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South Carolina Mixed-use Properties for Sale

184 results
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Versatile Ranch in Spartanburg, SC
$100,000
3,388 SF

Versatile Ranch in Spartanburg, SC

100 Clary Dr, Spartanburg, SC 29303

3388 SF mixed-use property with unlimited potential.

  • 3388 sq ft clear‑span, open interior offers unlimited potential for customization (single‑family, multi‑family, business).
  • Sturdy framing, level joists, and reinforced floors provide a solid foundation for various uses.
  • New roof installed last year.
  • Located in the back of a quiet, established neighborhood.
  • Approximately half‑acre lot.
Last Update: Dec 4
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New
Income-Generating Mixed-Use Property
$625,000
9,044 SF

Income-Generating Mixed-Use Property

2737 Cleveland St, Elloree, SC 29047

Nine income streams in revitalizing Elloree, South Carolina.

  • Nine income‑generating units provide diverse revenue streams.
  • Located in Elloree, SC, a rapidly growing small town.
  • Prime commercial spaces suitable for boutiques, offices, cafes, or studios.
  • Fully functioning short‑term rental unit ready to capitalize on Lake Marion visitor traffic.
  • Mix of unit types allows for flexibility in targeting short‑term and long‑term tenants.
Last Update: Dec 4
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Historic Chester Mixed-Use Investment Property
$284,900
0.08 Acres

Historic Chester Mixed-Use Investment Property

Mixed-use property with apartment and office space in historic district.
107 Gadsden St, Chester, SC 29706
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Historic Georgian Building in York
$1,125,000
0.39 Acres

Historic Georgian Building in York

Renovated mixed-use property with commercial spaces and residential condo.
8 Congress St, York, SC 29745
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New
Versatile Lexington Property with Updates
$400,000
1,808 SF

Versatile Lexington Property with Updates

Updated 1.13-acre property zoned for limited commercial use.
104 Round Knob Rd, Lexington, SC 29072
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Commercial Property on Highway 17
$1,199,500
Pending

Commercial Property on Highway 17

Over an acre with frontage and existing cash flow.
1479/1471 Highway 17, Little River, SC 29566
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Mixed-Use Property on Poinsett Highway
$699,000
1.07 Acres

Mixed-Use Property on Poinsett Highway

Mixed-use commercial property on 1.07 acres with highway frontage.
2821 Poinsett Hwy, Greenville, SC 29609
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King Street Mixed-Use Income Property
$1,150,000
2,040 SF

King Street Mixed-Use Income Property

Mixed-use property on King Street with commercial and residential potential.
680 King Street Ext, Charleston, SC 29403
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Mixed-Use Property in Downtown Charleston
$2,545,000
4,074 SF

Mixed-Use Property in Downtown Charleston

Flagship mixed-use property with commercial space and renovated residential units.
132 Spring St, Charleston, SC 29403
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Historic Mixed-Use Income Property
$4,399,000
4,278 SF

Historic Mixed-Use Income Property

Fully renovated, income-generating property in downtown Charleston.
21 Broad St, Charleston, SC 29401
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Versatile Property with Large Garage
$399,999
1,401 SF

Versatile Property with Large Garage

Unique mixed-use property with income potential in North Charleston.
8899 Salamander Rd, North Charleston, SC 29406
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Historic Uptown Greenwood Commercial Property
$749,000
4,684 SF

Historic Uptown Greenwood Commercial Property

Versatile commercial space in a vibrant historic district with unique features.
206 Main St, Greenwood, SC 29649
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12.7 Acres Mixed-Use Opportunity
$700,000
1 SF

12.7 Acres Mixed-Use Opportunity

Mixed-use property with cash flow, river access, and expansion potential.
1177 Richtex Rd, Winnsboro, SC 29180
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Versatile Commercial Property Near I-85
$430,000
Pending

Versatile Commercial Property Near I-85

Commercial building and move-in-ready home, ideal for business or investment.
1916 River Road Cir, Piedmont, SC 29673
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Renovated Live-Work Space on Acreage
$389,900
2,400 SF

Renovated Live-Work Space on Acreage

Remodeled live-work space on 1.5 acres, suitable for various uses.
1715 Cane Branch Rd, Loris, SC 29569
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Beaufort Commercial Compound on 7 Acres
$1,400,000
7.17 Acres

Beaufort Commercial Compound on 7 Acres

7-acre commercial compound with office, workshop, and storage.
25 Toppers Ln, Beaufort, SC 29906
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Paris Avenue Mixed-Use Property
$789,000
0.12 Acres

Paris Avenue Mixed-Use Property

Renovated mixed-use property in historic Port Royal, South Carolina.
1503 Paris Ave, Port Royal, SC 29935
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Beaufort Commercial/Residential Investment Opportunity
$899,000
0.11 Acres

Beaufort Commercial/Residential Investment Opportunity

Income-generating property in historic Beaufort's sought-after neighborhood.
409 Carteret St, Beaufort, SC 29902
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Commercial Property Near Downtown Beaufort
$3,000,000
1.48 Acres

Commercial Property Near Downtown Beaufort

Mixed-use property with apartments and commercial spaces near downtown Beaufort.
81 A Sea Is Pkwy, Beaufort, SC 29907
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Turnkey Restaurant Investment Opportunity
$1,499,000
0.30 Acres

Turnkey Restaurant Investment Opportunity

Prime Lowcountry real estate, updated restaurant with upstairs living unit.
925 10Th St, Port Royal, SC 29935
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Beaufort Land for Sale
$525,000
0.35 Acres

Beaufort Land for Sale

Two lots zoned for residential/commercial use in Beaufort, SC.
1207 Rodgers St, Beaufort, SC 29902
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Port Royal Commercial Opportunity
$925,000
0.13 Acres

Port Royal Commercial Opportunity

Commercial property in the heart of Port Royal, South Carolina.
1103 Paris Ave, Port Royal, SC 29935
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Graniteville Mixed-Use Repair Facility
$450,000
3,172 SF

Graniteville Mixed-Use Repair Facility

Turnkey auto repair facility with residential component on 1.81 acres.
32 Oakwood Dr, Graniteville, SC 29829
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Highway 21 Mixed-Use Opportunity
$650,000
0.47 Acres

Highway 21 Mixed-Use Opportunity

Versatile property on Harbor Island with Highway 21 frontage.
2123 Sea Island Pkwy, Saint Helena Island, SC 29920
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South Carolina Mixed-Use Properties Investment Opportunities Market Analysis

Explore 2170 mixed-use properties for sale in South Carolina, showcased through 184 active listings on our real estate platform. These investment opportunities span a total of 2,453,951,265 square feet of properties for sale, with an estimated market value of $579,220,098.

Prices for multi use buildings in South Carolina start at $50,000, averaging $678,243, and reaching up to $25,000,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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