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    Florence, SC Mixed-use Properties for Sale

    6 results
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    Florence Commercial Lot For Sale
    $1,500,000
    4.02 Acres

    Florence Commercial Lot For Sale

    1714 2Nd Loop Rd, Florence, SC 29501

    4.02 acre mixed-use lot with high visibility in Florence, SC.

    • 260' of road frontage on 2nd Loop Road offers high visibility.
    • Zoned Mixed‑Use allows for a wide range of commercial and community‑oriented uses.
    • Permitted uses include schools, churches, retail, offices, restaurants, and hotels.
    • Conditional approval for multi‑family, live/work units, and other diverse uses.
    • Ideal location for businesses seeking high traffic and accessibility.
    Updated: Oct 24, 2025
    View details
    Florence Mixed-Use Investment Opportunity
    $500,000
    1.38 Acres

    Florence Mixed-Use Investment Opportunity

    0 Sc-327, Florence, SC 29506

    High-traffic SC-327 Retail & Restaurant Space

    • 1.38‑acre mixed‑use lot in Florence, SC, on US Hwy 327, priced at $500,000.
    • High‑visibility location adjacent to a RaceWay gas station.
    • Zoned for restaurant and pharmacy/drug store uses.
    • High traffic counts due to prime highway location.
    • Adjacent 1.38‑acre lots also available.
    Updated: Dec 11, 2024
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    Hwy 327 Mixed-Use Investment Opportunity
    $500,000
    1.38 Acres

    Hwy 327 Mixed-Use Investment Opportunity

    High-traffic Florence, SC retail center. Excellent visibility.

    0 Sc-327, Florence, SC 29506
    View details
    Florence, SC Hwy 76 Commercial Land
    $1,750,000
    10.55 Acres

    Florence, SC Hwy 76 Commercial Land

    10.55 Acres, Mixed-Use Development Potential

    0 Us-76, Florence, SC 29506
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    High-Traffic Florence Mixed-Use Property
    $975,000
    36.58 Acres

    High-Traffic Florence Mixed-Use Property

    Prime US-76 location, multi-use potential.

    0 Palmetto St, Florence, SC 29506
    View details
    High-Traffic Mixed-Use Florence SC
    $3,750,000
    105.44 Acres

    High-Traffic Mixed-Use Florence SC

    105 Acres, Multi-Use Investment Opportunity

    0 Williston Rd, Florence, SC 29506
    View details
    Based on your search, we've compiled 36 Potential Opportunities for your consideration. Besides 6 Active listings in Florence, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 26 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Sumter Car Wash & Land Investment
    $114,999
    1.48 Acres

    Sumter Car Wash & Land Investment

    High-yield car wash & income land.

    1694 Peach Orchard Rd, Sumter, SC 29154
    View details
    Corner Lot Near Downtown Sumter
    $150,000
    3 SF

    Corner Lot Near Downtown Sumter

    Corner lot with high visibility near downtown Sumter.

    420 S Lafayette Dr, Sumter, SC 29150
    View details
    Four Prime Laurinburg Outparcels
    $467,000
    7.35 Acres

    Four Prime Laurinburg Outparcels

    7.35 Acres, High-Traffic Retail Sites

    801 Westwood Way, Laurinburg, NC 28352
    View details
    Laurinburg Commercial Property with Warehouse
    $425,000
    5,706 SF

    Laurinburg Commercial Property with Warehouse

    Mixed-use property with office, storage, and development potential.

    204 E Railroad St, Laurinburg, NC 28352
    View details

    Explore Off-Market Properties in Florence, SC

    Consider similar Off-Market properties in Florence, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    208 Saunders St

    208 Saunders St

    OFFICE/RESIDENTIAL (MIXED USE) • 768 SF
    Value Estimation by Request
    208 Saunders St, Florence, SC 29501-2814
    View details
    130 Dargan St

    130 Dargan St

    Individual retail properties • 6,520 SF
    Value Estimation by Request
    130 Dargan St, Florence, SC 29506
    View details
    2702 Irby St

    2702 Irby St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,541 SF
    Value Estimation by Request
    2702 Irby St, Florence, SC 29505-3434
    View details
    1501 Palmetto St

    1501 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,912 SF
    Value Estimation by Request
    1501 Palmetto St, Florence, SC 29501-4131
    View details
    Palmetto St

    Palmetto St

    Multifamily properties • 36.58 Acres
    Value Estimation by Request
    0 Palmetto St, Florence, SC 29506
    View details
    1257 Sumter St, Unit 9

    1257 Sumter St, Unit 9

    OFFICE/RESIDENTIAL (MIXED USE) • 672 SF
    Value Estimation by Request
    1257 Sumter St, Florence, SC 29501-2209
    View details
    1459 Palmetto St

    1459 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,519 SF
    Value Estimation by Request
    1459 Palmetto St, Florence, SC 29501-4173
    View details
    1512 Palmetto St

    1512 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,780 SF
    Value Estimation by Request
    1512 Palmetto St, Florence, SC 29501-4132
    View details
    Us-76

    Us-76

    Lifestyle centers • 10.55 Acres
    Value Estimation by Request
    0 Us-76, Florence, SC 29506
    View details
    Sc-327

    Sc-327

    Lifestyle centers • 1.38 Acres
    Value Estimation by Request
    0 Sc-327, Florence, SC 29506
    View details
    554 Hickory Grv Cir

    554 Hickory Grv Cir

    OFFICE/RESIDENTIAL (MIXED USE)
    Value Estimation by Request
    554 Hickory Grv Cir, Florence, SC 29501-0810
    View details
    1368 Old Marion Hwy

    1368 Old Marion Hwy

    Mixed-use properties • 1,919 SF
    Value Estimation by Request
    1368 Old Marion Hwy, Florence, SC 29506
    View details
    1107 Evans St

    1107 Evans St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,216 SF
    Value Estimation by Request
    1107 Evans St, Florence, SC 29506-2739
    View details
    414 Irby St

    414 Irby St

    Retirement homes • 6,427 SF
    Value Estimation by Request
    414 Irby St, Florence, SC 29501
    View details
    1506 Palmetto St

    1506 Palmetto St

    OFFICE/RESIDENTIAL (MIXED USE) • 2,978 SF
    Value Estimation by Request
    1506 Palmetto St, Florence, SC 29501-4132
    View details
    Sc-327

    Sc-327

    Individual retail properties • 1.38 Acres
    Value Estimation by Request
    0 Sc-327, Florence, SC 29506
    View details
    100 Divine St

    100 Divine St

    OFFICE/RESIDENTIAL (MIXED USE) • 1,946 SF
    Value Estimation by Request
    100 Divine St, Florence, SC 29506-2732
    View details
    3218 Santee Riv Dr

    3218 Santee Riv Dr

    OFFICE/RESIDENTIAL (MIXED USE) • 2,816 SF
    Value Estimation by Request
    3218 Santee Riv Dr, Florence, SC 29501-9654
    View details

    Florence, SC Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 32 mixed-use properties for sale in Florence, SC, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 7,521,268 square feet of properties for sale, with an estimated market value of $10,945,000.

    Sale prices for multi use buildings in Florence, SC start at $115,000, averaging $781,785, and reaching up to $3,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Most Searched ZIP Codes in Florence, SC

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    • 29501
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