hardwoods.
    Updated: Nov 17, 2025
    View details
    Green Ridge Center: Roanoke, VA
    $1,649,000
    13,908 SF

    Green Ridge Center: Roanoke, VA

    2350 Peters Creek Rd, Roanoke, VA 24017

    Mixed-use center, high visibility, strong tenants.

    • Excellent visibility on Peters Creek Road, a major thoroughfare.
    • Median crossover provides convenient access.
    • New roof installed in 2018.
    • Multiple long‑term tenants.
    • 3,526 square feet of contiguous space available for owner‑occupant or new tenant.
    Updated: Dec 11, 2024
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    Prime Roanoke Commercial Land
    $980,000
    4.36 Acres

    Prime Roanoke Commercial Land

    4.36 acres, MX zoning, high traffic area

    4402 Old Rocky Mount Rd, Roanoke, VA 24014
    View details
    Based on your search, we've compiled 2702 Potential Opportunities for your consideration. Besides 3 Active listings in Roanoke, VA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 2695 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Lakefront Medical Office Opportunity
    $1,250,000
    3,200 SF

    Lakefront Medical Office Opportunity

    Smith Mountain Lake medical office building

    1027 Waterwheel Dr, Moneta, VA 24121
    View details
    Moneta Land with Mixed-Use Zoning
    $2,499,000
    60.60 Acres

    Moneta Land with Mixed-Use Zoning

    60.6 acres in Eastlake area with high visibility.

    15093 Moneta Rd, Moneta, VA 24121
    View details
    Mixed-Use Property with Owner Financing
    Contact for pricing

    Mixed-Use Property with Owner Financing

    High-visibility mixed-use property with owner financing potential.

    1173 Moneta Rd, Bedford, VA 24523
    View details
    Bedford Shopping Center Investment
    $799,500
    7,516 SF

    Bedford Shopping Center Investment

    7,516 SF, 8-unit shopping center, VA

    800 Blue Ridge Ave, Bedford, VA 24523
    View details

    Explore Off-Market Properties in Roanoke, VA

    Consider similar Off-Market properties in Roanoke, VA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    Shenandoah NW Ave

    Shenandoah NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.16 Acres
    Value Estimation by Request
    Shenandoah NW Ave, Roanoke, VA 24017
    View details
    206 Williamson SE Rd

    206 Williamson SE Rd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.77 Acres
    Value Estimation
    $645,000
    206 Williamson SE Rd, Roanoke, VA 24011-1806
    View details
    Roanoke SW Ave

    Roanoke SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2.77 Acres
    Value Estimation by Request
    Roanoke SW Ave, Roanoke, VA 24015
    View details
    5060 Rutgers NW St

    5060 Rutgers NW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.95 Acres
    Value Estimation by Request
    5060 Rutgers NW St, Roanoke, VA 24012
    View details
    15 Salem SW Ave

    15 Salem SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.75 Acres
    Value Estimation by Request
    15 Salem SW Ave, Roanoke, VA 24011
    View details
    2651 Brambleton SW Ave

    2651 Brambleton SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.42 Acres
    Value Estimation by Request
    2651 Brambleton SW Ave, Roanoke, VA 24015-4305
    View details
    24th NW St

    24th NW St

    MIXED USE (COMMERCIAL/INDUSTRIAL)
    Value Estimation by Request
    24th NW St, Roanoke, VA 24017
    View details
    Norfolk SW Ave

    Norfolk SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.05 Acres
    Value Estimation by Request
    Norfolk SW Ave, Roanoke, VA 24011
    View details
    Kirk SW Ave

    Kirk SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.03 Acres
    Value Estimation by Request
    Kirk SW Ave, Roanoke, VA 24011
    View details
    26 Luck SW Ave

    26 Luck SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.08 Acres
    Value Estimation by Request
    26 Luck SW Ave, Roanoke, VA 24011
    View details
    Orange NE Ave

    Orange NE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.11 Acres
    Value Estimation by Request
    Orange NE Ave, Roanoke, VA 24012
    View details
    Orange NW Ave

    Orange NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 0.14 Acres
    Value Estimation by Request
    Orange NW Ave, Roanoke, VA 24016
    View details
    2224 Jefferson SE St

    2224 Jefferson SE St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 14,119 SF
    Value Estimation
    $1,865,000
    2224 Jefferson SE St, Roanoke, VA 24014-2404
    View details
    505 Jefferson St

    505 Jefferson St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 8,000 SF
    Value Estimation
    $950,000
    505 Jefferson St, Roanoke, VA 24011-2405
    View details
    1718 Kenwood SE Blvd

    1718 Kenwood SE Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,300 SF
    Value Estimation by Request
    1718 Kenwood SE Blvd, Roanoke, VA 24013-2119
    View details
    615 Kimball NE Ave

    615 Kimball NE Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 5,000 SF
    Value Estimation by Request
    615 Kimball NE Ave, Roanoke, VA 24016
    View details
    1702 Loudon NW Ave

    1702 Loudon NW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 896 SF
    Value Estimation by Request
    1702 Loudon NW Ave, Roanoke, VA 24017-5542
    View details
    546 Luck SW Ave

    546 Luck SW Ave

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 4,825 SF
    Value Estimation by Request
    546 Luck SW Ave, Roanoke, VA 24016
    View details
    1906 Main SW St

    1906 Main SW St

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 2,006 SF
    Value Estimation by Request
    1906 Main SW St, Roanoke, VA 24015-3020
    View details
    4873 Vly Vw NW Blvd

    4873 Vly Vw NW Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 9,063 SF
    Value Estimation
    $1,700,000
    4873 Vly Vw NW Blvd, Roanoke, VA 24012-2086
    View details
    4822 Vly Vw NW Blvd

    4822 Vly Vw NW Blvd

    MIXED USE (COMMERCIAL/INDUSTRIAL) • 13,200 SF
    Value Estimation
    $2,480,000
    4822 Vly Vw NW Blvd, Roanoke, VA 24012-2025
    View details

    Roanoke, VA Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2698 mixed-use properties for sale in Roanoke, VA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 77,161,841 square feet of properties for sale, with an estimated market value of $1,103,099,000.

    Sale prices for multi use buildings in Roanoke, VA start at $50,000, averaging $637,261, and reaching up to $12,815,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    • 24011
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    • 24017
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