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    South Carolina Mixed-use Properties for Sale

    185 results
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    Hilton Head Commercial Townhome
    $579,000
    0.02 Acres

    Hilton Head Commercial Townhome

    17 Executive Park Rd, Hilton Head Island, SC 29928

    Two-story commercial building with income and value-add potential.

    • Immediate income from a fully renovated, leased upper level with a two‑year lease.
    • Vacant, freshly painted first floor offers flexible build‑out options for owner‑user or tenant.
    • Prime location on Hilton Head Island, close to major corridors, residential areas, and amenities.
    • Excellent investment opportunity with income stability and value‑add potential.
    • Townhome‑style commercial building provides a unique and appealing aesthetic.
    Updated: Feb 11
    View details
    New Ranch Home with CG Zoning
    $235,000
    0.16 Acres

    New Ranch Home with CG Zoning

    109 NW Haddock Rd, Orangeburg, SC 29115

    3-bedroom home with commercial zoning flexibility in Orangeburg, SC.

    • Commercial General (CG) zoning allows for residential or commercial use, providing exceptional flexibility.
    • Newly constructed 3‑bedroom, 2‑bath single‑story ranch home.
    • Adaptable floor plan suitable for residential living or conversion to professional/commercial space.
    • Ideal for owner‑occupants seeking residential living with future commercial flexibility or live/work potential.
    • Central heating and air conditioning.
    Updated: Feb 11
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    Historic Downtown Aiken Commercial Building
    $850,000
    3,049 SF

    Historic Downtown Aiken Commercial Building

    Two-story commercial building in downtown Aiken with mixed-use potential.

    344 Park Ave SE, Aiken, SC 29801
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    Versatile Ranch in Commercial Zone
    $239,000
    0.16 Acres

    Versatile Ranch in Commercial Zone

    New 3-bedroom ranch with commercial zoning flexibility.

    109 NW Haddock Rd, Orangeburg, SC 29115
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    Waterfront Mixed-Use Property in Beaufort
    $6,500,000
    5,000 SF

    Waterfront Mixed-Use Property in Beaufort

    Mixed-use property with panoramic waterfront views in downtown Beaufort, SC.

    916 Bay St, Beaufort, SC 29902
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    Historic Mixed-Use Building in Elloree
    $275,000
    5,928 SF

    Historic Mixed-Use Building in Elloree

    Prime investment opportunity in growing Elloree near Lake Marion.

    2720 W Cleveland St, Elloree, SC 29047
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    Cowpens Church/Multi-Use Building on Acreage
    $175,000
    2,991 SF

    Cowpens Church/Multi-Use Building on Acreage

    Charming church/multi-use building on 2.24 acres in central Cowpens.

    164 Washington Rd, Cowpens, SC 29330
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    King Street Mixed-Use Opportunity
    $1,195,000
    2,074 SF

    King Street Mixed-Use Opportunity

    Storefront business with upstairs living in a rapidly growing downtown location.

    680 King Street Ext, Charleston, SC 29403
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    Commercial Property on Highway 17
    $1,295,000
    1.44 Acres

    Commercial Property on Highway 17

    Over an acre commercial property with frontage on Highway 17.

    1479/1471 Highway 17, Little River, SC 29566
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    Seabrook Mixed-Use Commercial Building
    $299,000
    0.73 Acres

    Seabrook Mixed-Use Commercial Building

    Rare mixed-use property with high visibility and income potential.

    1887 Trask Pkwy, Seabrook, SC 29940
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    Versatile North Charleston Mixed-Use Property
    $399,999
    1,401 SF

    Versatile North Charleston Mixed-Use Property

    Unique property with main house, mobile home, and massive garage.

    8899 Salamander Rd, North Charleston, SC 29406
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    Historic Charleston Mixed-Use Income Property
    $4,399,000
    4,252 SF

    Historic Charleston Mixed-Use Income Property

    Renovated mixed-use property in downtown Charleston with commercial and residential income.

    21 Broad St, Charleston, SC 29401
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    Historic Charleston Mixed-Use Property
    $9,745,000
    13,334 SF

    Historic Charleston Mixed-Use Property

    Historic mixed-use property with residential and commercial units in Charleston.

    46-50 Queen St, Charleston, SC 29401
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    Versatile Commercial Building, Greenwood SC
    $159,000
    1,722 SF

    Versatile Commercial Building, Greenwood SC

    Adaptable commercial building with high visibility and flexible build-out options.

    1601 E Cambridge Ave, Greenwood, SC 29646
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    Mixed-Use Property in Spartanburg
    $200,000
    1,300 SF

    Mixed-Use Property in Spartanburg

    Investment opportunity with tenants in place near Spartanburg City Limits.

    170 S Blackstock Rd, Spartanburg, SC 29301
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    Versatile Commercial Property on Highway 28
    $1,200,000
    17,500 SF

    Versatile Commercial Property on Highway 28

    Two warehouse buildings totaling 17,500 SF on 1.67 acres.

    2810 Blue Ridge Blvd, West Union, SC 29696
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    Cowpens Mixed-Use Building For Sale
    $195,000
    1,700 SF

    Cowpens Mixed-Use Building For Sale

    Mixed-use building with recent upgrades in Cowpens, South Carolina.

    5286 S Main St, Cowpens, SC 29330
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    Historic Downtown Prosperity Commercial Space
    $275,000
    2,600 SF

    Historic Downtown Prosperity Commercial Space

    Flexible commercial space with historic charm in downtown Prosperity, SC.

    208 N Main St, Prosperity, SC 29127
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    Updated Ranch with Commercial Zoning
    $385,000
    0.50 Acres

    Updated Ranch with Commercial Zoning

    Updated brick ranch with commercial zoning and expansion potential.

    214 Lakeview Ter, Simpsonville, SC 29681
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    Historic Uptown Greenwood Commercial Property
    $749,000
    4,684 SF

    Historic Uptown Greenwood Commercial Property

    Versatile commercial space in a vibrant historic district with unique features.

    206 Main St, Greenwood, SC 29649
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    Waterfront Mixed-Use Landmark Property
    $6,500,000
    5,000 SF

    Waterfront Mixed-Use Landmark Property

    Unique mixed-use property with panoramic waterfront views in downtown Beaufort.

    916 Bay St, Beaufort, SC 29902
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    Beaufort Commercial Property with Waterfront
    $4,800,000
    1.48 Acres

    Beaufort Commercial Property with Waterfront

    Commercial property with apartments, retail spaces, deep water access.

    81 Sea Island Pkwy, Beaufort, SC 29907
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    Commercial Property Near Downtown Beaufort
    $3,000,000
    1.48 Acres

    Commercial Property Near Downtown Beaufort

    Income-generating commercial property with apartments and retail near downtown Beaufort.

    81 A Sea Is Pkwy, Beaufort, SC 29907
    View details
    Spartanburg Multi-Use Investment Opportunity
    $200,000
    0.71 Acres

    Spartanburg Multi-Use Investment Opportunity

    Investment property with tenants in place near Spartanburg city limits.

    170 S Blackstock Rd, Spartanburg, SC 29301
    View details

    South Carolina Mixed-Use Properties Investment Opportunities Market Analysis

    Explore 2173 mixed-use properties for sale in South Carolina, showcased through 185 active listings on our real estate platform. These investment opportunities span a total of 2,429,045,399 square feet of properties for sale, with an estimated market value of $590,263,707.

    Sale prices for multi use buildings in South Carolina start at $50,000, averaging $691,985, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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