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South Carolina Mixed-use Properties for Sale

200 results
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Lexington Commercial Property For Sale
$675,000
5,400 SF

Lexington Commercial Property For Sale

4350 Augusta Rd, Lexington, SC 29073

Mixed-use property with restaurant and office/warehouse space in Lexington.

  • Prime location on highly sought‑after Augusta Road.
  • Existing restaurant tenant provides $2,500/month income through November 2027.
  • Additional office/warehouse/event venue space offers potential rental income.
  • Tenant responsible for all utilities, services, and most maintenance including heating and air.
  • Two separate electrical meters (one for each building).
Updated: Mar 27
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Historic Edgefield Commercial Opportunity
$549,000
6,000 SF

Historic Edgefield Commercial Opportunity

303 Main St, Edgefield, SC 29824

Dual income property in historic downtown Edgefield.

  • Dual income potential: Main floor commercial space and six upper‑level rental units.
  • Fully renovated in 2022, including retail and rental spaces.
  • Prime location in historic downtown Edgefield.
  • Versatile space: Over 6,000 sq. ft. suitable for retail, restaurant, or other business ventures.
  • Six updated hotel‑style rooms, each with a kitchenette and full bathroom.
Updated: Mar 22
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Aiken Commercial Site For Sale
$495,000
7,824 SF

Aiken Commercial Site For Sale

Three buildings on 1.48 acres near downtown Aiken.

664 York St, Aiken, SC 29801
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Versatile Commercial Property on Highway
$350,000
2,590 SF

Versatile Commercial Property on Highway

Commercial property with office, shop, shed, and additional lot.

3477 Highway 102, Chesterfield, SC 29709
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Versatile Commercial Flex Property
$799,900
6,000 SF

Versatile Commercial Flex Property

6,000 sq ft commercial flex property in Greenwood, SC.

463 Calhoun Ave, Greenwood, SC 29646
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Versatile Commercial Property in Spartanburg
$799,000
2,900 SF

Versatile Commercial Property in Spartanburg

Functional space with expansion potential near Downtown Spartanburg.

449 W Centennial St, Spartanburg, SC 29303
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Greenville Redevelopment Opportunity
$449,609
0.50 Acres

Greenville Redevelopment Opportunity

0.5-acre property in Greenville's evolving corridor, ideal for redevelopment.

730 Wade Hampton Blvd, Greenville, SC 29609
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Historic Uptown Greenwood Commercial Property
$749,000
4,684 SF

Historic Uptown Greenwood Commercial Property

Versatile commercial space in a vibrant historic district with unique features.

206 Main St, Greenwood, SC 29649
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Improved Commercial Space in Union, SC
$197,000
4,300 SF

Improved Commercial Space in Union, SC

Unique commercial property with recent improvements and potential residential space.

226 E Main St, Union, SC 29379
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Prime Commercial Land in Beaufort
$525,000
0.39 Acres

Prime Commercial Land in Beaufort

Development opportunity in historic downtown Beaufort with high visibility.

1010 Boundary St, Beaufort, SC 29902
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Port Royal Mixed-Use Opportunity
$925,000
0.13 Acres

Port Royal Mixed-Use Opportunity

Mixed-use property in the heart of Port Royal, South Carolina.

1103 Paris Ave, Port Royal, SC 29935
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Historic Coca-Cola Plant Opportunity
$297,500
8,000 SF

Historic Coca-Cola Plant Opportunity

Historic building with modern potential, suitable for various uses.

100 Lightsey Street Ext, Hampton, SC 29924
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Columbia Mixed-Use Investment Opportunity
$2,999,000
1.74 Acres

Columbia Mixed-Use Investment Opportunity

Operating gas station, retail bays, home, and duplex on 1.74 acres.

1332 Broad River Rd, Columbia, SC 29210
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Versatile Mixed-Use Commercial Property
$750,000
0.48 Acres

Versatile Mixed-Use Commercial Property

Over 5,000 sq ft commercial property with residential area.

4327 Old Mill Rd, Anderson, SC 29623
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Versatile Commercial Building, Greenwood SC
$159,000
1,722 SF

Versatile Commercial Building, Greenwood SC

Adaptable commercial building with high visibility and flexible build-out options.

1601 E Cambridge Ave, Greenwood, SC 29646
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Commercial Property Near Interstate 26
$1,350,000
7,500 SF

Commercial Property Near Interstate 26

2.75 acre commercial property with 7,500 SF building.

1385 Meadow Farm Rd, Inman, SC 29349
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Hilton Head Development Opportunity
$875,000
2.00 Acres

Hilton Head Development Opportunity

2-acre multi-use land for commercial or residential development.

Farmers Club Rd, Hilton Head Island, SC 29926
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Iconic Mixed-Use Property, Greenwood SC
$479,000
4,753 SF

Iconic Mixed-Use Property, Greenwood SC

Mixed-use property in vibrant Uptown Greenwood, ideal for live/work.

204 Main St, Greenwood, SC 29649
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St. Helena Island Mixed-Use Land
$390,000
3.90 Acres

St. Helena Island Mixed-Use Land

3.9 acre mixed-use land with development potential.

785 Sea Island Pkwy, Saint Helena Island, SC 29920
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Historic Coca-Cola Plant for Sale
$297,000
8,000 SF

Historic Coca-Cola Plant for Sale

Historic building with modern potential, suitable for various commercial uses.

100 Lightsey Street Ext, Hampton, SC 29924
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Beaufort Commercial Land For Sale
$350,000

Beaufort Commercial Land For Sale

Commercial land in Shell Point area with high traffic count.

783 Parris Island Gtwy, Beaufort, SC 29906
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Versatile Commercial Property on Highway 28
$1,200,000
17,500 SF

Versatile Commercial Property on Highway 28

Two warehouse buildings totaling 17,500 SF on 1.67 acres.

2810 Blue Ridge Blvd, West Union, SC 29696
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Renovated Mixed-Use Property Near Downtown
$1,000,000
0.33 Acres

Renovated Mixed-Use Property Near Downtown

Charming, renovated property with development potential near downtown Greenville.

317 W Stone Ave, Greenville, SC 29609
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Bluffton Mixed-Use Condo For Sale
$1,200,000
3,000 SF

Bluffton Mixed-Use Condo For Sale

Class A condo in downtown Bluffton with flexible zoning.

1276 May River Rd, Bluffton, SC 29910
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South Carolina Mixed-Use Properties Investment Opportunities Market Analysis

Explore 2269 mixed-use properties for sale in South Carolina, showcased through 200 active listings on our real estate platform. These investment opportunities span a total of 2,430,716,879 square feet of properties for sale, with an estimated market value of $583,254,608.

Sale prices for multi use buildings in South Carolina start at $50,000, averaging $677,415, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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